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Posts by Penny Lewthwaite

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UK guidelines for the investigation and management of eosinophilia in returning travellers and migrants Eosinophilia is a common finding in returning travellers, migrants and other travelling groups. In this setting it often indicates an underlying helminth infection. Infections associated with eosinoph...

First paper to share here

Delightful to have been part of the all new UK guidelines on the diagnosis of and management of eosinophilia!

www.journalofinfection.com/article/S016...

1 year ago 100 28 9 9
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Mpox outbreak—tecovirimat resistance, management approaches, and challenges in HIV-endemic regions Mpox is a viral infection that causes acute disease in humans and can be fatal. On Aug 14, 2024, the WHO declared the ongoing mpox outbreak to be a global public health emergency. Shifting transmissio...

www.thelancet.com/journals/lan...

@thelancetinfdis full of interesting emerging virus information this month.

Interesting article on PLWH, mpox and tecivorimat resistance

1 year ago 8 1 1 0
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Diagnostic accuracy of three mpox lateral flow assays for antigen detection in the Democratic Republic of Congo and the United Kingdom https://www.medrxiv.org/content/10.1101/2024.11.07.24316894v1 Background: The ongoing outbreaks of mpox, the disease caused by monkeypox virus (MPXV) highlight th

Diagnostic accuracy of three mpox lateral flow assays for antigen detection in the Democratic Republic of Congo and the United Kingdom www.medrxiv.org/content/10.1101/2024.11....

1 year ago 1 1 0 0
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When it rains it pours: Rwanda reports finding an unspecified number of #Marburg cases in "health facilities" — note that's plural — in the country.
Do not like the look of this.

1 year ago 42 20 2 1
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Rwanda reports first-ever Marburg virus disease outbreak, with 26 cases confirmed Brazzaville/Kigali – Rwandan health authorities are intensifying outbreak control efforts following the detection of Marburg virus disease, with 26 cases confirmed and six deaths reported currently.

1. Rwanda's first detected #Marburg outbreak is already the 4th (maybe really the 5th) largest Marburg outbreak ever. Stunning to see 26 cases & 6 deaths already; those numbers reflect spread in healthcare settings. Hopefully they get a handle on this quickly. www.afro.who.int/countries/rw...

1 year ago 66 43 1 5
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The worsening mpox outbreak in Africa: a call to action The escalating incidence of mpox in Africa has led the Africa Centres for Disease Control and Prevention to declare its first-ever Public Health Emergency of Continental Security and prompted WHO to i...

🆕 Our commentary in Lancet ID: “The worsening mpox outbreak in Africa: a call to action.”

Urgent action is needed to:
1. Scale up testing/surveillance
2. Study research gaps
3. Invest in vaccines/therapeutics
4. Boost care quality
5. Tailor community outreach

www.thelancet.com/journals/lan...

1 year ago 34 24 0 1
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First-ever delivery of mpox vaccines in Africa outside of clinical trials arrives in Nigeria Nigeria today received 10 000 doses of mpox vaccines, becoming the first country in the African region to receive doses to respond to the outbreak of the viral disease that has affected several…

“Nigeria today received 10,000 doses of mpox vaccines, becoming the first country in the African region to receive doses to respond to the outbreak of the viral disease that has affected several countries.”

www.afro.who.int/countries/nigeria/news/f...

1 year ago 17 5 0 0
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Pathoplexus| Home Pathoplexus is a new, open-source database dedicated to the efficient sharing of human viral pathogen genomic data, fostering global collaboration and public health response.

One of the reasons I've been quiet on Bluesky for a few months is because I've been working on something big - something I'm really happy to share now! Pathoplexus.org
A new, open-source database for pathogen sequence sharing. 👐🧬🌎

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1 year ago 381 148 8 7
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Modelling the effectiveness of an isolation strategy for managing mpox outbreaks with variable infectiousness profiles - Nature Communications Current guidelines recommend that individuals exposed to mpox should isolate for three weeks, based on the average estimated incubation period. Here, the authors use a quantitative model to characteri...

Modelling the effectiveness of an isolation strategy for managing mpox outbreaks with variable infectiousness profiles

www.nature.com/articles/s41...

1 year ago 3 3 2 0
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Happy to be added.😊

1 year ago 1 0 0 0

Thankyou for the list!

1 year ago 1 0 2 0
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Making pandemic planning part of the everyday Health in all policies is also emergency preparedness in all policies, writes Christina Pagel The UK Covid-19 inquiry’s module 1 report on the resilience and preparedness of the UK had “no hesitation...

A new short piece by me in the BMJ reflecting on the Covid-19 Inquiry Module 1 report and how "emergency planning" needs to be incorporated into "everyday planning"

www.bmj.com/content/386/...

1 year ago 153 52 7 1

jackpot

#mpox

1 year ago 12 4 1 0

New WHO position paper on smallpox and mpox vaccines.

Via Rosamund Lewis from X.

iris.who.int/bitstream/ha...

1 year ago 37 13 0 0
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Mpox: Thailand confirms Clade 1b strain for first time in Asia The European man flew into Thailand from an unnamed African country last week, officials say.

Hot off the press. Thailands case of mpox is in fact the new viriulent strain of Clade 1b. They're now tracking down his contacts and those sitting close to him on the plane. Fingers crossed this has been contained. (71) www.bbc.co.uk/news/article...

1 year ago 12 8 2 0