A photo of someone pipetting and the text "Research Scientist to characterise transposon mutant libraries in Shewanella and other relevant organisms. Salary: £37,500 to £30,600, Contract length 1 year, Apply by 7 April 2026"

🆕 Vacancy! We’re looking for a Research Scientist to join @webberma.bsky.social 's group and characterise transposon mutant libraries in Shewanella and other relevant organisms as part of the EB MIND Engineering Biology Mission Award

💷 £37,500 to £40,600
🗓️ Apply by 7 April 2026
➡️ buff.ly/a4OQqYe

Great to hear our local MP Ben Goldsborough highlighting in Parliament the world-class science taking place here at the Quadram Institute and @johninnescentre.bsky.social on vitamin D deficiency and sunshine tomatoes🍅

We’d be delighted to host a visit by Dame Angela Eagle.

Clostridia from preterm infants metabolize human milk oligosaccharides to suppress pathobionts and modulate intestinal function in organoids - Nature Microbiology Clostridium perfringens lacking perfringolysin O toxin isolated from preterm infants metabolizes human milk oligosaccharide disialyllacto-N-tetraose to produce metabolites that promote the growth of c...

🚨 A new piece of the preterm gut microbiome puzzle just fell into place!

Bifidobacterium metabolise human milk oligosaccharides (HMOs) in early life — shaping immunity, supporting gut development, and protecting against diseases like necrotising enterocolitis (NEC).

www.nature.com/articles/s41...

Clinical innovation fund backs new research projects to benefit Norfolk patients - Quadram Institute The Quadram Institute Clinical Seedcorn Fund was first established in 2021/2022 to help clinicians develop research ideas with scientists at the Quadram Institute. The fund supports secondments of…

"It’s great to see @nnuh.bsky.social clinicians working with scientists at the Quadram to understand more about some of the clinical challenges they face daily, and how we can understand and then tackle them for the benefit of patients.”

💬 @dfigeys.bsky.social

A photo of the Quadram Institute with a quadrangle and the text "Group Leader, with a research focus on microbiome, modelling and host-microbe interactions."

⏰ Closing soon! We’re looking for an ambitious and collaborative Group Leader or Career Track Group Leader to pioneer the development of next-generation microbiome assays and model systems

💷 Competitive
🗓️ Apply by 15 February 2026
➡️ buff.ly/W3Sphca

A social card with the text, "Senior Research Scientist Microbiome Assay and Metaproteomics, to support with day-to-day running of the Figeys lab, including line management, overseeing budgets and scientific direction. Salary: £45,450 to £56,750, Contract length: 2 years, Apply by 15 February 2026."

⏰ Closing soon! We are looking for a Senior Research Scientist to support with day-to-day running of @dfigeys.bsky.social lab, including line management of staff, overseeing budgets, and leading the scientific direction.

💷 £45,450 to £56,750
🗓️ Apply by 15 February 2026
➡️ buff.ly/juVfDq7

Senior Research Scientist - Norwich, Norfolk job with Quadram Institute Bioscience | 12852913 Applications are invited for a Senior Research Scientist to join the Laboratory of Prof Daniel Figeys at Quadram Institute Bioscience

Expert in #metaproteomics? Join the Quadram Institute and help us transform functional microbiome research.
#microbiome

www.nature.com/naturecareer...

Exploring #microbiome data? MetaTree makes statistically based hierarchical tree comparisons easy and accessible.

If you have experience in #metaproteomics and microbiology, then this is for you!

A photo of the Quadram Institute building with the text "Group Leader, with a research focus on nutrition and microbiome-based interventions for the prevention and management of obesity. Salary: Competitive, Contract length: Indefinite, Apply by 18 January 2026."

⏰ Closing soon! We are looking for a Group Leader with a focus on nutrition and microbiome-based interventions for the prevention and management of obesity to join our Food, Microbiome and Health research programme as a Group Leader.

💷 Competitive
🗓️ Apply by 18 January 2026
➡️ buff.ly/5CIkq6J

A social card with the text, "Senior Research Scientist Microbiome Assay and Metaproteomics, to support with day-to-day running of the Figeys lab, including line management, overseeing budgets and scientific direction. Salary: £45,450 to £56,750, Contract length: 2 years, Apply by 15 February 2026."

🆕 Vacancy! We are looking for a Senior Research Scientist to support with day-to-day running of @dfigeys.bsky.social lab, including line management of staff, overseeing budgets, and leading the scientific direction.

💷 £45,450 to £56,750
🗓️ Apply by 15 February 2026
➡️ buff.ly/UpcuEPa

Are you interested in #metaproteomics? We have a senior scientist position in my lab focused on metaproteomics, and xenobiotic- #microbiome -host interactions. Check it out.
jobs.quadram.ac.uk/Details.asp?...

New book shares Quadram’s Best Practice in Microbiome Research - Quadram Institute Researchers from the Quadram Institute have developed an open access book to help ensure best practice in microbiome research.

Researchers from the Quadram Institute have come together to develop a new open access book filled with cutting-edge methods and protocols to ensure best practice in microbiome research.

