🎄 Day 14 of the 24 Days of Development ✨🧬
Interested in the history of cellular dedifferentiation🧫? Explore Betty Hay’s pioneering contributions and how her work continues to shape regeneration biology🦎 doi.org/10.1016/j.yd...

Just updated, our work on a regeneration-specific factor that regulates WNT ligand availability to control regeneration.

Congratulations to our very own Si Cave and Weston John Quinn on graduating and earning their doctoral titles! Best of luck for the future! #graduation #asu

(D-D′) The peripheral DRWNT activity (yellow arrowhead) is lost upon Stat92E knockdown, while JNK activity is unaffected. (E) Posterior-specific Stat92E knockdown (hh-GAL4) shows reduced DRWNT in posterior wound periphery (yellow arrowheads) compared to wild-type anterior; anterior/posterior boundary indicated by dashed line. (F) DRWNTΔSTAT-GFP (lacking Stat92E sites) shows loss of peripheral activity at 18 h AHS (yellow arrowhead)

A threshold level of JNK activates damage-responsive enhancers via JAK/STAT to promote tissue regeneration

Read this #LifelongDevSI #OA Research Article by John W. Quinn, Robin E. Harris and colleagues in our Stem Cells and Regeneration section doi.org/10.1242/dev....

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