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Posts by Dang Liu

New preprint led by Hrushikesh Loya, me, and Simon Myers where we introduce GhostBuster! www.biorxiv.org/content/10.6...

The idea is to find all the different ways a target individual relates to reference groups in genealogies, to "bust the ghosts" in our ancestry.

1 day ago 35 19 1 1

Inferring hominin history with recurrent gene flow from single unphased genomes and a two-locus statistic www.biorxiv.org/content/10.64898/2026.04...

1 week ago 10 5 0 1
Flyer with information about the Genetics & Neurobiology of Language summer course at Cold Spring Harbor, held on July 27th to August 3rd 2026, applications due by April 10th 2026.
Instructors are Simon Fisher from the Max Planck Institute for Psycholinguistics, Netherlands, David Poeppel from New York University and Kate Watkins from the University of Oxford, UK.
The course description is as follows:
Why are children able to acquire highly sophisticated language abilities without needing to be taught? What are the neurobiological and neurophysiological processes that underpin human speech and language, and how do they go awry in developmental and acquired disorders? Which genetic factors contribute to this remarkable suite of human skills, and are there evolutionary precursors that we can study in other species?
This unique CSHL course, in its sixth iteration, addresses these core questions about the bases and origins of speech and language, through talks, interactive sessions, keynotes and debates, involving leading experts from a range of disciplines. It integrates the state-of-the-art from complementary perspectives, including development, cognitive models, neural basis, gene identification, functional genomics, model systems and comparative/evolutionary studies.
The invited speakers are:
Jennifer Below, Vanderbilt University
Elika Bergelson, Harvard University
Esti Blanco-Elorrieta, New York University
Jonathan Brennan, University of Michigan
Karen Emmorey, San Diego State University
Evelina Fedorenko, MIT
Julia Fischer, Cognitive Ethology Laboratory, Germany
Tecumseh Fitch, University of Vienna, Austria
Adeen Flinker, NYU Langone
Timothy Gentner, University of California, San Diego
Liberty Hamilton, UC Berkeley
Catherine Hobaiter, Wild Minds Lab, University of St. Andrews, UK
Sonja Vernes, The University of St. Andrews, UK
Sandra Waxman, Northwestern University
For funding opportunities and additional course information, please go to: meetings.cshl.edu/courses

Flyer with information about the Genetics & Neurobiology of Language summer course at Cold Spring Harbor, held on July 27th to August 3rd 2026, applications due by April 10th 2026. Instructors are Simon Fisher from the Max Planck Institute for Psycholinguistics, Netherlands, David Poeppel from New York University and Kate Watkins from the University of Oxford, UK. The course description is as follows: Why are children able to acquire highly sophisticated language abilities without needing to be taught? What are the neurobiological and neurophysiological processes that underpin human speech and language, and how do they go awry in developmental and acquired disorders? Which genetic factors contribute to this remarkable suite of human skills, and are there evolutionary precursors that we can study in other species? This unique CSHL course, in its sixth iteration, addresses these core questions about the bases and origins of speech and language, through talks, interactive sessions, keynotes and debates, involving leading experts from a range of disciplines. It integrates the state-of-the-art from complementary perspectives, including development, cognitive models, neural basis, gene identification, functional genomics, model systems and comparative/evolutionary studies. The invited speakers are: Jennifer Below, Vanderbilt University Elika Bergelson, Harvard University Esti Blanco-Elorrieta, New York University Jonathan Brennan, University of Michigan Karen Emmorey, San Diego State University Evelina Fedorenko, MIT Julia Fischer, Cognitive Ethology Laboratory, Germany Tecumseh Fitch, University of Vienna, Austria Adeen Flinker, NYU Langone Timothy Gentner, University of California, San Diego Liberty Hamilton, UC Berkeley Catherine Hobaiter, Wild Minds Lab, University of St. Andrews, UK Sonja Vernes, The University of St. Andrews, UK Sandra Waxman, Northwestern University For funding opportunities and additional course information, please go to: meetings.cshl.edu/courses

“An absolute highlight of my career so far. Academically, I was challenged, provoked, & inspired. I loved how much discussion & thought we packed in, broadening my outlook on the study of language.” Kind words from an alumnus of our summer course. Apply by April 10: meetings.cshl.edu/courses.aspx...

3 weeks ago 26 7 1 2
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Genetics and culture are deeply intertwined. Does your field have something to say about this vast topic? Wanna learn more about the latest research on this?
Join us for this SMBE satellite meeting in Sardinia!

