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Posts by Lisa Giocomo

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Hippocampal place code plasticity in CA1 requires postsynaptic membrane fusion Rapid delivery of glutamate receptors to the postsynaptic membrane via vesicle fusion is a central component of synaptic plasticity. However, it is un…

New paper! Congrats to @markplitt.bsky.social, Konstantin and team! The brain’s spatial map isn’t static but for hippocampus CA1 maps to change with experience, they need postsynaptic membrane fusion. A new link between synaptic machinery and flexible coding!

www.sciencedirect.com/science/arti...

2 weeks ago 34 9 0 3

Great papers in spatial neuro this week. Csicsvari's group: hippocampal place fields stabilise during learning while mPFC stays flexible. Giocomo's lab: CA1-subiculum topography actively shapes boundary coding & corner cells.

doi.org/10.64898/2026.03.27.714523
doi.org/10.64898/2026.03.24.714092

2 weeks ago 16 3 0 0

Congrats @emilyaeryjones.bsky.social and team! The brain doesn’t just map where you are, it maps where it matters. Great thread below!

2 weeks ago 18 2 1 0

New preprint! Circuit wiring isn’t just anatomy, it shapes computation. Disrupting CA1→subiculum topography reorganizes spatial coding and destabilizes network dynamics. Great collab led by Yanjun Sun, & with D Pederick, X Xu & L Lou!

www.biorxiv.org/content/10.6...

3 weeks ago 4 0 0 0
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Spatial navigation in preclinical Alzheimer's disease: A review

New review from @antoinegc.bsky.social and @antoinecoutrot.bsky.social labs, on which I am a co-author, and first author is the amazing Syrine Salouhou

arxiv.org/abs/2603.23082

3 weeks ago 30 8 0 0
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Fun afternoon with the lab learning how to make homemade pasta!

3 weeks ago 0 0 0 0
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State-dependent spatial maps for navigation Internal behavioral states influence many brain circuits, with well-known effects in sensory areas. Less is known about how these states shape downstr…

Really enjoyed writing up this article with Lavonna Mark for @cp-trendscognsci.bsky.social on how internal states - like attention, arousal, or goals - can reshape our brain's map of space, helping the brain adapt navigation to what matters most.

www.sciencedirect.com/science/arti...

1 month ago 21 7 0 0

Anyone else running into NPX 2.0 supply issues? Heard there’s a 90 pause on accepting new orders 🫣

2 months ago 0 0 1 0
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Sunrise run in NYC @rockefeller.edu

3 months ago 2 0 0 0
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Holiday brunch with the lab! Grateful for this community of creative and thoughtful scientists!

4 months ago 6 0 0 0
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On Sunday, I tried to follow my own advice! Born with hip dysplasia, and starting to run in 2019, I never imagined I would run a 3:40 marathon or BQ. I’m deeply grateful to the family and friends who supported me along the way and continue to inspire me! It’s never too late. We can do hard things ❤️

4 months ago 11 0 1 0

I often tell my students that graduate school is a marathon—pace yourself, refuel consistently, and build a strong support team.

4 months ago 8 0 1 0
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Summer Undergraduate Research Experience | HHMI The Cech Fellows Program is a paid, nine-week summer research experience empowering the next generation of scientific leaders.

Calling all rising juniors & seniors: Interested in biological or biomedical research? Applications for our ’26 Summer Undergraduate Research Experience Program are now open! Nine weeks, hands-on research, & mentorship from some of the nation’s top scientists — learn more: bit.ly/CechFellows

5 months ago 70 89 0 12
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Had a blast with the lab and friends at #SFN2025 in San Diego!

5 months ago 5 0 0 0
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At SFN 2025? Come check out our posters on Monday!

5 months ago 4 0 0 0
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Sosa Lab - Postdoctoral Researchers We are seeking postdocs to start in 2026!

The Sosa Lab is going to #SfN25 and actively recruiting ✨postdocs✨ with systems neuroscience experience! We study both fundamental memory processes and how memory changes during pregnancy and postpartum.

If you are interested in meeting at SfN, please email me! www.sosaneurolab.com/join/postdoc...

5 months ago 78 49 1 1

Congrats to lead authors @alexattinger.bsky.social and Tony Drinnenberg and all our amazing collaborators! Check out the thread below for new work from the lab on plasticity, cortex and spatial representations for navigation!

5 months ago 23 3 0 0
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Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement - Nature Neuroscience Hardcastle and Marshall et al. show that striatal function is domain specific, required for task-related but not spontaneously expressed movements. This functional distinction is reflected in starkly ...

Excited to announce that my first postdoc paper is now online!

Links:
www.nature.com/articles/s41...
rdcu.be/eAcN7

In it, we examine the perennial question: what changes in the brain when learning a new motor skill?

Read more below to find out 👇

8 months ago 145 35 9 1

Congratulations!!

8 months ago 1 0 0 0
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A flexible hippocampal population code for experience relative to reward - Nature Neuroscience Sosa et al. find that hippocampal neural activity in mice encodes both environmental location and experience relative to rewards, spanning distances far from reward, through parallel and flexible popu...

It's officially published!! In my main postdoc work with @markplitt.bsky.social and @lgiocomo.bsky.social, we found that the hippocampus simultaneously encodes an animal's spatial position and its experience relative to reward in parallel population codes. 🧵

www.nature.com/articles/s41...

10 months ago 128 40 9 0

New paper from the lab officially out! Congratulations @marisosa.bsky.social - amazing work - and just before she sets off to UC Boulder to start her own lab!

10 months ago 30 4 0 0

Please re-post and share! This is a great effort to improve communication of science benefits and discoveries

11 months ago 2 0 0 0
Searchable database of tangible benefits that federally-funded research gave us. A crowd-sourced site. Health and Well-being. National Security. Prosperity.

Calling all science advocates!! Carlos Brody+ are creating a searchable database of tangible science benefits, and they need you.

publicusaresearchbenefits.com

They are asking for suggestions - from brief to lengthy. The database is state-searchable, so all 50 states.

Please spread the word!

11 months ago 51 46 1 2
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Early morning run on the High Line ❤️

11 months ago 0 0 0 0

New lab alert!! Mari is an incredibly creative and awesome scientist - plus an amazing mentor! If you have the opportunity to join her lab - I can’t recommend it enough - can’t wait to see her get started ❤️

11 months ago 10 1 0 0
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Looking forward to a day of science at @CSHL! Started my day with a sunrise run - such a beautiful campus

1 year ago 1 0 0 0
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Congratulations to Charlotte Herber on her beautiful thesis defense today! The MD world is very lucky to have you headed back to clinic soon but we will miss you! Excited to see where your future path takes you in research and medicine!

1 year ago 3 0 0 0
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New from the lab!! 👉🏼 authors.elsevier.com/a/1kgT43BtfH... 📝 @cellpress.bsky.social We discovered that genetically-defined neuron types in the hippocampus form unique manifolds! Dual color imaging, chemogenetics and topological analysis all at once! With Juan Gallego @juangallego.bsky.social

1 year ago 90 32 4 3
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Congratulations to John Wen on his thesis defense! Amazing to see what you've accomplished over your PhD and can't wait to see where your journey takes you!

1 year ago 2 0 0 0

We are currently looking for a research scientist/technician!

1 year ago 2 1 0 0