Immune checkpoint inhibitor–associated nephritis—treatment standard ABSTRACT. Over the last 13 years, the use of immune checkpoint inhibitor (ICI) therapy has grown remarkably, owing to their unprecedented anti-tumor effica

Immune checkpoint inhibitor–associated nephritis—treatment standard
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Treatment strategies of the thromboembolic risk in kidney failure patients with atrial fibrillation ABSTRACT. The incidence and prevalence of atrial fibrillation (AF) in patients affected by kidney failure, i.e. glomerular filtration rate <15 ml/min/1.

Treatment strategies of the thromboembolic risk in kidney failure patients with atrial fibrillation
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Hyperkalemia treatment standard ABSTRACT. Hyperkalemia is a common electrolyte disturbance in both inpatient and outpatient clinical practice. The severity and associated risk depends on

Hyperkalemia treatment standard
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Anaemia in CKD—treatment standard ABSTRACT. Anaemia is one of the most common complications of chronic kidney disease (CKD), having a significant impact on quality of life, and is also asso

Anaemia in CKD—treatment standard
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ANCA-associated vasculitis—treatment standard ABSTRACT. Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are characterized by small-vessel necrotizing inflammation, and prior t

ANCA-associated vasculitis—treatment standard
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C3G and Ig-MPGN—treatment standard ABSTRACT. Among the broad spectrum of membranoproliferative glomerulonephritis (MPGN), immunofluorescence distinguishes C3 glomerulopathy (C3G), with predo

C3G and Ig-MPGN—treatment standard
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IgA nephropathy in adults—treatment standard ABSTRACT. Immunoglobulin A nephropathy (IgAN) is the most common primary form of glomerular disease worldwide and carries a high lifetime risk of kidney fa

IgA nephropathy in adults—treatment standard
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Sepsis-associated acute kidney injury—treatment standard ABSTRACT. Sepsis is a host's deleterious response to infection, which could lead to life-threatening organ dysfunction. Sepsis-associated acute kidney inju

Sepsis-associated acute kidney injury—treatment standard
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Hypertension in chronic kidney disease—treatment standard 2023 ABSTRACT. Hypertension is very common and remains often poorly controlled in patients with chronic kidney disease (CKD). Accurate blood pressure (BP) measu

Hypertension in chronic kidney disease—treatment standard 2023
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Metabolic alkalosis treatment standard ABSTRACT. The kidney is poised to defend against development of metabolic alkalosis through non-adaptive mechanisms in the proximal nephron and adaptive pr

Metabolic alkalosis treatment standard
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Light-chain (AL) amyloidosis for nephrologists—treatment standard ABSTRACT. Amyloidosis is a group of complex diseases caused by the misfolding and aggregation of proteins into amyloid fibrils. Light-chain (AL) amyloidosi

Light-chain (AL) amyloidosis for nephrologists—treatment standard
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BK Polyomavirus-associated nephropathy – diagnostic and treatment standard ABSTRACT. BK polyomavirus (BKPyV) is recognized as a significant viral complication of kidney transplantation. Prompt immunosuppression reduction reduces e

BK Polyomavirus-associated nephropathy – diagnostic and treatment standard
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Antibody-mediated rejection—treatment standard ABSTRACT. Antibody-mediated rejection (AMR) remains a major cause of graft failure, with significant health and economic burden. Despite being recognized &

Antibody-mediated rejection—treatment standard
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Treatment standard: CKD in the geriatric patient ABSTRACT. The number of older people with chronic kidney disease (CKD) is increasing globally. The vast majority of these patients will die before they eve

Treatment standard: CKD in the geriatric patient
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Acute post-streptococcal glomerulonephritis in children—treatment standard ABSTRACT. Acute post-streptococcal glomerulonephritis (APSGN) is the leading cause of acute glomerulonephritis in children worldwide, owing to the high inc

Acute post-streptococcal glomerulonephritis in children—treatment standard
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Life support in hemodialysis emergencies—treatment standard ABSTRACT. Hemodialysis removes uremic toxins and excess water and sodium from the blood of patients with kidney failure. For the last 60 years, this techni