Travel grants are available!
More info here: sites.google.com/view/gene-cu...

1 month ago 10 4 0 0

A biobank-scale method for learning modulators of gene-environment interaction underlying human complex traits from multiple environmental exposures www.biorxiv.org/content/10.64898/2026.03...

1 month ago 0 2 0 0
Original post on ecoevo.social

Excited to share our new preprint on time-lagged F2-statistics, which informs about migration rates from ancient DNA data. Find a preprint here: www.biorxiv.org/content/10.64898/2026.03...

The work was driven by Giulio Isacchini and Oskar Hallatschek. Proud to be part of it! […]

1 month ago 15 10 0 2

Nice to see this out! Great work by Kiran Kumar and Sebastian Zöllner!

1 month ago 7 3 0 0
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Interbreeding between Neanderthals and modern humans was strongly sex biased Sex biases in admixture and other demographic processes are recurrent features throughout human evolution. For admixture between Neanderthals and anatomically modern humans (AMHs), sex bias has been p...

Many living people carry fragments of Neanderthal DNA, remnants of ancient interbreeding events, with uneven distribution across chromosomes. New work by @sarahtishkoff.bsky.social lab suggests patterns are most consistent with Neanderthal contribution to human populations being highly male biased.🧪

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@pratikkatte.bsky.social and I just released Lorax 🌲, a tool for interactive exploration of biobank-scale ancestral recombination graphs (ARGs).

If you’ve ever wanted to scroll across the ancestries of thousands of genomes… this is for you.

1 month ago 39 26 2 0
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Demographic and genetic factors shape the epitope specificity of the human antibody repertoire against viruses - Nature Immunology Patin and colleagues present a mineable Resource database for identifying demographic and genetic factors that impact antiviral antibody repertoires in humans.

Happy to share our last study on how age, biological sex and genetics affect not only the extent of antibody responses against viruses but also the specific viral epitopes recognised. Thanks to Axel Olin @EtiennePatin @LabExMI @institutpasteur @cdf1530 @CNRS

www.nature.com/articles/s41...

2 months ago 28 17 1 2

We are seeking two students: One would develop computational methods for the analysis of ancient DNA from sediments, and apply these tools to novel datasets. The second would generate and analyze aDNA data from archaeological sediments at a number of Holocene sites.

2 months ago 4 3 1 0
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Pygenstrat: A Python package for EIGENSTRAT data processing AbstractMotivation. Ancient DNA studies rely heavily on the EIGENSTRAT genotype format (.geno, .ind, .snp) for standard population genetic analyses includi

@dilekopter.bsky.social

2 months ago 6 5 0 0
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🚨 6th HAAM-RADIO Webinar
🌍 African Population Demography and Social Organizations of the Past
🗓️ Wed, 28 Jan 2026
Register here:
👉 forms.gle/FuBTTX4wreW4...

#AncientDNA #HumanGenetics #AfricanHistory #HAAM #Webinar
@abinstitute.bsky.social @cesarforteslima.bsky.social
@hildegunnink.bsky.social

2 months ago 16 12 2 1
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Genomic and morphometric evidence for Austronesian-mediated pig translocation in the Pacific Several millennia of human-mediated translocation of non-native pig species (genus Sus) to the islands of Wallacea and Oceania have considerably altered local ecosystems. To investigate the timing and...

Starting off 2026 in a highly porcine manner. The story dropped on Jan 1 when a lot of the planet was focussed more on a hangover cure (myself included), than on the latest in human-pig research. Huge congrats to the dozens of amazing scientists and hooray for pigs!

www.science.org/doi/10.1126/...

3 months ago 13 3 0 0

Oh, look! A paper about the coolest piece of software I've ever built!

3 months ago 11 6 0 0

And we're live, Lecture A1 is online. Introduction to Bayesian workflow, generative models, estimands, estimators, estimates, error checking, beginnings of probability theory and Bayesian updating. www.youtube.com/watch?v=ztbY...

3 months ago 199 64 2 5
Portail Emploi CNRS - Offre d'emploi - Postdoc in human evolutionary genetics and bioinformatics (M/F) Assurez-vous que votre profil candidat soit correctement renseigné avant de postuler

📢 We're hiring a postdoc (33 months) in human evolutionary genomics / paleogenomics / statistical genetics, Paris 🇫🇷
Project on selection on disease-associated variants, integrating ancient genomes, GWAS, and Ancestral Rec. Graphs.
Start May 2026 (flexible).
Apply here: emploi.cnrs.fr/Offres/CDD/U...

