Cambodian MOH Announces 4th Human #H5N1 Case of 2026, according to my sources.

Krammer, et al: Population immunity to clade 2.3.4.4b H5N1 is dominated by anti-neuraminidase antibodies

journals.asm.org/doi/epdf/10....

#H5N1

Incredible work by Jonathan Pekar et al.: The emergence and molecular evolution of H5N1 influenza viruses in United States dairy cattle

www.biorxiv.org/content/10.6...

Science: Two years after it emerged, ‘cow flu’ is still circulating—and baffling scientists

by Jon Cohen @science.org @cohenjon.bsky.social

bit.ly/3O7uDpg

h5n1

First imported human case of influenza A(H9N2) infection in the EU A human case of avian influenza A(H9N2) infection in a returning traveller from a non-European country where the virus has previously been identified in birds, has been reported in the Lombardy region...

First imported human case of influenza A(H9N2) infection in the EU.

A human case of avian influenza A(H9N2) infection in a returning traveller from a non-European country where the virus has previously been identified in birds, has been reported in Lombardy, Italy.

bit.ly/3O1bVj6

#AvianFlu

On the brink of emergence: an evolutionary approach to #Influenza A virus #H5N1 isolated from #humans

On the brink of emergence: an evolutionary approach to #Influenza A virus #H5N1 isolated from #humans, etidiohnew.blogspot.com/2026/03/on-b...

Serological surveillance of avian influenza virus H9N2 subtype in occupational populations exposed to poultry environment in China during 2018–2023

«The highest seroprevalence was observed in individuals exposed to live poultry market (1.51%).

doi.org/10.1093/ofid...

#H5N1 adjacent #h9n2

Eid Mubarak, New York.

California’s Avian Flu Safety Rules Are Strong — Their Enforcement Isn’t As H5N1 infects over 70% of the state’s dairy herds, exposed farmworkers are left without PPE or mitigation training in their native language. And some aren’t informed of an outbreak at all.

As H5N1 infects over 70% of the state’s dairy herds, exposed farmworkers are left without PPE or mitigation training in their native language. And some aren’t informed of an outbreak at all.

Tomorrow @agri.europarl.europa.eu will hold its structured dialogue with Commissioner Varhelyi.

I damn well hope that MEPs publicly challenge him on this reported decision to propose bogus welfare standards, rather than ban the cruel practice of fur farming as citizens demanded.

Polymerase trapping as the mechanism of H5 highly pathogenic avian influenza virus genesis Highly pathogenic avian influenza viruses (HPAIVs) derive from H5 and H7 low pathogenic avian influenza viruses (LPAIVs). Although insertion of a furin-cleavable multibasic cleavage site (MBCS) in the...

Polymerase trapping as the mechanism of H5 highly pathogenic avian influenza virus genesis

«Our results show that MBCS acquisition is the result of the combination of insertion-prone RNA sequences and the formation of transient RNA structures.»

www.science.org/doi/10.1126/...

#H5N1

Distribution of the total number of HPAI virus detections reported in Europe by week of suspicion (dates indicate the first day of the week) and affected wild bird categories, from 1 October 2020 to 27 February 2026.

Just published: Avian influenza overview
December 2025–February 2026. Recommended, even just for this figure showing virus detections in wild birds found dead in Europe between 2020 and 2026. Note the high level of detections in waterfowl during the past winter. www.efsa.europa.eu/en/efsajourn...

H5N1 bird flu spreads to sea otters and sea lions along San Mateo coast, wildlife experts say After H5N1 bird flu was detected in elephant seals gathered at Ano Nuevo State Park, other marine mammals have also succumbed, including a sea otter and sea lion. So far, only animals in San Mateo County have been affected.

H5N1 bird flu spreads to sea otters and sea lions along San Mateo coast, wildlife experts say

«In summary, our findings support the emergence of a new clade 2.3.4.4b reassortant virus provisionally classified as genotype B3.14 and the first ever global human case of an HPAI A(H5N2) virus infection»

www.nature.com/articles/s41...

#H5N1 adjacent #h5n2

Sci Reports: Emergence of a novel reassorted high pathogenicity avian influenza A(H5N2) virus associated with severe pneumonia in a young adult

Joel Armando Vázquez-Pérez et al

go.nature.com/40TyusQ

We vaccinated cows twice with 500ug of our H5 mRNA-LNP vaccine and observed very high levels of H5-reactive antibodies in serum and milk following vaccination. 2/

Holy cow! Our new study showing that H5 mRNA-LNP vaccines are safe and effective in lactating dairy cows is now posted on @biorxivpreprint.bsky.social!

