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Posts by Toby Wise

I’m excited to share our new preprint: A Multi-Level Examination of How Hostility Unfolds During Online Argumentation.

osf.io/preprints/ps...

This is the first paper to examine how toxicity manifests from belief differences and how they are represented in the human brain.

1 day ago 11 2 1 1
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Planning in the Brain: It's Not What You Think It Is The neuroscience of planning has long been analogized to search algorithms in artificial intelligence (AI), which simulate future actions to guide immediate choices. We argue that advances in both neu...

New Annual Review with @nathanieldaw.bsky.social: “Planning in the Brain: It's Not What You Think It Is.” We argue that the brain's 'planning' machinery is mostly used for learning from simulated experience, and that thinking prospectively at decision time is just one special case of this process.

14 hours ago 105 46 3 2
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TDLM-Resting-State Simulation How sensitive is TDLM really? Can we actually find replay when we know it is present?

Can we really measure replay in humans using MEG with current methods? In our most recent paper we simulated replay under realistic conditions via a novel hybrid approach with astonishing results.

we're delighted that it has now been published @elife.bsky.social!
elifesciences.org/articles/108...

1 week ago 70 33 3 5
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Computational Psychiatry Conference New Haven, USA (July 14-16, 2026)

📣🔥 Early bird registration now open for 2026 Computational Psychiatry Conference cpconf.org at Yale July 14-16.

Late-breaking abstracts now open (deadline: May 8)

Trainee pre-conference (July 13) registration open (free!)

See you in New Haven! #CPConf2026

1 week ago 30 20 1 0
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📣 So happy to share with you the results of my main PhD study, where two human predators worked together to hunt a human prey in Minecraft, and had their brains scanned simultaneously using fNIRS 🎮🧠

We find that the brains of the predators are synchronised in the prefrontal cortex during hunting! 💡

2 weeks ago 32 9 2 1

🧠 Focused ultrasound changes emotional processing 🔊

In a new study published in Neuron today, we stimulated the human amygdala using transcranial ultrasound stimulation (TUS) and show it plays a causal role in detecting and resolving emotional ambiguity.

2 weeks ago 53 20 1 1
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Computational mechanisms of learning and forgetting differentiate affective and substance use disorders - Molecular Psychiatry Molecular Psychiatry - Computational mechanisms of learning and forgetting differentiate affective and substance use disorders

Congrats to Navid on his new paper in Molecular Psychiatry! Computational modeling found that learning rates and uncertainty sensitivity could distinguish between affective disorders and substance use disorders. Forgetting rate was instead affected transdiagnostically. www.nature.com/articles/s41...

3 weeks ago 12 3 0 0

🚨Last week to apply for a 3 year postdoc with me and @dominikdeffner.bsky.social, embedded in theadaptivemind-excellencecluster.de Focus is on developing innovative experiments and computational models to understand social & cultural learning. Deadline is March 30th 👉 hmc-lab.com/SocialLearni...

4 weeks ago 26 24 0 0
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How is compulsivity related to uncertainty? Inside Neuroscience · Episode

How do we know that things we do will have the outcomes we expect?

We chat to @tobywise.bsky.social about his research into the relationship between compulsivity and uncertainty. Go give it a listen!

#BrainAwarenessWeek

open.spotify.com/episode/2hyj...

1 month ago 5 2 0 0
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💥New paper out! Why do some people generalise threat more than others? We show that anxious people generalise more strongly, even after accounting for perceptual mistakes.

A huge (!) thanks to @ondrejzika.bsky.social @nicoschuck.bsky.social and @bernhardspitzer.bsky.social

1 month ago 48 20 1 4

Thrilled that this first empirical paper out of the lab is posted, led by Sandarsh Pandey, asking:

Depression (and other internalizing disorders) involve profound changes to sense of self. How can we study these differences using rigorous decision-making methods?

(alt link: tinyurl.com/2kk59dje)

1 month ago 83 32 5 1

Last week to apply for a 3yr postdoc with @tsawallis.bsky.social, Frank Jäkel and myself. Deadline is March 15th hmc-lab.com/TAMPostdoc.h...

1 month ago 18 13 0 0

Some nice coverage here of our study published in @biologicalpsych.bsky.social CNNI on structure learning and uncertainty in compulsivity

📃 Paper available here - www.biologicalpsychiatrycnni.org/article/S245...

1 month ago 12 6 0 0

Where you look next isn’t arbitrary.
In our new paper, we model human eye movements in immersive visual search as reinforcement learning under cognitive constraints. 🧵

1 month ago 35 14 1 0

Come work with @tsawallis.bsky.social, Frank Jäkel and myself! 3 yr Postdoc on category learning w/ structured, program-like representations. Funded by the www.theadaptivemind.de Excellence Cluster! Deadline is Mar 15th, details 👇 Please share widely 🙏

1 month ago 15 9 0 1
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a penguin is sticking his head out of a hole next to a job application ALT: a penguin is sticking his head out of a hole next to a job application

🚨 JOB alert: 📢
We are looking for a PhD student to work on our international @wellcometrust.bsky.social project on information gathering in OCD and Schizophrenia!
If you have a background in computational psychiatry / neuroimnaging and speak German, apply here: devcompsy.org/wp-content/u...