3 months ago 30 34 2 3
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Observability of mutation rate histories from ancestral recombination graphs This post explores mathematical aspects of recovering mutation rate histories from an ancestral recombination graph (ARG) Vs a sample frequency spectrum (SFS), expanding on a recent collaborative pape...

How much better is an ancestral recombination graph (ARG) than a site frequency spectrum (SFS)? For recovering mutation rate history, we can answer fairly precisely because both ARG and SFS are linear transforms of mutation rate history. This blog post uses spectral analysis to clarify the picture.

3 months ago 14 7 0 0

demografr: A toolkit for simulation-based inference in population genetics www.biorxiv.org/content/10.64898/2025.12...

4 months ago 11 9 0 1

The Influence of Demographic History and Genetic Architecture on Complex Traits via Runs of Homozygosity www.biorxiv.org/content/10.64898/2025.12...

4 months ago 10 3 0 0
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Determining the driving factors shaping genetic architecture of complex traits in recently admixed populations Understanding the genetic architecture of complex traits in admixed populations remains challenging due to heterogeneous genetic backgrounds and demographic histories. Mischaracterizing admixture can ...

Preprint online right before the holidays! Excited to share the first piece of work from the Zhang Lab, led by my absolutely stellar postdoc Michelle Kim! In this work, we ask how admixture, selection and demography shape complex trait genetics and GWAS performance www.biorxiv.org/content/10.6...

4 months ago 44 21 1 0
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A curated global dataset of social contact between diverse language communities

www.nature.com/articles/s41...

4 months ago 25 14 0 0
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Causal modelling of gene effects from regulators to programs to traits - Nature Approaches combining genetic association and Perturb-seq data that link genetic variants to functional programs to traits are described.

GWAS has been an incredible discovery tool for human genetics: it regularly identifies *causal* links from 1000s of SNPs to any given trait. But mechanistic interpretation is usually difficult.

Our latest work on causal models for this is out yesterday:
www.nature.com/articles/s41...
A short🧵:

4 months ago 186 83 3 1
course schedule as a table. Available at the link in the post.

course schedule as a table. Available at the link in the post.

I'm teaching Statistical Rethinking again starting Jan 2026. This time with live lectures, divided into Beginner and Experienced sections. Will be a lot more work for me, but I hope much better for students.

I will record lectures & all will be found at this link: github.com/rmcelreath/s...

4 months ago 662 235 12 20

Work from my amazing undergrad @leyan-wang.bsky.social is just preprinted! TL;DR: If you worry that ARG methods might fail on unphased data due to phasing errors, you may not need to.

Check it out & consider reposting to support a great young scientist!

4 months ago 20 12 0 0

The preprint from my first postdoc is finally out! I had a blast working on this project with such an amazing team!

4 months ago 3 3 0 0
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What enables human language? A biocultural framework Explaining the origins of language is a key challenge in understanding ourselves as a species. We present an empirical framework that draws on synergies across fields to facilitate robust studies of l...

Origins of language, one of humanity’s most distinctive traits, may be best explained as a unique convergence of multiple capacities each with its own evolutionary history, involving intertwined roles of biology & culture. This framing can expand research horizons. A 🧵 on our @science.org paper.🧪1/n

4 months ago 206 86 6 10
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The 2026 EMBL symposium 'Reconstructing the human past using ancient and modern genomics' is live with a fantastic invited speaker lineup!

Abstract deadline 9 June. If work is ongoing, plan for Heidelberg in September😉.

Organised by Maanasa Raghavan, @matejahajdi.bsky.social, Choongwon Jeong & me.

5 months ago 29 19 1 0
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Genomic Investigations of Spoken and Written Language Abilities: A Guide to Advances in Approaches, Technologies, and Discovery Purpose: The aim of this tutorial is to show how the rise of molecular technologies and analytical methods in human genetics yields exciting new ...

If you're interested in how advances in human genomics are transforming our understanding of the biology of spoken & written language abilities, please do check out my new peer-reviewed "tutorial" article, just published.
🗣️🧬🧪
[Will also make a Bsky explainer 🧵 on it next week when I get some time🙂.]

5 months ago 18 10 0 0