Can we all agree that “interested should be the first reply to a post from Will?

I wasn’t either but we ran a few a while back and WOW they lit up

Terminal alkynes are much higher energy (via DSC) than internal
Even just capping with TMS makes a big difference

Yeah that’ll do it

Sorry Matt, I hijacked your “compound goes boom” without knowing/before I saw your post

Balancing Energy and Stability: A Tetracyclic Bis(trinitromethyl)-Functionalized Triazole-Oxadiazole with High Density Bis(trinitromethyl)oxadiazole compounds exhibit excellent detonation properties, but their thermal stability is poor, with a thermal decomposition temperature typically below 120 °C. To address this c...

Hope they didn’t look like this:
#ChemSky go boom

Landman. Watch it.

Soon as I saw it … no way it’s clean

1000% excited for the patients that it might work but it’s def not selective

The last time the Bruins played only 40 min was last week

(Dateline) Maranello Italy:
In other news, Ferrari has developed an automobile that can complete a marathon at least twice as fast as a human

Let us know when it’s “clean out the liquor cabinet” time at The Chemist house

Scientists From Every Field Agree That AI Will Make Every Other Field Obsolete SAN FRANCISCO, CA—In a rare moment of interdisciplinary consensus, scientists from every major field of biomedical research confirmed Tuesday that artificial intelligence has rendered every other fiel...

Scientists From Every Field Agree That AI Will Make Every Other Field Obsolete

(Follow @inprep.bsky.social !!!)

a sign with four red circles with a line through them, signifying "do not" use these things when you are doing your "discovery route" because it's doesn't necessarily translate to a useful process and your process team will have to redo everything anyway. in the four circles: 1. a flash column - meaning avoid column chromatography. 2. -78 degrees C, 400 degrees C in a sealed tube - meaning don't use silly reaction conditions. 3. hexane, dichloromethane and dimethylformamide - meaning don't use these solevnts. 4. sodium hydride, HF, TBDMSCl, CH2N2, OsO4 - meaning these are not great reagents for scale. avoid protection/deprotection and hazardous reagents.

And while we are at it...let's not forget about the poor old process chemists.....

#chemsky #chemchat #Chemistry

We’re doing what?

AI: for (A)ll the (I)mportant things

That could be a quote for a lot of different situations

“enough redeeming features” is definitely going in my end-of-year performance management review

I see now why you’ve never invited a Bruins Fan to talk

“As this article isn’t that serious either” is quite an awesome statement

Booo

Professor in Synthetic Organic Chemistry University of California, Irvine is hiring. Apply now!

Please RT!

The Dept of Chemistry at UC Irvine invites applications for a tenured faculty position in Synthetic Organic Chemistry. Deadline: July 1, 2026.

More information about the position can be found here: recruit.ap.uci.edu/JPF10109

@uciphyssci.bsky.social

5 Surprising Facts About Rush's '2112' - That Eric Alper Here’s something worth sitting with for a moment. It’s 1976. Three guys from Toronto — a bassist who sounds like he’s singing from another planet, a guitarist who grew up on Cream and Led Zeppelin, and a drummer who reads Ayn Rand on tour buses — are about to get dropped by their record label. […]

Did you know the closing words of Rush's "2112" accidentally encode the album title numerically — and Alex Lifeson says it was completely unintentional? Five surprising facts about one of rock's greatest records. zurl.co/SSKkA

The Stars and Sabres lined up after the game to congratulate linesman Steve Barton for working his final NHL game

Reason # 348 the NHL is best

Stars and Sabres lining up after the game to shake hands with one of the refs who is retiring after the game

Russell’s is still there? I went so many times with my parents growing up

Trump is not capable of making sound decisions on behalf of the United States. The media should cover his unfitness for office nonstop, while Congress must move swiftly to relieve him of his responsibilities.

Anything less demonstrates a fundamental unserious attitude toward governing a superpower.

The TungStans

On this day in 1971, Stevie Wonder delivered one of Sesame Street’s most unforgettable moments with a funky, seven minute version of "Superstition." zurl.co/Ls46L

Furiously Googling “has a Master’s champion ever played the wrong fairway on the last hole?”

Signs that I’m old…
Justin Rose is 45

45…I’ll always see him as that teenager who almost won the Open (T-4 1998 British Open as a 17yo)