Newsletter - Quadram Institute Our newsletter highlights the latest news and research breakthrough from across the Quadram Institute

Our latest newsletter is out now 📩

Sign up to stay up to get our latest news straight to your inbox ⤵️

Zhang et al, with the #RapidAIM assay and #metaproteomics, show that gut #microbiomes exhibit shared and individualized functional responses when exposed to six structurally distinct oligosaccharides. Functional understanding requires studying in dividual microbiome.
www.nature.com/articles/s41...

“The Quadram Institute is proud to be part of the newly launched National Research Organisations (NRO) Group – uniting UK research centres to #MakingResearchMatter for people, communities & the economy."

💬 Professor @dfigeys.bsky.social

Prebiotics reverse effects of anti-depressants on the gut microbiome - Quadram Institute Scientists from the University of Ottawa and Beijing Institute of Lifeomics found that SSRIs, SNRIs and Tricyclic Antidepressants, commonly prescribed anti-depressants that target the…

🆕 Anti-depressant drugs cause profound changes to the human gut microbiome, but these changes could be mitigated by prebiotics, according to a major new survey of how the microbial community in the gut responds to different therapeutic drugs 💊

@dfigeys.bsky.social
buff.ly/uKd5PDv

Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism Claims that the gut microbiome causally contributes to autism regularly appear in the scientific literature and popular press. Mitchell et al. critically examine influential studies underpinning these...

Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism www.cell.com/neuron/fullt...

Functional redundancy matters: the more overlapping microbial functions you have, the more resilient your #microbiome. We showed a strong negative correlation between redundancy loss and increase in #antimicrobial resistance protein upon #drug treatment of microbiomes.
@quadraminstitute.bsky.social

Interestingly, #drugs for the nervous system (antidepressants/antipsychotics) stand out: #SSRI/ #SNRI/ #TCA push the gut #microbiome into alternate states, lowering functional redundancy(lower capacity to respond) and ramping up antimicrobial-resistance proteins.
@quadraminstitute.bsky.social

A landscape shot of the rooftops of Norwich, with the Cathedral in the centre. In the foreground are trees without their leaves.

1 in 5 people in the UK are estimated to be deficient in #vitaminD during winter and spring 📉

Our ViTaL-D Study aims to understand whether tomatoes biofortified through gene-editing tomatoes to be high in vitamin D leads to higher levels of active vitamin D in the blood 🍅

➡️ buff.ly/SIsELo6

From #drug cabinet → gut #microbiome: screening 312 therapeutic compounds, we mapped 4.6 million microbial protein-level responses to reveal how our drugs don’t just target us, they hit our gut microbes too.

rdcu.be/eMmcT

Systematic metaproteomics mapping reveals functional and ecological landscapes of Ex vivo human gut microbiota responses to therapeutic drugs Nature Communications - Here, the authors systematically map metaproteomic responses of ex vivo human gut microbiota to common therapeutics, identifying several drug classes inducing strong...

Interested in #drugs, #microbiome and #antibiotic resistance, then check out our paper on the effects of over 300 drugs on the gut microbiome. Exciting results as well on the role of antibiotic resistance defining how microbiomes respond to drugs.
@quadraminstitute.bsky.social

rdcu.be/eMmcT

We were delighted to welcome Sir Ian Chapman the new CEO of @ukri.org , together with BBSRC representatives, to Norwich Research Park today hear about our world leading bioscience.

Discover more about our research at the Quadram Institute
➡️ buff.ly/NZYHB2r

Exposure to sugar rationing in first 1000 days after conception and long term cardiovascular outcomes: natural experiment study Objective To examine whether exposure to sugar rationing during early life is associated with a reduction in the risk of cardiovascular outcomes in adulthood. Design Natural experiment study. Settin...

Exposure to sugar early in life: a natural experiment among >63,000 @uk_biobank participants: rationing of sugar was associated with less cardiovascular risk in adulthood www.bmj.com/content/391/...

New technique to speed up the design of drugs targeting proteins in the cell membrane - Quadram Institute An team has developed a new technique that will speed up the design of drugs targeting ion channels, a type of cell membrane protein

“This study is particularly important to me as it took place during my post doc years at the @uniofeastanglia.bsky.social and it has been a source of inspiration for my current research line, as a newly appointed Early Career Fellow at the Quadram Institute."

💬 Dr Serena Monaco

Vitamin D3 concentrations are lowered by common vitamin D supplement - Quadram Institute Taking vitamin D2 might be lowering the body's levels of the more efficient form of vitamin D, vitamin D3, according to new research

“Vitamin D deficiency represents a significant public health concern, especially during the winter months with significant deficiency across the UK population."

💬 Professor Martin Warren, our Chief Scientific Officer

Maternal emulsifier consumption alters the offspring early-life microbiota and goblet cell function leading to long-lasting diseases susceptibility - Nature Communications Here, Delaroque et al. show that maternal intake of dietary emulsifiers alters offspring microbiota early in life, which, associated with perturbation of goblet cell function, promotes increased susce...

Maternal emulsifier consumption alters the offspring microbiota leading to long-lasting diseases susceptibility
www.nature.com/articles/s41...
Consumption of food additives during pregnancy alters offspring gut microbiota and increases inflammatory disease risk
medicalxpress.com/news/2025-09...

This is an exciting position that will shape the direction of how we target the gut microbiome. Come join my lab at the Quadram Institute.

Interested in compound- microbiome interactions, and how they affect health? Join my lab at the Quadram Institute.