Function & cytoarchitecture don't overlap ... they're orthogonal. Prefrontal cortex is plastered with chains of functional patches previously mostly known from face processing. Why multi-modal parcellations are wrong ... and other insights hidden by group-averaging of fMRI data. great explainer👇🏻
Posts by Nico Dosenbach
I always assumed that brain function had to line up with cytoarchitectonics.
It turns out I was wrong.
Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams.
www.biorxiv.org/content/10.6...
Whoa - epic thread and remarkable collaboration! Can't wait to read. #neuroskyence
- NYU's @realjoshsiegel.bsky.social & @ndosenbach.bsky.social
- @camneuro.bsky.social's @estamatakis.bsky.social
+ others from @iupsychbrain.bsky.social
And finally, also check out this piece by @sarahashemi.bsky.social for @smithsonianmag.bsky.social:
www.smithsonianmag.com/smart-news/h...
Function & cytoarchitecture don't overlap ... they're orthogonal. Prefrontal cortex is plastered with chains of functional patches previously mostly known from face processing. Why multi-modal parcellations are wrong ... and other insights hidden by group-averaging of fMRI data. great explainer👇🏻
grpahical abstract
"Intralaminar thalamus relays basal ganglia output to the insular cortex to drive tic generation" spkl.io/63326A4yaA
Yoshihisa Tachibana & colleagues
@cp-cellreports.bsky.social
The number of NIH competitive awards is down 50% from 2025, and down ~70% from prior years. Even if they catch up by the end of the year, only wealthy institutions can bridge these huge funding gaps.They're killing science-and violating the constitution-by weaponizing the bureaucracy
Very interesting paper…
This is going to be my conversation starter at #ohbm2026 @ohbmofficial.bsky.social
Aging reorganizes human large-scale brain networks, with consequences for cognition & dementia risk. We’ve now mapped brain network changes over a wide range of the mouse lifespan. The changes mirror key features of human aging, but not entirely
New @pnas.org paper🧵
www.pnas.org/doi/10.1073/...
Trump's newly announced council of scientific advisors is a startling departure from precious PCASTs: Instead of academic researchers or industry scientists, nine out of 13 members are billionaires, who have a combined wealth of over $900 billion.
My reporting:
Awesome work by @crosenthal.bsky.social's team:
Dear neuromodulation enthusiasts!
Please join us at OptoDBS 2026, which will take place at the Campus Biotech in Geneva, Switzerland, from June 10th to 12th: www.optodbs.ch
Please Repost for reach – thank you!! 🙏🙏
🚨 Want to work at @nature.com with me? We have an ultra-rare opening on my team of reporters.
This reporter, based in NYC or DC, would cover physical sciences, energy, environment, Al and policy.
You'd get to work with some of the most talented editors in the biz! DM w/ any Qs.
Apply by March 20!
@nature.com published a very important study last week: it should that an intervention to educate unmarried adolescent girls in 18 communities in northern Nigeria reduced rates of child (ie under 18) marriage from 86% to 21%. Read more here: www.nature.com/articles/s41...
You've seen place cells, grid cells, mirror neurons,
now...
huddle cells!
Neurons in the rodent frontal cortex (dorsomedial region) appear to track huddling from the cold
and much more detail in this impressive Nature study:
www.nature.com/articles/s41...
Big news: @nature.com has finally launched its TikTok page!
Check out my colleagues Maren Hunsberger with a deep dive on artificial lungs and @shamini.bsky.social talking about an acoustic robot so small it could swim around inside your body.
Follow us for much more content to come 🫶
GLP-1 medications are tied to benefits for cardiovascular health, but the metabolic whiplash from stopping or even pausing the drugs can quickly cut into those gains. Read how much even a short interruption affects the risk to heart health. medicine.washu.edu/news/stoppin...
Have you heard about the primacy of movement over sensation? Why is action the ultimate source of knowledge?
Check it out in our brand new episode with none less than György Buzsáki here:
stimulatingbrains.org/76-gyorgy-bu...
To be clear: If you funnel thousands of scientists into a massive, broad grant pool, but use "agency priorities" or geography to decide who actually gets the money, it's true that bottom-up science becomes top-down quickly
Both are true: fewer targeted NOFOs, more political influence on grants
My attempt to explain-like-I'm-5 the OMB apportionment fiasco - how did I do?
Update 3/16: A very small handful of NIH apportionments have come through — with big exceptions.
The ones that OMB has approved are all Congressionally mandated/earmarked. The broad discretionary funds that fund most NIH grants not yet been authorized.
(1/2)
New lab preprint!
Human Navigation Behaviour and Brain Dynamics in Real-world Contexts
with co-authors: @pfvelasco.bsky.social and @antoinecoutrot.bsky.social
arxiv.org/pdf/2603.11347
It's pi day 3.14 ... I don't know any of the other digits but Nelson Dellis knows 10,000 of them
Read how he does it doi.org/10.64898/202...
And then read how you can do it too with his upcoming book "Everyday genius: Hacks to Boost Your Memory, Focus, Problem-Solving, and Much More"
The 6x US memory champion – Nelson Dellis – can memorize a deck of cards in 40 seconds and knows the first 10K digits of pi.
To figure out how, he let us peak inside his brain. Here is what we learned in our precision brain mapping study www.biorxiv.org/content/10.6...
youtube.com/shorts/MryMq...
Most of what's known about human memory stems from H.M., who had his hippocampus removed bilaterally. So we studied memory champion Nelson Dellis with precision brain mapping. Everyone's memory for numbers is crap ... 10 digits. He's memorized 10,000, by turning it into a skill, more like juggling
Honestly this is so cool bsky.app/profile/rose...
I build a feed for european grant funding that's updated daily and (IMO) far more transparent then the official EU fundign website: michelnivard.github.io/eu-grants-fe... (inspired by the NIH equivalent @sashagusevposts.bsky.social build yesterday)
Selective DBS-induced deactivations in the SCAN, building on our recent @nature.com paper.
Thrilled to announce our new paper in @natneuro.nature.com!
We managed the impossible: precision functional mapping during #DBS, with 11.7h fMRI/patient.
Selective DBS-induced deactivations in the SCAN, building on our recent @nature.com paper.
nature.com/articles/s41...
@ndosenbach.bsky.social
Roselyne is job-shopping, too. I wish WashU could keep her!