Expression level of anti-phage defence systems controls a trade-off between protection range and autoimmunity - Nature Microbiology The authors examine several defense systems and find that increased expression enhances their protection range, albeit at a cost of autoimmunity.

Expression level of anti-phage defence systems controls a trade-off between protection range and autoimmunity
By Nitzan Aframian and Avigdor Eldar.
www.nature.com/articles/s41...

Regulation of a phage defence island by RptR, a novel repressor that controls restriction–modification systems in diverse bacteria Abstract. Bacteria encode a panoply of defence systems to overcome phage infection. In recent years, over 100 defence systems have been identified, with th

Thrilled to see our paper out now in @narjournal.bsky.social: a new transcriptional repressor, RptR, that regulates type I restriction-modification systems! 🎉

Big thanks to the Tang lab (Chris Tang, Rachel Exley), @schullerm.bsky.social, @ahellab.bsky.social and Tim Blower!

doi.org/10.1093/nar/...