Article titled, "Impact of the Diabetes Endothelial Keratoplasty Study" by Kathryn A. Colby, MD, PhD, and Andrea L. Blitzer, MD. Article discusses a study on corneal transplants and diabetes.

💬 Invited Commentary: The DEKS trial showed that donor diabetes did not compromise 1-year DMEK graft success or endothelial cell loss, supporting broader use of diabetic donor tissue to help address corneal tissue shortages.

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JAMA Ophthalmology. RCT: Donor Diabetes and 1-Year Descemet Membrane Endothelial Keratoplasty Success Rate. Population: 466 Men, 631 Women. Intervention: 1421 Eyes, 1097 participants. Findings: Graft success rate. Donor without diabetes 96.3%, Donor with diabetes 97.1%.

RCT: The 1-year success rate of Descemet membrane endothelial keratoplasty was similarly high for corneas from donors with or without diabetes, supporting unrestricted use of diabetic donor tissue.

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Figure showing endothelial cell density over one year. A) Stratified by donor diabetes status, B) Stratified by donor diabetes severity group, C) Stratified by donor diabetes severity score.

RCT: The diabetes status of cornea donors did not affect endothelial cell loss or morphometric parameters one year after Descemet membrane endothelial keratoplasty, supporting the use of donor corneas from people with diabetes.

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Futuristic eye and brain graphic courtesy of ARPA-H with the caption “what if we could cure blindness?”

#NEWS | Eversight is part of a major undertaking that will bring together more than 40 scientists, doctors and industry experts hand-picked from around the country to make vision-restoring whole eye transplants a reality: eversight.ws/4gyhL4n.

#ophthalmology #medsky #cornea #ophthosky #neurosky

ARPA-H announces pioneering investments to restore vision to people who are blind The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs ranging from molecular to societal to provide transformative hea...

What if we could cure blindness?

Announcing the teams on our THEA program working to enable whole functional eye transplantation to restore vision for the blind and visually impaired. arpa-h.gov/news-and-eve...