Advertisement · 728 × 90

Posts by Debby Silver

Thanks Giorgia! Let us know what you think

1 month ago 1 0 0 0

Thanks so much!

1 month ago 0 0 0 0

Thank you!!

1 month ago 1 0 0 0

Thanks so much Cedric!

1 month ago 1 1 0 0

Delighted to share that our study is now out @cp-cellstemcell.bsky.social www.cell.com/cell-stem-ce... Congrats to Dr. @federicamosti.bsky.social for the culmination of a beautiful thesis!

1 month ago 50 20 3 0
Pathway to Independence programme | Development | The Company of Biologists Pathway to Independence programme | Development | The Company of Biologists Development's Pathway to Independence programme Launched in 2022, Development’s Pathway Independence programm...

There's still time to apply to be a 2026 @dev-journal.bsky.social Pathway to Independence fellow

For those about to apply for their first independent academic position, the programme offers

- mentoring
- leadership training
- profile rising
- networking

journals.biologists.com/dev/pages/pi...

3 months ago 23 34 0 1

heads up neuro bsky 😎 must-read seminal discoveries:

ultimate translation of genetic information in the farthest reaches of the neuron ➡️ @erin-schuman.bsky.social

& in cortex development ➡️ @debbysilver.bsky.social

thanks again 🤝 @natrevneuro.nature.com Darran Yates for editorial collaboration

5 months ago 4 3 0 0
Advertisement
Salt & Whiskey - Horton Grand Hotel Serving elevated comfort foods and classic handcrafted cocktails, Salt & Whiskey at the Horton Grand Hotel pays homage to grandeur of the Victorian era.

At Sfn? Join us at the Cajal Club Social! Sunday, Nov. 16th, 6:30PM–8:30PM. Salt & Whiskey bar@Horton Grand Hotel, www.hortongrand.com/dine-bar. We will learn about an exhibition on Cajal's Work and give out this year's awards to outstanding trainees and established scientists in our community!

5 months ago 6 3 0 0
Preview
Intraspecific sequence variation and complete genomes refine the identification of rapidly evolved regions in humans Humans exhibit significant phenotypic differences from other great apes, yet pinpointing the underlying genetic changes has been limited by incomplete reference genomes and a reliance on single assemb...

“Intraspecific sequence variation and complete genomes refine the identification of rapidly evolved regions in humans”
New work on HAQERs, by
@rimangan.bsky.social Yanting Luo Craig Lowe @debbysilver.bsky.social @manoliskellis.bsky.social & colleagues
🧪🧬

www.biorxiv.org/content/10.1...

6 months ago 13 6 0 0

Thanks so much Keri!!

6 months ago 1 0 0 0

Thanks!

6 months ago 1 0 0 0

Thanks so much Kathy!

6 months ago 0 0 0 0

Thanks! Enjoying working together and looking forward to more collaboration!

6 months ago 1 0 0 0

Thanks so much! We are excited about it and hope it is broadly useful.

6 months ago 2 0 0 0

Thanks Matt!

6 months ago 1 0 0 0
Advertisement

Grateful for funding from NINDS which made this possible!!! And for our outstanding team and collaborators including Phoebe Lee, Lucas Serdar, Stephany Perez-Sanchez, Virginia Fernandez, and @borrell-lab.bsky.social.

6 months ago 4 0 0 0

Finally, we develop a new CRISPR-based method for spatial and temporal manipulation of mRNAs. We hope our tool will propel new discoveries across cells of the nervous system.

6 months ago 4 0 1 0

Our study highlights conserved and unique principles of mRNA localization across the nervous system, and associated with neurodevelopment disease. This generates new hypotheses about functions of radial glia. From this we discover Dynein components control radial glia morphology and interneurons.

6 months ago 6 1 1 0

Radial glia have complex morphologies that are critical for their function. Yet, how they are subcellularly controlled to dictate cortical development remains largely elusive. We discover over 800 transcripts sub-cellularly enriched in radial glia basal compartments.

6 months ago 4 0 1 0
Post image

I am thrilled to share our latest story led by the incredibly talented Brooke D’Arcy and Camila Musso. We discover a rich world of local gene expression in radial glia, essential neural and glial precursors, and develop a new method for sub-cellular mRNA manipulation. www.biorxiv.org/content/10.1...

6 months ago 74 24 4 3

Thanks @blibep.bsky.social for hosting me in Marseille and sharing your exciting science on cerebellar evolution!!
Thanks as well to @alexbaffet.bsky.social and @sbaulac.bsky.social for hosting me in Paris!! What a treat to visit with and discuss fantastic science with all! #internationalscience!

7 months ago 9 0 0 0
Post image

From RNA to evolution: Come join our next keynote lecture on the choreography of brain development by @debbysilver.bsky.social, Professor at Duke University!

📍September 15 at 11am in NQ105 in Martinsried
Art by @somedonkey.bsky.social

7 months ago 6 2 0 0
Advertisement
Video

"What I would simply say is cancer can't wait." --Richard Schlueter, a 56-year-old metastatic cancer patient whose therapy was delayed due to terminations at NIH.

8 months ago 125 82 2 6

Thanks Mariah!

8 months ago 1 0 0 0

Thanks Matt!!

8 months ago 1 0 0 0

Thanks Madeline!!

8 months ago 0 0 0 0
Post image

Grateful to additional fantastic co-authors including
@jingliu1129.bsky.social , Katie Lam, Samantha Skavicus, Nick Heaton, Victoria Kapp. Also enormously grateful to funding from NIMH which made our discoveries possible.

8 months ago 2 0 0 0

Finally in a fantastic collaboration with Katie Pollard and Katie Gjoni, we discover nearby structural variants that stabilize its chromatin loops with these target genes, suggesting co-evolution of human-specific DNA changes.

8 months ago 2 0 1 0

It influences neurogenesis by controlling expression of two key target genes, ETV5 and TRA2B, through a positive feedback loop.

8 months ago 1 0 1 0