here is the correct link: www.researchgate.net/publication/...

We have been playing with different methods. These days SHAP. for more details: www.biorxiv.org/content/10.6...

-Transdisciplinary teams are a necessity, not a nicety, for equitable pain care
-AI can help us move toward personalized, scalable pain care, but needs to be built with human oversight to be most effective

Key takeaways:
-Chronic pain lacks objective biomarkers, making AI predictions especially vulnerable to misinterpretation
-Expert-driven feature selection improves both model performance AND fairness
-Explainable AI is essential; black-box systems undermine clinical trust and patient autonomy

(PDF) Chronic pain and the limits of artificial intelligence: why expert knowledge matters PDF | AI is transforming chronic pain research, but without the right human input, it risks compounding the very problems it aims to solve. In our... | Find, read and cite all the research you need on...

New article: AI can transform chronic pain care, but without the right human input, it risks compounding the very problems it aims to solve. We suggest to build it in a way so that we can understand pain.

Hashmi MA & Hashmi JA, PAIN (2026)

doi.org/10.1097/j.pa...

l1nq.com/lg9vhcq

got it. thanks for sharing.

why so? I was thinking of reading it

Email from "Brain" subject "Need your response"

How it's going.

Neuroanatomy reflects individual variability in impulsivity in youth - Molecular Psychiatry Molecular Psychiatry - Neuroanatomy reflects individual variability in impulsivity in youth

Our latest work looking at the neuroanatomical basis of impulsivity in youth is out now in Molecular Psychiatry!

Graphical abstract showing four panels. Panel 1: a person in an MRI scanner with blue cognitive thought bubbles drifting from their head and pink body thought bubbles from their torso, with organs glowing inside. Panel 2: blue bubbles for cognitive items (Self, Words, Focus, Images, Future, Past) are larger than pink bubbles for body items (Breathing, Movement, Stomach, Heart, Skin, Bladder), with arrows showing body thoughts link to more negative and less positive emotion. Panel 3: physiological traces (EGG, ECG, respiratory) show higher arousal with body-wandering; a bar chart shows cognitive items (Past, Future, Repetitive, Vivid) correlate with more ADHD and depression symptoms while body items (Breath, Stomach, Skin, Heart) correlate with fewer. Panel 4: medial brain with thalamus, somatomotor cortex, and interoceptive regions highlighted, plus a chord diagram showing connectivity between these three regions.

New paper in PNAS! When the mind wanders, it often drifts to the body. We call this "body-wandering". These thoughts are often negative, but are associated with reduced ADHD & depression symptoms, driven by a distinct interoceptive-allostatic brain signature. pnas.org/doi/10.1073/pnas.2520822123

More evidence that the homeostatic pathway lamina 1 theory has no feet.

Graphical abstract showing three panels. Left panel, "Multiorgan Interoception Measures," depicts a translucent human body silhouette with anatomically rendered heart (red) and lungs (blue), accompanied by schematic icons for three psychophysical tasks: the Respiratory Resistance Sensitivity Task (RRST), Heart Rate Discrimination Task (HRDT), and an auditory control condition. N = 241 participants. Center panel, "Psychophysical Modelling and Individual Differences," shows a fan of overlapping sigmoid psychometric curves in blue-to-red gradient representing individual variation in perceptual threshold (α) and precision (β), a hierarchical Bayesian model diagram, and icons for metacognitive bias and M-Ratio efficiency. Right panel, "Key Finding: No Cross-Modal Relationship," displays a scatterplot of cardiac versus respiratory sensitivity with a flat regression line (r ≈ 0, BF₀₁ > 6), a compact Bayes Factor heatmap with mostly blue null-supporting cells and one orange cell indicating that subjective confidence is shared across modalities (r = 0.51***). Takeaway: interoceptive ability is modality-specific.

Is there a single "interoceptive sense"? Our new study in
@commspsychol.nature.com says: probably not. In 241 participants, cardiac and respiratory interoception were completely uncorrelated — only subjective confidence was shared across domains. www.nature.com/articles/s44... #psychscisky 🧪

Another day, another stupid Excel chart.

🔥My first paper is out in Synthese — open access:

“From simulating to duplicating the brain”🔥

link.springer.com/article/10.1...

Abstract below.

Would love to hear what you think (and especially any objections / counterexamples).

@springernature.com

New paper in Imaging Neuroscience by Maëlig Chauvel, Cyril Poupon, et al:

Evolutionary signatures in deep white matter architecture: A comparative study of humans and chimpanzees

doi.org/10.1162/IMAG...

preprint🥳

Connectome-wide mega-analysis identifies a reproducible functional network signature of temporal lobe epilepsy

-hypo+hyper connectivity
-patient/site consistent
-constrained by 🧠 wiring
-tracks clinical status and info for outcome

by @kexie.bsky.social et al

doi.org/10.64898/202...

Check out our new paper, and join this webinar where @drjkhokhar.bsky.social and I will discuss the science and more!

www.eneuro.org/content/13/2...

I love the internet

Don't be so careful in time of death ✊😔

An Open-Source Restraint System for Magnetic Resonance Imaging in Awake Rats Magnetic resonance imaging (MRI) is a critical tool for translational neuroscience, but preclinical studies frequently rely on anesthesia, which alters neural activity and limits comparison with human...

Excited to share this in final form @sfnjournals.bsky.social: An Open-Source Restraint System for Magnetic Resonance Imaging in Awake Rats www.eneuro.org/content/13/2... if anyone wants to try doing it, give us a call! Happy to help you get going!

The strongest version of this illusion I’ve seen! Absolute head-wrecker!

Something big is happening in AI — and most people will be blindsided | Fortune It’s not like a light switch... more like the moment you realize the water has been rising around you and is now at your chest.

This piece really nails how I have been feeling in the last couple of weeks. fortune.com/2026/02/11/s...

"..hippocampal-prefrontal systems represent emotion concepts in a map-like way at multiple levels of abstraction.."

Map-like representations of emotion knowledge in hippocampal-prefrontal systems
by
@yumengma.bsky.social and @pkragel.bsky.social

www.nature.com/articles/s41...

Forward vs Inverse problems: why high performance machine learning usually means little about how the world works Understanding causality from machine learning is unfortunately usually impossible; life sciences take note

Well-predicting machine learning in no way means that you can understand how the world works.
open.substack.com/pub/kording/...

As Joe says! Hear, hear.

www.thetransmitter.org/the-big-pict...

Sir Ian McKellen performing a monologue from Shakespeare’s Sir Thomas More on the Stephen Colbert show. Never have I heard this monologue performed with such a keen sense of prescience. Nor have I ever been in this exact historical moment.TY Sir Ian, for reaching us once again.
#Pinks #ProudBlue

The cortex layer 6b theory of attention www.cell.com/neuron/fullt...

or

this thorn in my side
is from the seeds I've planted
(Bleeding ol' me)

being super kind to yourself and others either through a sense of humour or honesty is wisdom enough. rest, relax, rejuvenate!

may the healing process bring you even more wisdom