Structural Insights into Complement Inhibition: Visualizing Distinct Binding Modes of C4b-binding Protein Complexes with C4b and SAP C4b-binding protein (C4BP) is an innate immune inhibitor found in serum. Human C4BP adopts spider-like higher-order structures (HOS) formed by disulfide-linked C4BPα and C4BPβ chains that non-covalent...

🕷️ Spiders from our blood 🕷️
Check out our new paper from @hecklab.bsky.social describing how the spider-like immune regulator C4BP interacts with its native binding partners.
🔗 www.mcponline.org/article/S153...
#MassSpec #StructuralBiology

Mass Spectrometry Technology Specialist, Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie, Warszawa Job offer Mass Spectrometry Technology Specialist, Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie, Warszawa

🤩 JOB ALERT 🤩 Come work with me and two cutting-edge LC-MS/MS systems at our brand new Mass Spectrometry Facility @iimcb.bsky.social in Warsaw! Apply here tinyurl.com/y47mzafa or send any questions my way. #TeamMassSpec please share widely!

interested in how structural MS integrates with AFM? check out the amazing Tereza's poster at #ASMS2025!

Spiders from our blood 🕷️
Excited to present our work with @hecklab.bsky.social at #ASMS2025 WP 611.

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