FOX 12 Oregon facebook post screenshot. Headline reads "Latest Updates: 2 more arrested near Portland ICE facility Saturday." Picture shows people outsid the ICE facility in blow-up costumes, L-R: Squidward, Mr. Potato Head, not sure but it's a diapered person in a trucker hat, Garfield, again not sure, banana, lobster
Portland is showing the way. Hail Portland
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8 months ago
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And they said we can’t agree on anything these days!
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“May we embody a new creation where each one of us shares the gifts that we have received.”
César García, the General Secretary of Mennonite World Conference
#MennoGathering2025
9 months ago
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I have one that’s a little charging STAND. Less likely to get jostled.
10 months ago
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Let me be clear:
This isn’t bullying. This is public health education.
This is science.
This is fact-checking dangerous misinformation from someone who now holds power over our nation’s health policies.
Silencing doctors who speak out is not safety—it’s censorship.
I will NOT be silenced.
10 months ago
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“Do not mock us.”
11 months ago
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There is no “debate” about fluoride in toxicology, medicine or science. I don’t think anyone who is capable of basic critical thinking has any problem understanding. These freaks could just not buy toothpaste with fluoride but instead they very badly want to make toothpaste inaccessible to everybody
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This adds to the literature showing restrictive abortion laws increase infant mortality. Don’t let them lie about being “pro-life” when their policies literally kill women and children.
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We could not become like God, so God became like us.
God showed us how to heal instead of kill, mend instead of destroy, love instead of hate, live instead of long for more.
When we nailed God to a tree, God forgave.
And when we buried God in the ground, God got up.
- Rachel Held Evans
1 year ago
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Just to be clear, autistic people who can’t work or date or throw a baseball (?) still deserve to exist and have dignity and worth
1 year ago
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Jewish Groups and Synagogues Defend Students Detained by ICE
More than two dozen are joining a legal effort to free a Tufts University student the Trump administration is trying to deport because of her pro-Palestinian views.
American Jews are opposing the Trump administration's authoritarian actions against pro-Palestinian students who are being falsely accused of antisemitism: "Jewish Groups and Synagogues Defend Students Detained by ICE" www.nytimes.com/2025/04/12/u...
1 year ago
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RFK believes that he is one of the genetic elect and that it is a violation of the natural order to either impose on the genetic elect with public health OR prevent nature from taking its course with those who are predestined to biological damnation.
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ABSTRACT
Lasso peptides (biologically active molecules with a distinct structurally constrained knotted fold) are natural products that belong to the class of ribosomally synthesized and post-translationally modified peptides.
Lasso peptides act on several bacterial targets but none have been reported to inhibit the ribosome, one of the main targets of antibiotics in the bacterial cell.
Here we report the identification and characterization of the lasso peptide antibiotic lariocidin and its internally cyclized derivative lariocidin B, produced by Paenibacillus sp. M2, which has broad-spectrum activity against a range of bacterial pathogens. We show that lariocidins inhibit bacterial growth by binding to the ribosome and interfering with protein synthesis.
Structural, genetic and biochemical data show that lariocidins bind at a unique site in the small ribosomal subunit, where they interact with the 16S ribosomal RNA and aminoacyl-tRNA, inhibiting translocation and inducing miscoding.
Lariocidin is unaffected by common resistance mechanisms, has a low propensity for generating spontaneous resistance, shows no toxicity to human cells, and has potent in vivo activity in a mouse model of Acinetobacter baumannii infection.
Our identification of ribosome-targeting lasso peptides uncovers new routes towards the discovery of alternative protein-synthesis inhibitors and offers a novel chemical scaffold for the development of much-needed antibacterial drugs.
Lariocidin, a lasso-shaped peptide with promising antibiotic properties. (Graphic: Dmitrii Travin and Yury Polikanov). Research: A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome.
Lariocidin hits drug-resistant bacteria where others fail- by hijacking the ribosome at a new site, bypassing defenses, and opening the door to a new generation of antibiotics.
The study has been published in Nature. YES, it is PEER-REVIEWED.
• www.nature.com/articles/s41...
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THIS IS HUGE! Researchers at McMaster University have discovered a NEW peptide antibiotic that targets a broad range of disease-causing bacteria INCLUDING those RESISTANT to existing antibiotics. This discovery marks the first potential new class of antibiotics in NEARLY 30 YEARS. 🧪🧵⬇️
1 year ago
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Exclusive | FDA’s Top Vaccine Official Forced Out
In his resignation letter, Dr. Peter Marks cited ‘misinformation and lies’ from Health and Human Services Secretary RFK Jr.
JUST IN: The FDA’s top vaccine official, Dr. Peter Marks, has been pushed out. In his resignation letter, he slams RFK Jr. for rejecting “truth and transparency” and pushing “misinformation and lies.” Marks warns of an “unprecedented assault on scientific truth.”
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Illegal dumping grounds off the New Jersey turnpike across from Manhattan in the 1970s
Smog rolling on over Manhattan in the 1970s
This is what many cities in the U.S. looked like before the EPA.
Why the heck would anyone celebrate deregulating it?
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Alina Habbard posted: NOTHING CAN STOP THIS MAN FROM FIGHTING FOR HIS COUNTRY.
David Simon had a succinct 2-word response: “Bone spurs.”
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Criminalizing protest is a hallmark of authoritarian regimes
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My online life as a climate scientist ⬇️
2 years ago
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