It's out, everyone. It's out!
Julia is one of the most brilliant translational methodologists I know, and it was a real honor to work with her on this paper.
Please let us know if you have any questions or feedback!
(BTW, I'm a psychologist now?)
Figure 3D from DOI: 10.1016/j.bbrc.2017.02.118. Six panels are shown showing salmon/pink colored 'blobs' (like oil drops on the surface of a broth) and smaller brownish pinkish cells in random patterns. Each panel is labeled differently. I have added rounded boxes in different colors to highlight overlapping / duplicated areas. Lots of those boxes!
*How *not* to handle image manipulation*.
Editors, please do not address this level of photoshopping with a correction.
In 2020, I flagged Figure 3D of this 2017 BBRC paper. Multiple regions appeared reused within or across panels.
pubpeer.com/publications...
#ImageForensics
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What if you got to work with some of your best friends on a science project? I can't publish how fun this was, but I can show you the data (🧵)! Last week, we posted our second neutrophil swarming paper to bioRxiv and I wanted to post my favorite videos here~
www.biorxiv.org/content/10.6...
1/ Philipp Mallm from the @dkfz.bsky.social Single-cell Open Lab just broke the news at #AACR26: the first results on colorectal cancer (CRC) tissue analysis with the new Atera spatial transcriptomics platform from @10xgenomics.bsky.social. Is it "making the impossible possible?" 🧵
So, OpenAI, whose entire business model relies on some overhyped dudebros using vast amounts of stolen data and stolen labour, is releasing a specialised GPT for the life sciences. And naming it, apparently without any sense of irony or self-awareness. Rosalind.
Someone has documented the entire source code for Elite and explained how every line works, plus included deep dives into various functionality. Covers all main versions like BBC Micro, Commodore 64 and NES. You can also play online in browser. elite.bbcelite.com
The only president stupid enough to do it.
If you havent seen this, make sure you read.
Pretty obvious.
As I point out regularly, because FL is one of the most primitive, regressed states in America, you cannot be elected or appointed to any office there unless you’re a thoroughly despicable and corrupt criminal.
Sam Altman: ‘If I Don’t End The World, Someone Far More Dangerous Will’
Sam Altman: ‘If I Don’t End The World, Someone Far More Dangerous Will’
"Iran has been at war with us for 40-some years" is only one step removed from "we have always been at war with Eastasia"
ChromSMF preprint is out!🚀
tinyurl.com/ChromSMF
We often piece together chromatin regulation layer by layer from separate assays. But this can be limiting!
In @arnaudkr.bsky.social's lab, we developed a method to directly study multiple layers on the same DNA molecule! 🧬
What does this unlock? ⬇️
So US/Proxy Forces are currently bombing or threatening to bomb:
Iran
Palestine
Lebanon
Iraq
Yemen
Afghanistan
Russia
Colombia
Cuba
Venezuela
And I’m just wondering how long it took people to realize they were in a world war 80 years ago.
🧵 What does single-cell transcriptomics reveal about individual patients with acute (AKI) and chronic (CKD) kidney 🫘 disease? Can we use it to find new biomarkers? In our new preprint 👇, we asked this using biopsies from 150+ participants from the Kidney Precision Medicine Project.
“We are a defensive alliance, which means that we don’t do military attacks.”
- Finland President, Alexander Stubbs
I’ll translate that for you Donald, it means that NATO countries aren’t your bitches.
Simple information about what the SAVE Act would actually do to American voters. Tens of millions would lose their right to vote unless they spend lots of $$$ and jump through bureaucratic hoops before November.
We warn fellow members of the Muslim community that at some point the GOP would return to demonizing Muslims. The GOP simply rotates their hate depending on need. Their hatred towards Latinos is costing them votes so now it's Muslims. Soon they will be back to LGBTQ, Blacks, women and repeat.
How do immune disease-relevant variants rewire gene regulation in CD4+ T cells?
In a collaboration led by Daniel Schraivogel and Lars Steinmetz at @embl.org, we combined two large-scale CRISPRi screens (4.1M cells) to map the downstream cascades of thousands of SNPs.
Very happy to see this out. 👏 @yinanwan.bsky.social
Bogdan Bintu and team.
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...
Pediatrics & Child Health has been publishing fictional case studies for 25 years and is now "correcting" them to acknowledge they are fictional. I have never seen anything like this.
retractionwatch.com/2026/03/03/c...
Out now on bioRxiv! 🧬🖥️
Dewi Moonen, @anniquec.bsky.social and a team led by Lars Steinmetz and Daniel Schraivogel at EMBL have mapped the downstream regulatory networks of thousands of immune disease-relevant variants in CD4+ T cells
www.biorxiv.org/content/10.6...
🧵 See 👇 our new preprint on shared and organ-specific gene expression programs of fibrotic diseases 🧬
📄 Paper: doi.org/10.64898/202...
📊 Explore the data: organfibrosis.saezlab.org
The brain drain continues – the U.S. has lost arguably its most important scientific awards ceremony:
arstechnica.com/science/2026...
When a US missile killed 160 children, president shits-a-lot claimed Iran stole the missile and fired at the school. When asked why he was the only one making this claim, he said "because I just don't know enough about it".
Go ahead. See if you can make this make sense.
(Source: RB Hubbell)
MYTH: As commander-in-chief, Trump has the authority to take military action. FACT: It is unconstitutional for a U.S. president to declare war without the approval of the Knesset.
Trump’s War On Iran: Myth Vs. Fact https://theonion.com/trumps-war-on-iran-myth-vs-fact/
In Deutschland denken Frauen heute darüber nach, ihre Babys abzutreiben, weil die Wohnung zu klein ist. Keine bezahlbare Wohnung, keine Kinder. Und die CDU will die Partei von Familie und Heimat sein? In den 60er Jahren schuf die CDU "das Wohnungswunder"! Für Adenauer war…
We are are searching a scientific manager for the ZMBH. This position requires a life sciences PhD & excellent German skills, therefore the advertisement is formulated in German. Very good English skills are needed as well. You are welcome to share the ad:
www.academics.de/jobs/wissens...
