stay tuned for upcoming/related quantitative genetics manuscript...
Posts by Andrew Whitehead
very fun and integrative study, collab. w Nann Fangue, led by Joanna Griffiths
@jogriffiths61.bsky.social, who persevered despite 1st year experiments disrupted by pandemic, record heat wave (while trying to control rearing temperatures), and a direct lightning strike to our experimental facility!
thermal tolerance acclimation with rearing temperature, and divergence between lowly-domesticated and highly-domesticated fish
Are you interested in domestication selection and conservation physiology?
Newest paper @evolappjournal.bsky.social: Highly and Lowly Domesticated Endangered Fish From a Conservation Hatchery Diverge in Their Thermal Physiology, Transcriptome, and Methylome
onlinelibrary.wiley.com/doi/10.1111/...
Confused writing is usually a symptom of confused thinking. As we struggle to clarify writing, we clarify our thoughts. AI writing aids rob us of that struggle, leaving clean-looking text and thoughts still confused for lack of inspection. Writing is not just a product; it is a diagnostic tool.
Research on the tenacious little killifish sheds light on how exposure to crude oil and flame retardants impacts later generations. From @andrewwhitehead.bsky.social @ucdavis.bsky.social
Flame-retardant paper #2: shows that exposure in one generation has neurobehavioral impacts on offspring. Even brief exposure during embryo development - their offspring years later inherited altered behavior.
pubs.acs.org/doi/10.1021/...
Flame-retardant paper #1: we show that brief exposures during early life to PBDE flame retardants have neurobehavioral effects that can last a lifetime, but whether exposure is maternal or directly from the environment modulates toxic outcomes
pubs.acs.org/doi/10.1021/...
2 new papers now out in #ES&T on the persistent and multi-generational impacts of flame retardants on behavior and brain biology
Press release from @ucdavis.bsky.social @ucdaviscaes.bsky.social that ties this with our work on multi-gen impacts of oil spills www.ucdavis.edu/climate/news...
🚨Research alert 🚨
A tiny fish with transparent embryos is helping #UCDavis researchers shed new light on how maternal exposure to crude oil and flame retardants can affect later generations. #DeepwaterHorizon #PBTE
caes.ucdavis.edu/news/materna...
My system is very sophisticated. A running list on my Notes app.😬
Our collaborative study shows that hatchery domestication in Delta smelt elevates thermal tolerance but reduces plasticity, with transcriptome and methylome shifts influencing adaptation. Read the preprint here: www.biorxiv.org/content/10.1...
stay tuned for two more papers coming out in the next few weeks on persistent and multi-generational impacts of exposures to ubiquitous flame retardant pollutants...
New paper out in #ES&T where we show that killifish exposure to crude oil has impacts (on embryo/larval development and transcriptome) that propagate to their offspring and to their grand-offspring. pubs.acs.org/doi/full/10....
@acs.org
I am thrilled to announce that in January 2026 I will be starting my own lab at NYU Biology! Soon enough I will be recruiting postdocs and students! Please reach out if you are interested with a CV and description of your research interests, or if you know of people who could be interested! 🧬🗽 🦊
Drosophila picticornis, a Hawaiian fly with patterned wings
Wish I could be at #Evol2025 this year! I’ll be starting a new lab at NYU this fall, and will be recruiting at all levels. Please spread the word if you know anyone who wants to work on evo. genomics, phylogenies, and comparative development of inverts (like Hawaiian Drosophila!) shchurch.github.io
The aim of this proposal is to place population genomic insights into a comparative framework to gain fundamental insights into the determinants of evolutionary outcomes. The project will work within LepEU, the European Lepidopteran Population Genomics Consortium (https://lepeu.github.io/). LepEU provides access to field samples from European populations of diverse species. Chromosome-scale reference genomes are provided by Project Psyche (https://www.projectpsyche.org/). Networking during the postdoc will be facilitated by participation in the 10kLepGenomes COST Action (https://10klepgenomes.eu/). Existing datasets await analysis, while additional samples need DNA extraction and submission for sequencing. Functional validation capability (CRISPR/Cas9 gene manipulations) is also available to test emergent hypotheses of allele-to-phenotype impacts. Personal research interests of the postdoc will be important to determine the exact project, as the project has a generous sequencing budget.
