If you're interested in hearing about lymph node metastasis, tumor evolution, T cells, and immunotherapy, check out this @theNCI forum tomorrow, featuring Mary Jo Turk, @naxerova, and Alexander Huang. events.cancer.gov/dcb/tdln #TDLNForums

Congrats Mario on an amazing story and a herculean effort!

Lymph node metastasis is almost always synonymous with cancer progression, but in this fantastic study from @ubellackerlab.bsky.social, they reveal that it also imparts a key metabolic vulnerability: FSP1 dependency. Congrats Jess and @mariopalma.bsky.social!

Evolution Under Therapy: Resistance Mechanisms—
Andrew J. Aguirre, Nathan Reticker-Flynn, Susan M. Rosenberg, and Kathleen Burkhardt will address this topic in a plenary at the AACR Special Conference on Cancer Evolution (Dec 4-6; Albuquerque).
buff.ly/4ecfgxE
#AACRevol25 @retickerflynn.bsky.social

Hot off the presses! Was an honor to team up with Scott Dixon @stanforduniversity.bsky.social on this Nature Cancer review. We reflect on hurdles that have slowed translation of ferroptosis-directed therapies and share ideas on what it will take to bring these therapies to the clinic. rdcu.be/eBbqV

Lymphatic collection and cell isolation from mouse models for multiomic profiling Nature Protocols - An approach to collect lymph drained from the primary tumor in mice enables the downstream characterization of the samples using metabolomics, lipidomics and flow cytometry.

And if you're interested in investigating what is happening in the lymph fluid itself, check out this great protocol by the
@ubellackerlab.bsky.social‬
www.nature.com/articles/s4...

NBF0LN6-987AL Cell Line Sixth generation cell line derived from an ipsilateral axillary lymph node metastasis of a fifth-generation line

If you're interested in trying out these protocols in your own lab, we are making the cell lines available through @CancerToolsOrg
cancertools.org/cell-lines/...

And the commentary by the great von Andrian lab
bsky.app/profile/nat...

Interested in studying lymph node metastasis? Check out our protocol by Cort Breuer out today in @natprot.nature.com
bsky.app/profile/nat...

Really cool! Congrats Julia.

Great study Michelle. Congrats!

Life Science Research Professional 1 in School of Medicine, Stanford, California, United States Stanford University is seeking a Life Science Research Professional 1 to perform basic functions and activities involved in defined research projects....

Our lab has an opening for a new Research Assistant (LSRP) starting this Summer/Fall. If you're interested in joining a vibrant community working at the interfaces of cancer metastasis and adaptive immunity, apply here:
careersearch.stanford.edu/jobs/life-sc...

Congrats Leeat!

Redirecting immune signaling with cytokine adaptors Nature Communications - Cytokines are immune signaling molecules that are frequently dysregulated in disease. Here, the authors create engineered cytokine ‘adaptors,’ molecular switches...

Excited to share this work from the Garcia Lab out today in @naturecomms.bsky.social! We engineer "cytokine adaptors", molecular immune switches that simultaneously block a target cytokine while inducing local activation of alternative cytokine receptors. rdcu.be/ec7GS

Thanks Klaus!

First Bluesky post! If you're interested in hearing about our work, check out this seminar in a couple weeks.