You are an annoying undeclared bot

Claude Code became very reluctant to do anything remotely connected to viral sequence data some time in the last few weeks. (I'm quite sympathetic, but also I will now have to use Codex)

Action Cam Footage From October 2017 Spacewalk YouTube video by NASA

and the youtube algorithm just served me up this video from 2017 www.youtube.com/watch?v=Wfoy...

(Yeah my terminology is made up and confusing!)

(I do agree with everyone that a separate detailed methods section/appendix with full reproducible methods is also important!)

Identification and genomic characterization of BA.3.2: a highly divergent BA.3-related SARS-CoV-2 lineage from southern Africa Abstract. In November 2024, a highly divergent BA.3-related severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineage, designated BA.3.2, was de

An example of Intro, Methods, Results: academic.oup.com/ve/article/1...
An example of what I'm calling Intro,Methods-And-Interleaved-Results: www.cell.com/cell/fulltex...

The section is typically actually just titled Results, but it actually includes the basic methods by necessity.

indeed - but the brand of master mix can IMO be kept for the supplemental. IME Intro, Methods, Results papers force you to read a whole section incl. the brand of master mix before you can get to any data (and if you read it out of sequence you don't have enought context to understand the results)

Huh, my intuition would be that as a non-expert the interleaved would actually be especially useful for ease-of-understanding: a popular science book would tell a narrative "they did X and found that.."

But agree that extra methods sections with a lot of precision (often as supplemental) is useful

Most research is some combination of the two. Agree the separate version reflects the process in the case of work that could be published as a registered report. Nature/Cell/Science style is essentially a succession of methods and results sections (+ extra sec at the end for methods in more detail)

and the latter is much closer to the reality of most processes, where initial results inform subsequent methods

Introduction, Methods, Results papers are much less readable than Introduction, Methods-And-Interleaved-Results papers

Artemis II crew calls International Space Station in historic first YouTube video by VideoFromSpace

they should get the chinese on a conference call

yes this is on the basis that they are linked both by the uterus and separately by peritoneal cavity

Does seem to me like the fallopian tubes should add at least one to the genus which is fun for increasing the population variation

I had a long conversation with a confused claude

More than I thought
howmanypeopleareinspacerightnow.com

there is a very excellent exhibit at the san francisco Exploratorium museum that illustrates this. there is a black background, and you push a button, and a swatch of white paint flips up in front of it.

Graph of receptor binding curves showing an ancestral and recent H5N1. The ancestral virus does not bind NeuGc receptor well, whereas the recent virus birds NeuGc and NeuAc containing receptors equally.

Really excited to be able to share our latest preprint, describing how during its evolution in cattle, H5N1 has got better at using a type of alternative receptor that's abundant in cows, but not found in humans and birds.

www.biorxiv.org/content/10.6...

Screenshot of a browser window with an interactive graphic. At the center is the Earth. The Moon is in the upper right, with the line of its orbit drawn across the screen from right to left. A loopy blue line leads from the Earth to a point further along the Moon’s orbit in the upper left, and back to Earth. A circle on the blue path is labeled “Orion”, which is the name of the spacecraft for the Artemis II mission. At the bottom of the screen, four dials show the mission elapsed time, Orion’s velocity, its distance from Earth, and its distance to the Moon.

Artemis Real-time Orbit Website: www.nasa.gov/missions/art...

artemis toilet drama rabbit hole ttu-ir.tdl.org/server/api/c...

quite right!

You are *not* going to guess the explanation for this one.

Invasive Meningococcal Disease outbreak 2026: technical briefing 1

Further details on the meningococcal genome and genomic epidemiology including data release info from the recent explosive Kent outbreak: www.gov.uk/government/p...

Statistical Rethinking 2026 is done: 20 new lectures emphasizing logical and critical statistical workflow, from basics of probability theory to causal inference to reliable computation to sensitivity. It's all free, made just for you. Lecture list and links: github.com/rmcelreath/s...

It's just limited to the handles at the time I imported the data

Some provisional analysis on one of the genomes from the menB outbreak detailed below:
johnlees.me/posts/menb-o...

I did my PhD on bacterial meningitis, finding whether there are genetic factors which make meningitis more likely.

Wrote down some initial thoughts on the current outbreak in Kent: johnlees.me/posts/menb-o...

I tried to think of factors and their likelihood to explain why this is happening now

You can now view a tree of 2,399,238 bacterial genomes we made from AllTheBacteria (on the great Taxonium):
taxonium.org/atb
That's a big tree!

(unless you're used to SC2 trees)

as someone who invariably gets a shaving cut before crucial events, which I'd learnt of styptic pencils sooner - en.wikipedia.org/wiki/Antihem...

is anyone still listening to notebook lm podcasts?