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Posts by Luca Pezzullo

Your dignity honors the bravery of the Ukrainian people.

Be strong, be brave, be fearless.
You are never alone, dear President Zelenskyy.

We will continue working with you for a just and lasting peace.

1 year ago 73754 14744 1619 704
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A foundation model of transcription across human cell types - Nature A foundation model learns transcriptional regulatory syntax from chromatin accessibility and sequence data across a range of cell types to predict gene expression and transcription factor interactions...

A new large language of life model (LLLM) for the transcriptome that predicts gene expression within and across human cell types www.nature.com/articles/s41... @nature.com
For more on the remarkable surge of LLLMs see erictopol.substack.com/p/learning-t...

1 year ago 186 52 1 5
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Working paper studying freelancers argues AI creates an "inflection point" for each job type.

Before that, AI boosts freelancer earnings (web devs saw a +65% increase). After, AI replaces freelancers (translators saw -30% drop). They suggest that once AI starts replacing a job, it doesn't go back.

1 year ago 83 10 5 7
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“Through the screen, I found something unexpected: the chance for technology to offer a different — and sometimes deeper — interaction with patients.”
—@helenouyang.bsky.social
@nytopinion.nytimes.com
gift link www.nytimes.com/2024/12/27/o...

1 year ago 172 46 9 5
"Any moment might be our last.
 Everything is more beautiful
 because we're doomed. You will
 never be lovelier than you are now.
 We will never be here again."

"Any moment might be our last. Everything is more beautiful because we're doomed. You will never be lovelier than you are now. We will never be here again."

A message for our time from Homer’s Iliad.

1 year ago 1821 326 44 19
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‼️"o1-preview demonstrates superhuman performance in differential diagnosis, diagnostic clinical reasoning, and management reasoning, superior in multiple domains compared to prior model generations and human physicians."

And this is using vignettes, not multiple choice. arxiv.org/pdf/2412.10849

1 year ago 76 16 5 3
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Human behavior happens at a surprisingly slow 10 bits/second or so, even though our sensory systems gather 8 orders of magnitude more data. Plus, we can only think about one thing at a time. We don’t know why

(In LLM terms, human behavior happens at less than a token/sec). arxiv.org/abs/2408.10234

1 year ago 122 13 10 2
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Basically think of the o3 results as validating Douglas Adams as the science fiction author most right about AI.

When given longer to think, the AI can generate answers to very hard questions, but the cost is very high, it is hard to verify, & you have to make sure you ask the right question first.

1 year ago 186 36 7 3
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Among ~9 million Americans, representing over 440 occupations, who had the lowest proportion of #Alzheimer's disease related deaths?
Ambulance and taxi drivers
www.bmj.com/content/387/...
? benefit of spatial and navigational processing

1 year ago 273 52 17 17

Endlessly terrible news cycle around this company. Previously:

Can A.I. Be Blamed for a Teen’s Suicide? www.nytimes.com/2024/10/23/t...

An AI companion suggested he kill his parents. www.washingtonpost.com/technology/2...

1 year ago 72 36 7 2
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Just a reminder that none of the people who make LLMs, no matter how smart, actually know what specific tasks LLMs will be good or bad at. We are barely benchmarking these systems at all on any sorts of tasks.

You should explore in areas of your expertise to try to figure it out for your use cases.

1 year ago 196 29 6 6

"Quantity", when at sufficient high levels, becomes "Quality" (a change in the underlying processes): Generative AI produces functional and operational changes in this way.

1 year ago 1 0 0 0

Thank you for sharing.

1 year ago 1 0 0 0

Perfect explanation :-)

1 year ago 2 0 0 0

Very interesting work, @maxboot.bsky.social About 40 years later, the GOP is deeply different...

1 year ago 0 0 1 0

Yes, measure the middle of one piece (folding it on itself), then put them in line, and put on fire the first one. When the flames reach the middle of the second one, 45 minutes have passed...

1 year ago 0 0 0 0

Perfect 😅

1 year ago 0 0 0 0

Very good observation from @emollick.bsky.social : the technical / procedural competence and the functional / context-focused one are on different levels, in LLM use cases...

1 year ago 2 0 0 0

So, this result seems to confirm the previous observations: general LLM frontier models produce similar results, in terms of quality, as medically adapted ones when used in medical field...

1 year ago 3 0 0 0
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These open questions are absolutely valid also for the AI impact on Psychological practice...

1 year ago 2 0 0 0

Just wait until conspiracy theorists discover they’re part of a conspiracy to use conspiracy theorists to spread disinformation via conspiracy theories.

1 year ago 158 25 5 1

The "Personal Tutor" use case is one of the most powerful LLM application to date.
It has the potential to substantially restructure and innovate the Education field.

1 year ago 0 0 0 0
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Like ‘old Twitter’: The scientific community finds a new home on Bluesky After recent changes to Elon Musk’s X, a gradual migration turns into a stampede

Scientific communities are shifting their own "Ideas & News exchange forum" from X to Bluesky... and seemingly with a rapid pace.

www.science.org/content/arti...

1 year ago 0 0 0 0
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I mostly agree.

It’s definitely an escalation and designed to send a message to Kyiv

No, it’s not nuclear armageddon

Ukraine doesn’t have exoatmospheric interception capability, but they do have some terminal phase interceptors that may (heavy emphasis on may) be of some use vs Russian IR/ICBMs.

1 year ago 1040 153 18 1

Very interesting theme... at the intersection of economics, technological development / innovation, and societal dynamics...

1 year ago 1 0 0 0

I would like to be added. Military psychology, cognitive security, stratcom / disinformation.

1 year ago 1 0 1 0
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Interesting, but this isn't the first time...

1 year ago 0 0 0 0

Frankly embarassing... 🙄

1 year ago 0 0 0 0
Screenshot of an Irish Times article from 2011 with the headline "University in talks with Egypt over future of ancient mummy"

Screenshot of an Irish Times article from 2011 with the headline "University in talks with Egypt over future of ancient mummy"

Screenshot of an Irish Times article from 2003 with the headline "UCC keeping 2.3 tonnes of uranium in basement store"

Screenshot of an Irish Times article from 2003 with the headline "UCC keeping 2.3 tonnes of uranium in basement store"

The fact that UCC hid a 3000-year-old mummy under the floorboards of a lecture theatre on a campus where two and a half tonnes of uranium rods were being stored in a basement nearby and DIDN'T end up with a zombie-pharaoh apocalypse is both a mystery and endlessly disappointing

1 year ago 2489 684 66 56