PolyGenie: a reproducible Nextflow pipeline for phenome-wide association studies using polygenic risk scores www.biorxiv.org/content/10.1... 🧬💻🧪 github.com/gcatbiobank/...
Posts by Pablo Marin-Garcia
“Iran is held hostage by its own regime—
but haunted by the fate of countries the West tried to ‘save.’
"We live between two truths:
The regime is deeply dysfunctional—decades of repression and mismanagement.
Foreign ‘solutions’ mean collapse—we’ve watched Iraq, Libya, Syria, Afghanistan. 1/2
Brown recluse envenomation should be considered in children presenting with cellulitis & sepsis who subsequently develop #warmAIHA, as #HemolyticLoxoscelism can manifest with direct antiglobulin test positivity & mimic drug-induced pathology.
Learn more: https://bit.ly/4qVSZ2E
#RareDisease #MedSky
Comic. [2x2 chart. Top left quadrant: seem like dinosaurs x are dinosaurs. Silhouettes of dinosaurs stegosaurus, triceratops, tyrannosaurus, velociraptor, and long-neck dinosaur. Top right quadrant: seem like dinosaurs x are not dinosaurs. Silhouettes of mosasaur, quetzalcoatlus, dimetrodon, plesiosaur, and pteranodon. Bottom left quadrant: don’t seem like dinosaurs x are dinosaurs. Silhouettes of penguin, egret, ostrich, pigeon, falcon. Bottom right: don’t seem like dinosaurs x are not dinosaurs. Silhouettes of squirrel, stapler, plant, person, and bicycle.]
Dinosaurs And Non-Dinosaurs
xkcd.com/3204/
Democracy is when voters choose their leaders. Autocracy is when leaders choose their voters.
@biorxivpreprint.bsky.social Modeling mitochondrial inheritance enables high-precision single-cell lineage tracing in humans
www.biorxiv.org/content/10.6... @bloodgenes.bsky.social @jswlab.bsky.social @bostonchildrens.bsky.social @hhmi-science.bsky.social @broadinstitute.org
Facebook plans to put facial recognition in its glasses and they think we’re too stupid to fight back.
Their internal memo: “We will launch during a dynamic political environment where many civil society groups that we would expect to attack us would have their resources focused on other concerns.”
Delighted to see the TrumpActionTracker feature in this @timeshighered.bsky.social profile by @patrickjack.bsky.social today :-)
was great to chat to him about it!
www.timeshighereducation.com/news/mathema...
Tracker here
www.trumpactiontracker.info
One Boston Children’s Hospital researcher said, “This is like asking, how do you think dropping an atomic bomb on New York City will affect the future of Broadway musicals? This is a generational loss of innovation, technology, and economic power.” www.bostonglobe.com/2026/02/09/m...
Today is the #InternationalDayofWomenandGirlsinScience - celebrating women across our @helloeacr.bsky.social community 🙌
From Board members across Europe to the #EACR HQ team and the scientists we serve worldwide, women play a central role in advancing cancer research every day
#WomeninScience 👩🏻🔬🧪
In case you missed it yesterday...
I usually repost #dataViz and #dataJournalism I love. This by @jburnmurdoch.ft.com is excellent —but I don't like what it means...
I will never not love this video of bats filmed upside down to make it look like they're at a goth nightclub
This is freaking fantastic
BREAKING: Bernie Sanders is introducing an amendment to cut ICE’s $75 billion funding increase, and to use those funds to restore the federal cuts to health care.
I think that the current situation is "I no longer *Type* code" but I still Create/design/rewrite.
Probably is time just to make UML diagrams and good arquitectura designs. (I remember the claims of "Rational Rose back in a early 2000)
Probably we should came back to the model of "apprentice" for software engineers, where the new "extreme-programming" model could be work in pairs senior-junior, no writing code but reviewing it, to see good and bad practices copy-pasted by IA.
Actions speak louder than words.
Tom Homan says he wants to do things differently, but we have yet to see meaningful change.
The only way to ensure the safety of the people of Minnesota is for the federal government to draw down their forces and end this campaign of brutality.
Top engineers at Anthropic, OpenAI say AI now writes 100% of their code | Fortune share.google/wumkP5BbywN8...
Very interesting point, but misleading. This is a view from a senior software engineer.
He no longer *write* code, probably he only direct what the code should do, and he review the code.
Last year, we made the decision to step away from X.
The Royal Irish Academy is committed to creating, convening, and sharing knowledge for the public good and as an organisation we value Independence; Integrity; Curiosity; Openness and Rigour.
In our view, X no longer aligns with these values
@hcrichardson.bsky.social wrote about a 1945 US leaflet on how to spot fascism in America.
I thought it might be worth screenshotting the relevant bit.
ALL of the these warnings have come to pass in the past year. 1/2
Weekly Recap: The science of responsible innovation, rv (uv for R), just quit, #Rstats updates (R Data Scientist, R Works), 5 things in #biosecurity, why benchmarking is hard, open science (?), papers & preprints doi.org/10.59350/jae...
We saw Jan 6, 2021 and Jan 7, 2026 with our own eyes.
This is not Orwell's 1984.
Should be a straightforward murder conviction.
Warning: gift link goes to NY Times video showing video of the murder.
Vaccines, the most impressive public health intervention in medical history, and where we could be headed if there was not efforts to negate truth, facts, and evidence
A great, open-access, review and perspective by @scientificdiscovery.dev
One really understands the dangers of a mad dictator drunk on power when it’s family movie night and the 8yo gets a veto-free choice of movies.
Cool new paper from @bloodgenes.bsky.social in @science.org. A common non-coding germline variant protects against clonal haem (CHIP) by modifying RNA regulatory networks. Wonder if CHIP protection is a tradeoff though - presumably some impact on immunity...? www.science.org/doi/10.1126/...
579 high-quality human genomes from @humanpangenome.bsky.social, Arab Pangenome and individual papers (CHM13, CN1, KSA001, I002C, YAO and KOREF1). Sequences available in the AGC format (3.7GB) and FM-index in the ropebwt3 format (20.3GB). For details, see github.com/lh3/human-asm