⚖️ Pain depends on the balance of excitation & inhibition.
⬆️ Excitation → hyperalgesia, allodynia
⬆️ Inhibition → analgesia
This month’s BJA Education article highlights key mediators: glutamate, GABA, opioids, serotonin, cannabinoids.

👉 www.bjaed.org/article/S205...

Neurophysiology of acute and chronic pain: from genes to pain symptoms As the earliest writings of ancient civilisations attest, pain has been an unceasing challenge for humanity. This sensory and emotional experience is essential if we are to live in good health. It…

🔍 Pain neuromatrix: Melzack’s theory proposes pain emerges from a dynamic network of brain structures.
Below shows sensory, affective & cognitive dimensions.
Not one centre—but a mosaic of systems.
👉 www.bjaed.org/article/S205...

Thanks for this nice exposure of our recent review… the next one in central sensitization mechanisms will be launched in the October edition !

A 5000-year overview of the history of pain through ancient civilizations to modern pain theories. Will it be a must read article ? by Vincenot et al. Great job and thanks to the University of Sherbrooke historians journals.lww.com/painrpts/ful...

Job opportunity🥼
I'm looking for an engineer or junior researcher to work on a project analysing the links between adverse childhood experiences and pain. Previous experience in cellular imaging or electrophysiology +++ contact me if interested. Job located in the beautiful French Strasbourg city

A number of permanent research positions are currently available at the University of Strasbourg: assistant professor (opioid and pain networks), Junior Professor (neurochemistry of pain), Research Chair (open thematic on pain research) .... contact me for more information.

NeuroStra call: Young Group Leader in NeuroPain to develop a project in line with the NeuroPain priority axis

Recruitment of a Young Group Leader in pain research (contact me in private for details). Position is located in Strasbourg France.
Deadline for application: 30 March 2025
Details of the call: neurostra.unistra.fr/en/news/actu...

Pleased to share with you that our French-speaking medical journal has received the 2024 “cover illustration award” from the French medical press. Congrats to our editor John Libbey Eurotext and to the Swiss-Canadian-Belgian-French editorial team

Between Scylla and Charybdis: assessing the... : PAIN voidance place preference paradigm, an integrated testing procedure in freely moving rats that relies on the conflict between the avoidance of a dark compartment in which a thermal ramp is activated, ...

Just landed here! You might find some interest in our recently accepted article in Pain: "Between Scylla and Charybdis: assessing the multidimensional aspects of pain behaviors in rats using a double avoidance place preference paradigm" #pain send comments if any!
journals.lww.com/pain/abstrac...