1 month ago 20 24 1 0
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Postdoctoral Research Fellow in Social Decision Neuroscience at University of Birmingham Explore an exciting academic career as a Postdoctoral Research Fellow in Social Decision Neuroscience. Don't miss out on other academic jobs. Click to apply and explore more opportunities.

We are recruiting! Postdoctoral research fellow at www.sdn-lab.org, studying the computational & neural basis of social decision-making. Birmingham is a fantastic & affordable place to live, with one of the youngest populations in Europe & over 600 parks. Please share!
www.jobs.ac.uk/job/DQO275/p...

2 months ago 36 45 1 1
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Finally out!! This paper comes from my undergrad work and marks my very first fMRI project.

Here we use mouse tracking and fMRI to show how repeated moral decisions are shaped by the trade-off between reward and consistency, and how the brain adapts to this conflict over time.

3 months ago 0 1 1 0

🚨Four postdoc positions at the #ReasonableAI excellence cluster @tuda.bsky.social!
jobs.rhein-main-universitaeten.de/rmu/job/52370
Please share widely 🙏

2 months ago 8 7 0 0

I have a fairly old and not particularly good one if it would be helfpul?

2 months ago 1 0 1 0
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Linking subjective experience of anxiety to brain function using natural language processing Abstract. Research on anxiety focuses on clinically relevant behaviours and neurophysiological responses, particularly emphasizing recruitment of amygdala,

Our latest work on the neurobiology of subjective emotional experience in anxiety is out now in SCAN 🧠 Brief summary below 👇 doi.org/10.1093/scan...

2 months ago 34 8 1 1
IMPACT-MH: Clinical and behavioral fingerprints of psychopathology – IMPACT-MH

🌟 Job alert! We are looking for a postdoc to join a multidisciplinary research team working on the Individually Measured Phenotypes to Advance Computational Translation at Yale (IMPACT-Y) study.
postdocs.yale.edu/posts/2026-0...

2 months ago 12 9 1 0

Very happy to see our ice-fishing paper on the cover of @science.org this week! 🎣🎉

We tracked large groups of Finnish competitive ice-fishers to study how social foragers use social information when searching for resources. 🐟

Link: www.science.org/doi/10.1126/... (contact me for open access)

2 months ago 94 42 4 2

Now online in @biologicalpsych.bsky.social CNNI - our paper showing that reliance on habitual responding in transdiagnostic compulsivity may be underpinned by uncertainty about learned environmental structure

📃 www.sciencedirect.com/science/arti...

3 months ago 19 7 0 0
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🎉 My PhD work has just been published in @natcomms.nature.com!

How do we learn who caused what - and how much control we had - when outcomes depend on multiple people? We studied how humans do so using a new social learning task, computational modelling and fMRI.

www.nature.com/articles/s41...
🧵👇

3 months ago 53 19 1 2
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Very happy to see this out now in @nathumbehav.nature.com - kudos to @magdadelrio.bsky.social who has led this work and nicely brought together data from two very different studies!
article is here: doi.org/10.1038/s415...
and PDF is here: rdcu.be/eZ27x

3 months ago 26 10 2 0
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RA jobs in Oxford working on a Wellcome Trust funded grant. Neuroimaging, neurostimulation, computational modelling-- what's not to like!

my.corehr.com/pls/uoxrecru...

3 months ago 4 5 1 0

How do we achieve few-shot generalization? New work led by @fabianrenz.bsky.social dives into the role of replay in learning and using structure to generalize reward. Dream team effort with Shany Grossman @nathanieldaw.bsky.social Peter Dayan & @doellerlab.bsky.social
www.biorxiv.org/content/10.6...

3 months ago 74 26 0 1
Gender and anxiety reveal distinct computational sources of underconfidence | Psychological Medicine | Cambridge Core Gender and anxiety reveal distinct computational sources of underconfidence - Volume 56

Our new paper on different types of underconfidence in relation to anxiety symptoms and gender out now in Psychological Medicine 😊
doi.org/10.1017/S003...
with @smfleming.bsky.social

3 months ago 7 6 1 0
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Antidepressant treatment shouldn't be a guessing game. RELMED is working towards using advanced research to predict which medication is most likely to help each person along their individual path to recovery.

Postdoctoral research position in #ComputationalPsychiatry and #EEG as part of relmed.ac.uk trial testing reinforcement learning as biomarker for antidepressant treatment response. www.ucl.ac.uk/work-at-ucl/... @uclbrainscience.bsky.social @mikebrowning.bsky.social @relmed.bsky.social

4 months ago 32 29 1 1