We found that our vaccine elicits protective responses in 2,000 pound dairy cows! 1/

www.biorxiv.org/content/10.6...

Dynamics of natural selection preceding human viral epidemics and pandemics Using a phylogenetic framework to characterize natural selection, we investigate the hypothesis that zoonotic viruses require adaptation prior to zoon…

There's a common misconception that zoonotic viruses require significant adaptation to jump from animals to cause human epidemics.

Not so 👇.

Further, we see clear signs of 1977 flu experiencing cell passage, prior to epidemic.

SARS-CoV-2? Business as usual.

www.sciencedirect.com/science/arti...

⚠️ H5N1 avian influenza has been confirmed in northern elephant seals at Año Nuevo. The first cases in CA marine mammals. UCSC researchers are conducting urgent monitoring & testing 🦭Your gift keeps researchers in the field when it matters most: https://bit.ly/4sjJj3j

bioRxiv: Surveillance on California dairy farms reveals multiple possible sources of H5N1 transmission

A.J. Campbell et al

bit.ly/4l4ghSA

Does seasonal influenza vaccine against H5N1. Bioinfo analysis + serology. pre-existing immunity from vaccination or prior exposures may influence responses to this zoonotic threat
👉 journals.sagepub.com/doi/full/10....

Wild birds drive the introduction, maintenance, and spread of H5N1 clade 2.3.4.4b high pathogenicity avian influenza viruses in Spain, 2021-2022 https://pubmed.ncbi.nlm.nih.gov/41743171/

This is very concerning in view of the massive H5N1 flu-related mortality observed in southern elephant seals. A small pilot study suggests that an H5N1 flu vaccine is safe and immunogenic in elephant seals. Logistics of vaccine administration look complicated, though.

First Cases of Highly Pathogenic Avian Influenza in Northern Elephant Seals Confirmed in California Seven weaned elephant seal pups in California’s Año Nuevo State Park tested positive for highly pathogenic avian influenza (HPAI) H5N1, the U.S. Department of Agriculture’s National Veterinary Service...

UC Davis: First Cases of Highly Pathogenic Avian Influenza in Northern Elephant Seals Confirmed in California

h5n1 @ucdavis.bsky.social
bit.ly/4r2FrCH

Bay Area seals come down with bird flu, alarming California researchers Seven elephant seal pups at a state park in the Bay Area have tested positive for highly pathogenic H5N1 bird flu, marking the first confirmed cases in marine mammals in California.

Seven elephant seal pups at a state park in the Bay Area have tested positive for highly pathogenic H5N1 bird flu, marking the first confirmed cases in marine mammals in California.

#3 – Avian Influenza: From Wild Birds to Humans

Sharing for Dr. Florian Krammer: This week's episode of viroLOGICAL focuses on avian influenza, specifically H5N1 and the current issues we have with it.
Spotify: open.spotify.com/show/2LxUpju...
Apple: podcasts.apple.com/at/podcast/v...
Podigee: virological.podigee.io

Deadly bird flu found in California elephant seals for the first time Researchers at UC Davis say news they've dreaded since 2023 has come to pass: California's elephant seals have been infected with H5N1 bird flu.

#H5N1 #BirdFlu detected in northern elephant seals on CA coast. Virus annihilated the funny-looking seals in South America between 2022 and 2024. From UC Davis and UC Santa Cruz research. www.latimes.com/science/stor...

CEIRR's Nextstrain interactive dashboard showing phylogenetic tree and global transmission map of h5nx virus samples.

The CEIRR Website now features a Nextstrain page! This page hosts an H5N1 build that has been enriched with phenotypic characterization data provided by the CEIRR RAP group. Check it out today: https://ow.ly/6EIF50YljGR

Highly Pathogenic Avian Influenza A (H5N1) Caused Mass Death Among Black-Legged Kittiwakes (Rissa tridactyla) in Norway, 2023

«…HPAI is likely to have caused a colony population reduction of at least 50%.»

onlinelibrary.wiley.com/doi/10.1155/...

#H5N1

«…newly circulating bovine B3.13 genotype H5N1 virus demonstrates increased fitness compared to the avian B1.1 genotype H5N1 virus from prior to the bovine H5N1 outbreak, and that cattle have potential capacity to operate as mixing vessels….»

journals.asm.org/doi/10.1128/...

#H5N1