Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function - Nature Communications α/β-hydrolase domain-containing protein 11 (ABHD11) is a mitochondrial hydrolase, and its expression in CD4 + T-cells has been linked to remission status in rheumatoid arthritis. Here the authors repo...

Ecstatic to share out latest research looking at the role of mitochondrial ABHD11 in controlling T-cell responses. We think this may be a viable target for autoimmunity. Please do give it a read, we would love to hear your thoughts.

www.nature.com/articles/s41...

Congratulations Lydia, Hannah and all the team - such a lovely story 🥳

🦠 New in Discovery Immunology: Obesity impairs dendritic cell (DC) function during viral infection by disrupting cytokine production and metabolism.

A must-read on how metabolic health shapes immune defence. 👉 bit.ly/3Z5ar9K #Immunology

We are witnessing the destruction of science in America | Paul Darren Bieniasz If we stay on this administration’s course, future life-saving medicines may never be invented

We are witnessing the destruction of science in America | Paul Darren Bieniasz www.theguardian.com/commentisfre...

Thanks to global immunisation efforts, an estimated 154 million lives have been saved over the past 50 years 🌎 🤝

That’s equivalent to 6 lives every minute.

#CelebrateVaccines

Obesity is associated with increased susceptibility to infection, which may be due to obesity-induced immune dysregulation. The latest article exchange highlight from @discovimmunol.bsky.social looks at dendritic cell responses to Sendai Virus in a mouse model of diet-induced obesity.

Can you please add me? Thank you!

#SaveTheDate The Irish Society for Immunology meeting will be held on 21/22 August this year in Galway Please Share widely @maynoothuni.bsky.social @ucc.bsky.social @ucddublin.bsky.social @qubelfastofficial.bsky.social

Obesity drives dysregulation in DC responses to viral infection AbstractIntroduction. Obesity is a worldwide epidemic, with over 1 billion people worldwide living with obesity. It is associated with an increased risk of

#Immunity | #Immunometabolism | #DCs | #Obesity drives Dysregulation in Dendritic Cell Responses to #Viral #Infection |

OPEN ACCESS Study from @andyhogan82.bsky.social & pals now at @discovimmunol.bsky.social

Delighted to contribute to this study! Obesity can drive dysregulation in DCs - Congrats to all the @obesityimmunology.bsky.social team 🥳

Thanks so much !

Absolutely delighted to receive this award from
@researchireland.bsky.social
as Highly Commended in the Early Career Researcher of the Year 2024! I'm so grateful to all of my colleagues &the wider research community for their support. Looking forward to continuing our research in 2025 & beyond!