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Posts by Pedro J. Goncalves

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1/ One of the issues of fully amortized inference / pretrained simulator-based inference is that you are stuck with the "prior" training distribution. What if you change your mind after training?

In PriorGuide, one of our papers at ICLR this week, we allow the prior to be changed at runtime!

2 days ago 22 8 1 1
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Strong showing from the Gonçalves Lab at COSYNE 2026 👏
Three abstracts accepted, with posters by Hayden Johnson and Karthik Sama, and a talk by Nastya Krouglova.
Check it out here👇
https://www.youtube.com/watch?v=KZMpTeVEmdc&t=2820s

1 month ago 9 1 0 0
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We are super excited to welcome Dmitry Kobak @hippopedoid.bsky.social as a new VIB.AI group leader! The Kobak lab will officially kick off in April at the VIB.AI Ghent hub.

More:
vib.ai/en/news/dmit...

1 month ago 13 3 0 0
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Come and work with us!
We have a PostDoc position at the intersection of ML and Biogeoscience within the TERRA excellence cluster @terra-cluster.org, w/ Senckenberg.
Be part of a great ML and Geo community and use ML to investigate fire and its impact on global vegetation🔥 🌱🌳
www.mackelab.org/jobs/

3 weeks ago 7 4 0 1
Job Vacancy at the University of Nottingham: Research Assistant (Fixed-term) We seek a predoctoral research assistant to join the Humphries’ group at the University of Nottingham on a BBSRC-funded project to study the neural basis of foraging, in collaboration with the groups of Matthew Apps (Birmingham) and Nathan...

Job!

My lab is hiring a pre-doctoral research assistant to work on the neural computations of foraging, seeking common cross-species algorithms. In collaboration with @brainapps.bsky.social & Nathan Lepora.

Closes April 21st

Pls share!

jobs.nottingham.ac.uk/vacancy.aspx...

3 weeks ago 8 10 0 0

Proud to see this fantastic work by my PhD student @anastasiakrouglova.bsky.social on multifidelity SBI out in the world!

1 month ago 14 2 0 0
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Full house today for the Methusalem BioMedAI kickoff!

The labs of @steinaerts.bsky.social, @joanampereira.bsky.social, @ppjgoncalves.bsky.social & Maarten De Vos came together to launch this long-term research program on explainable and generative AI for biomedical discovery.

Let's go!

1 month ago 7 2 0 0
VIB-KU Leuven Center for Neuroscience
VIB-KU Leuven Center for Neuroscience YouTube video by VIB-KU Leuven Center for Neuroscience

🚀 Proudly introducing the VIB-KU Leuven Center For Neuroscience, a merger of the two former VIB research centers VIB-KU Leuven Center for Brain & Disease Research and Neuro-Electronics Research Flanders (NERF)! Our new motto: Bold Science, Real Impact.

www.youtube.com/watch?v=uhaq...

2 months ago 15 7 0 1
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This is the happy face of four researchers embarking on a cool scientific collaboration backed by 7-years of structural financing!

Congrats @steinaerts.bsky.social, @joanampereira.bsky.social, @ppjgoncalves.bsky.social, and Maarten De Vos on your Methusalem grant.

https://tinyurl.com/nvcardzy

3 months ago 16 3 0 0
Bluesky

The work this article is about has recently been published in @natmethods.nature.com ! It was led by @deismic.bsky.social and was a collaboration between the labs of @jakhmack.bsky.social / @mackelab.bsky.social, @philipp.hertie.ai and @ppjgoncalves.bsky.social.

4 months ago 2 1 0 0
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Simulation-Based Inference: A Practical Guide A central challenge in many areas of science and engineering is to identify model parameters that are consistent with prior knowledge and empirical data. Bayesian inference offers a principled framewo...

Simulation-based inference (SBI) has transformed parameter inference across a wide range of domains. To help practitioners get started and make the most of these methods, we joined forces with researchers from many institutions and wrote a practical guide to SBI.

📄 Paper: arxiv.org/abs/2508.12939

5 months ago 35 10 1 3
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New work out today by a collaborative team including @ppjgoncalves.bsky.social! 🙌

Introducing #JAXLEY, a differentiable simulator that brings biophysically detailed neural models into the realm of large‑scale, machine‑learning‑powered optimization.

https://doi.org/10.1038/s41592-025-02895-w

5 months ago 6 1 0 0

Super excited about this work led by the one and only @deismic.bsky.social!

5 months ago 10 3 0 0
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An ion channel omnimodel for standardized biophysical neuron modelling Biophysical neuron modeling is an indispensable tool in neuroscience research, with the combination of diverse ion channel kinetics and morphologies being used to explain various single-neuron propert...

“Mapping ion channel function” doi.org/10.7554/eLif... isn’t exactly a citation slayer, but it’s still one of my favourites (& my first independent project). Today we push pt 2, where we trace code origin & unite almost all channel models in a common expression. Boom! www.biorxiv.org/content/10.1...

6 months ago 48 16 0 3

From hackathon to release: sbi v0.25 is here! 🎉

What happens when dozens of SBI researchers and practitioners collaborate for a week? New inference methods, new documentation, lots of new embedding networks, a bridge to pyro and a bridge between flow matching and score-based methods 🤯

1/7 🧵

7 months ago 29 16 1 1

Super exciting work led by @bconfavreux.bsky.social and @tpvogels.bsky.social!

