Our new preprint reveals that 🪰's Cnn and 🪱's SPD-5 both form condensates in vitro, but assemble via divergent mechanisms in vivo. We show how phosphorylation unlocks Cnn’s autoinhibited scaffold and identify conserved features in 🚶♂️'s CDK5RAP2.
Today we welcomed MP Adam Thompson(@adamthompsonmp.bsky.social) to the Dunn School, part of the @royalsociety.org Pairing Scheme.
Adam got to see our science in action and share his reflections on a career in science and politics with our students and postdocs. Thanks for your visit Adam!
The Company of Biologists 100 logo to the left and QR code to the right. Portrait of Jordan Raff to the left, text to the right 100 extraordinary biologists Jordan Raff Former Company Director and Founding Editor-in-Chief of Biology Open, Jordan Raff is based at the University of Oxford. His lab works to understand the basic molecular mechanisms that regulate the assembly and function of centrioles and centrosomes. #100biologists #biologists100
We are featuring Jordan Raff as our next extraordinary biologist. He is a former Company Director and Founding Editor-in-Chief of Biology Open. #100biologists
@jordanraff.bsky.social
Many congratulations to all our postdocs recently awarded postdoctoral fellowships! 🥳
A special mention to @carokobras.bsky.social for a BBSRC Fellowship, and Emma and Laura for @wellcometrust.bsky.social early career awards!
Check the full list here: www.path.ox.ac.uk/news-article...
🔬 Exciting findings from our collaborative study with Lea, Raff, van Breugel&Feng Lab! We've uncovered how Spd-2/CEP192 proteins with an SP2D structure are crucial for centrosome assembly. Crystal structures&mutations reveal new insights into PCM scaffold formation.
www.science.org/doi/10.1126/...
#biologists100
Please come to my poster on Wed at the Liverpool conference and see how the @jrafflab.bsky.social with @dunngogreen.bsky.social @dunnschool.bsky.social is conducting our world class science in an environment friendly way at @ox.ac.uk ! Saving money & planet! There is no planet B!
🔬 Excited to share our latest paper! We’ve found how Spd-2 coordinates with Polo and Aurora A to build critical scaffolds in centrosome assembly in Drosophila. 🧬 www.science.org/doi/10.1126/...
Happy to be here. Hopefully this will be fun and useful. Like Twitter used to be.