Life support in hemodialysis emergencies—treatment standard
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Kidney disease after hematopoietic stem cell transplant—treatment standard ABSTRACT. Hematopoietic stem cell transplant (HSCT) is a well-established procedure for malignant and nonmalignant conditions. Despite its therapeutic bene

Kidney disease after hematopoietic stem cell transplant—treatment standard
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Anti-glomerular basement membrane disease—treatment standard ABSTRACT. We review the current standards of treatment and discuss novel developments in the pathophysiology, diagnosis, outcome prediction and management

Anti-glomerular basement membrane disease—treatment standard
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Management of monoclonal gammopathy of renal significance: treatment standard ABSTRACT. Monoclonal gammopathy of renal significance (MGRS) is a heterogeneous group of clonal B cell or plasma cell proliferative disorders that cause ki

Management of monoclonal gammopathy of renal significance: treatment standard
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IDF Diabetes Atlas 11th edition 2025: global prevalence and projections for 2050 The prevalence and the burden of chronic kidney disease (CKD) are both rising steadily around the world [1]. Much of this rise can be attributed to a major

IDF Diabetes Atlas 11th edition 2025: global prevalence and projections for 2050
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The multiple autoantibodies in anti-GBM disease Anti-glomerular basement membrane (GBM) disease has long been viewed as a prototypic, organ-specific autoimmune disease defined by autoreactivity to a sing

The multiple autoantibodies in anti-GBM disease
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Genome-wide donor–recipient non-HLA mismatch and graft loss ABSTRACT. HLA-matching between donor (D) and recipient (R) is routinely performed in kidney allocation to optimize allograft survival but explains only a m

Genome-wide donor–recipient non-HLA mismatch and graft loss
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Chronic lung diseases and kidney disease: pathophysiology and management ABSTRACT. Acute kidney injury (AKI) is a critical complication in patients with chronic lung diseases (CLD), particularly during acute exacerbations. This

Chronic lung diseases and kidney disease: pathophysiology and management
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Treatment of diabetes in patients with advanced chronic kidney disease or kidney failure ABSTRACT. Chronic kidney disease (CKD) is common in both type 1 and type 2 diabetes and complicated glycemic control due to fluctuating insulin resistance

Treatment of diabetes in patients with advanced chronic kidney disease or kidney failure
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Anti-glomerular basement membrane disease—treatment standard ABSTRACT. We review the current standards of treatment and discuss novel developments in the pathophysiology, diagnosis, outcome prediction and management

Anti-glomerular basement membrane disease—treatment standard
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Perlecan is a novel target of autoantibodies in anti-glomerular basement membrane disease ABSTRACTBackground. Anti-glomerular basement membrane (anti-GBM) disease is an autoimmune kidney disease in which autoantibodies are directed against GBM c

Perlecan is a novel target of autoantibodies in anti-glomerular basement membrane disease
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Cardioprotection from intradialytic exercise: a randomized trial ABSTRACTBackground and hypothesis. Left ventricular (LV) regional wall motion abnormalities (RWMAs) related to transient ischemic events are well documente

Cardioprotection from intradialytic exercise: a randomized trial
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Genotype–phenotype correlations and clinical outcomes of genetic TRPC6 podocytopathies ABSTRACTBackground and hypothesis. Podocytopathy associated with likely pathogenic/pathogenic variants of Transient receptor potential cation channel subfa

Genotype–phenotype correlations and clinical outcomes of genetic TRPC6 podocytopathies
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Urinary rituximab loss and rate of treatment failure in membranous nephropathy ABSTRACTBackground. Rituximab is a first-line treatment for primary membranous nephropathy, but approximately one-third of patients fail to respond. Among

Urinary rituximab loss and rate of treatment failure in membranous nephropathy
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Association between exposure to air pollution and kidney function decline ABSTRACTBackground and hypothesis. Chronic kidney disease is a major global health concern, with air pollution increasingly recognized as a key contributor

Association between exposure to air pollution and kidney function decline
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