10 months ago 7 0 0 0
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The @ppjgoncalves.bsky.social lab is recruiting a PhD student via the VIB.AI International PhD Call 2025!
Join to develop machine learning tools for neuroscience, focusing on simulation-based inference & neural circuit modeling.

📍 Leuven
🗓️ Apply by June 22 → https://tinyurl.com/53nc9vnd

11 months ago 2 3 0 0
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VIB.AI International PhD Call 2025 The VIB.AI International PhD Call 2025 is now open. We invite applicants from around the world to join an interdisciplinary research environment at the interface of AI, computational biology, and life...

Fantastic PhD opportunities at the intersection of machine learning and biology. Come join us at @vibai.bsky.social! More details at: vib.ai/en/vibai-int...

11 months ago 3 4 0 0

Fantastic opportunity to establish your lab in ML for biology! Come join us!

11 months ago 4 1 0 0
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Postdoc position: Computational methods for neurodegeneration research - VIB About the labs The Verstreken Lab and the Gonçalves Lab are based in Leuven, Belgium and part of the

Exciting project in Parkinson's disease! Patrik Verstreken's lab (verstrekenlab.sites.vib.be) and my lab are looking for a postdoc to develop and apply ML methods to the analysis of exciting brain-on-chip data. Please spread the word!

More details at: jobs.vib.be/j/110908/pos...

11 months ago 16 8 0 0
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Hayden, Karthik & Nastya from the @ppjgoncalves.bsky.social lab joined the #SBI Hackathon in Tübingen in March, contributing to the open-source SBI package. Nastya gave a lightning talk on multifidelity inference for computationally expensive simulators. A great week of science & collaboration!

1 year ago 5 1 0 0

Thanks so much for the shout-out, and congrats on your exciting work!! 🎉 🙂

Also, a good reminder to share that our work is now out in Cell Reports 🙏🎊

⬇️

www.cell.com/cell-reports...

1 year ago 36 10 1 0
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We apply our masked VAE approach to drosophila 🪰walking behavior, a macaque 🐒reach task & a synthetic dataset with access to the ground truth.

We propose calibration checks to evaluate the models’ uncertainty estimates, to avoid making confidently wrong predictions.

Check out the paper for more 🙂

1 year ago 5 1 1 0
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Pull requests · sbi-dev/sbi sbi is a Python package for simulation-based inference, designed to meet the needs of both researchers and practitioners. Whether you need fine-grained control or an easy-to-use interface, sbi has ...

It's been a blast, thanks to @sbi-devs.bsky.social ! This week's hackathon was phenomenal! 🙏 😍 The sbi hackathon welcomed about 25 people in Tübingen with contributions spanning the globe , e.g. 🇺🇸🇯🇵🇧🇪🇩🇪. Wanna see, what we did? Check out the PRs👇
github.com/sbi-dev/sbi/...

1 year ago 14 6 0 0
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New work co-led by @ppjgoncalves.bsky.social introduces a powerful new approach to model conditional distributions of neural and behavioral data using masked variational autoencoders.
Congratulations to @auschulz.bsky.social‬ et al.
www.cell.com/cell-reports/fulltext/S2...

1 year ago 24 8 0 0
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1) Some exciting science in turbulent times:

How do mice distinguish self-generated vs. object-generated looming stimuli? Our new study combines VR and neural recordings from superior colliculus (SC) 🧠🐭 to explore this question.

Check out our preprint doi.org/10.1101/2024... 🧵

1 year ago 44 17 1 1

🎉 Just in time for the end of the year, we’ve released a new version of sbi!

📦 v0.23.3 comes packed with exciting features, bug fixes, and docs updates to make sbi smoother and more robust. Check it out! 👇

🔗 Full changelog: github.com/sbi-dev/sbi/...

1 year ago 27 6 1 2
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2024: A Review of the Year in Neuroscience Feeling a bit wired

Cutting it a bit fine, but here’s my review of the year in neuroscience for 2024

The eighth of these, would you believe? We’ve got dark neurons, tiny monkeys, the most complete brain wiring diagram ever constructed, and much more…
Published on The Spike

Enjoy!

medium.com/the-spike/20...

1 year ago 190 72 7 18
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1/ Excuse me, can I interest you in eliciting your beliefs as flexible probability distributions? No worries, we only need pairwise comparisons or rankings, no personal details.

Led by **Petrus Mikkola** and joint with **Arto Klami**, to be presented soon at @neuripsconf.bsky.social #NeurIPS2024

1 year ago 69 14 2 0
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SBI Discord Server 🤖 · sbi-dev sbi · Discussion #1318 Dear all, we are launching an SBI Discord Server! 🎉 We want to use this server to further build a community around SBI, i.e., for sharing insights, questions and events around SBI in general and th...

We are launching an SBI Discord Server! 🎉

We want to use this server to further build a community around SBI, i.e., for sharing insights, questions and events around simulation-based inference in general and the sbi package in particular.

You are all invited to join! 🤗 github.com/sbi-dev/sbi/...

1 year ago 15 6 0 2