The successful applicant should have a PhD (obtained within 6 years of the application deadline) in a suitable subject area, such as evolutionary biology or population genomics. A strong interest in population genomics, local adaptation, comparative analyses, and experience working with genomic-scale data is essential. The candidate must have a documented publication record demonstrating relevant skills. Experience working with bioinformatic pipelines (e.g., Snakemake), or working with butterflies is welcome but not essential. The net salary is 28,000 SEK/month (~2,430 Euro, not subject to Swedish income tax) and comes directly from the Carl-Trygger Foundation stipend, which is paid out directly to the postdoc. Only PhD candidates acquired outside of the host department can apply. Currently, the lab of Prof. Wheat consists of 3 postdoctoral researchers, while the Dept. of Zoology provides a vibrant and excellent research environment of active, dynamic researchers. Applications should include: i) a succinct description of research interests and experience, detailing your contribution to any relevant publications (max 1 page), ii) why you are the ideal candidate for this position in the lab (max 1 page); iii) a CV including a list of publications, and iv) the name and contact information of two personal references. Applications will be reviewed on a rolling basis with a deadline of 23 August 2025. The project is planned to start on 1 October, but flexibility in the starting date can be provided for a suitable candidate. Please contact Prof. Wheat for additional information.
🚨Postdoc opportunity🚨: LepEU postdoc: comparative population genomics of European scale adaptation in butterflies
2 year, full-time PD in my group, Stockholm Univ.
Applications assed on rolling basis, deadline: 23 August 2025. Planned start 1 Oct.
Details:
christopherwheatlab.wordpress.com
Anya Brown - @dranyabrown.bsky.social, marine scientist at @ucdavis.bsky.social & Nat Geo Explorer, studies how coral microbes shape reef resilience. “It’s the kind of thing that unites so much of life on Earth,” she says. 🌊🪸🐠
Read more in Nat Geo: www.nationalgeographic.com/impact/artic...
This is a great thread, with some really nice talking points for your letters to your reps, your protest signs, your zines and flyers, and your conversations with neighbors.
"Our calculations suggest that the proposed budgetary cuts to the NIH will create a social cost that is 16 times greater than the savings that the administration is attempting to achieve."
jamanetwork.com/journals/jam...
Super excited to release a huge evolution project on the works for many years:
Evolution experiments synchronized across climates to understand rapid adaptation
Preprint: doi.org/10.1101/2025...
All data available: www.grene-net.org/data
#MOILAB
@ucberkeleyofficial.bsky.social
@hhmi.org
🧵👇
Wow. This looks awesome. Lab group will be reading this!
🚨 A new rule would let career scientists like NSF/NIH program officers be replaced by political appointees
Already 14,000+ public comments, deadline is Friday
📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful
Speak up! shorturl.at/WKuBj
Interested in evolution in the Anthropocene?
In a paper out today we use a mechanism-guided approach to predict & show that evolved resistance to urban pollutants offers cross-resistance to oil in killifish, via adaptive change in AHR signaling
doi.org/10.1111/eva....
@evolappjournal.bsky.social
What are your favorites?
New @science.org
Exposomics. We're not doing nearly enough to understand and mitigate our toxic environmental exposures. A very insightful perspective
www.science.org/doi/10.1126/...
🙏 We need your help 🙏
The government continues to cancel grants at both NIH and NSF to censor science it doesn't like.
We're tracking terminations to organize and advocate. Please report your terminated grants:
NIH:
forms.gle/J2znQ7y7YpeP...
NSF: airtable.com/appGKlSVeXni...
w/ @noamross.net
Students seemed relieved to hear that faculty recognize the challenges, are concerned for them, invested in their future, & are listening. Though institutes seem afraid to message support for students these days, perhaps support is best communicated in small groups with folks whose faces we know
Main message from faculty: Work hard on the things within your control...
- take advantage of out-of-classroom opportunities to build breadth/depth of experience, including work in lab, internships, etc
- get to know your professors
- engage with professional organizations
- build pro network
Hosted listening sessions with undergrad students in our program over the past 2 days. Their main concerns (perhaps unsurprisingly):
- students from non-traditional identities worried if institute has their backs
- worry about grad school prospects, job prospects, loss of educational opportunities
Those pants look pretty corny