Transcriptional repression of central spindle factors controls endomitosis in the C. elegans intestine During development, many cell types transition from canonical to non-canonical cell cycles, suchas endomitosis and endoreplication, in which they duplicate their DNA but do not divide, giving rise to ...

I'm excited to share our work on the regulation of endomitosis in worm intestines:
www.biorxiv.org/content/10.1...

We find that cells are able to uncouple nuclear division from cell division by transcriptional repression of key cytokinesis regulators

Transcriptional repression of central spindle factors controls endomitosis in the C. elegans intestine www.biorxiv.org/content/10.1101/2025.08....

It's possible to apply for the Hubrecht Talent Program again!
The HTP aims to promote scientific excellence in the Netherlands by supporting talented minority students in pursuing a career in scientific research.

Read more in the flyer and on www.hubrecht.eu/about-us/hub...

Plasticity of mitotic cyclins in promoting the G2–M transition | Journal of Cell Biology | Rockefeller University Press The study reveals that individual mitotic cyclins’ roles are more flexible than previously thought. Deficiency of B-type cyclins inhibits mitotic entry, le

doi.org/10.1083/jcb....

We challenged our researchers to describe their work in 10 words or less. See how they did in this video!