Once-Adventurous Salmon Can’t Believe She Ended Up Moving Back To Birthplace, Having A Bunch Of Kids

Once-Adventurous Salmon Can’t Believe She Ended Up Moving Back To Birthplace, Having A Bunch Of Kids theonion.com/once-adventurous-salmon-...

Ever seen a reindeer having dreams? Be my guest :) #bliss

Rapid genome modifications including chromosomal fusions and large-scale inversions are key features in Arctic codfish species - Genome Biology Background Genome evolvability involves activation of transposable elements (TEs) that result in novel genomic rearrangements, including translocations, deletions, duplications, as well as larger stru...

Finally is the paper where we present the unique genomic architectures of the Arctic codfishes out!! Nice work by @gadus-sivus.bsky.social and co-authors …
@biovitenskap.bsky.social
@unioslo-cees.bsky.social

link.springer.com/article/10.1...

It's out! I hope this work encourages folks to move beyond a standard "one variant, one gene" QTL paradigm and consider proxitropic variant effects. Big thanks to the reviewers and editors at @ajhgnews.bsky.social for their help! @sbmontgom.bsky.social www.sciencedirect.com/science/arti...

🚨 We're hiring!
Postdoctoral positions in modeling of development and evolution at @stockholm-uni.bsky.social & @scilifelab.se

Focus: dynamical systems, time-series, phylogenetics, dimensionality reduction

📍 Stockholm
🕒 2+1 years
🔍 Details: su.varbi.com/en/what:job/...

Please share!

A pleiotropic hitchhiking model recapitulates alignments between fly wing divergence and variation www.biorxiv.org/content/10.64898/2026.02...

Have you ever wondered 🤔... Does phenotypic variance respond to environmental perturbation? Does it have a genetic basis? Are mean and variance regulating loci exposed to different selection pressures? These and more questions are explored in our new preprint 🔥

www.biorxiv.org/content/10.6...

Preprint alert: We adopt a cheap & rapid WGS protocol for vertebrate sized genomes, and use it to sequence nearly 1K whitefish genomes to low/med coverage for lake-wide pop genomics of adults + larvae for species assignment, habitat use, decline & selection: www.biorxiv.org/content/10.6...

#PopGen

Transgenerational plasticity affects fitness and mediates local adaptation www.biorxiv.org/content/10.1101/2025.11....

Evening views from home, morning views from the office

CDFW: 'Salmon Everywhere' One Year After Klamath River Dam Removal A little more than a year after the historic removal of four hydroelectric dams on the Klamath River, California Department of Fish and Wildlife (CDFW) scientists are seeing salmon reoccupying just ab...

A beautiful story of success amid all the carnage. Turn a river loose and it heals.

CDFW: 'Salmon Everywhere' One Year After Klamath River Dam Removal www.dailykos.com/stories/2025... || #rivers

Genuinely one of the most important and interesting papers I have been a part of! Relevant to fundamental questions regarding the predictability of adaptation, as well as the applications of genomic data. Congrats to @j-smiley-rhodes.bsky.social and all co-authors for such a masterpiece!

North of the Arctic Circle it’s winter wonderland already

Excited to share our review on alternative splicing evolution, with @peterinnes1.bsky.social and Nolan Kane!

Join Us The lab of Nina Overgaard Therkildsen in the Department of Natural Resources and the Environment at Cornell University invites applications for a PhD position starting in Fall 2026. Our group works...

Excited to recruit a new PhD student for Fall 2026 in my lab at Cornell! Looking for someone interested in evolutionary genomics + fisheries/conservation applications. Quick timeline this year—reach out soon. More details: www.therkildsenlab.org/join-us.html

New paper from the lab: we’re using long-read sequencing to disentangle isoform complexity at allele-specific loci 🧬💡
Here, we combine the PacBio Iso-Seq workflow with the established WhatsHap phasing approach to assign long reads to the correct allele in polymorphic F1 mouse hybrids.

Super excited that the bulk of my PhD work is now preprinted! Here we used whole-community competition, or coalescence, experiments to quantify selection acting on genetically diverged strains within larger communities. (1/n)
www.biorxiv.org/content/10.1...

Interested in doing a PhD in how extinction processes can inform conservation? Do you see yourself working at the intersection of genomics, museums, conservation and butterfly biology. If so consider applying for the ILESLA PhD programme at Oxford Brookes: www.brookes.ac.uk/courses/rese...

This was such a shocking thing to hear, even having already been told how bad it was...

Big Biology guest Dr. Katie Lotterhos reads out the banned word list given to a federal scientist. ❌ 😶 📋

Learn more about the impacts of federal and state policies on science since January 2025 by listening to the full episode with Katie: bigbiology.substack.com/p/vulnerabil.... 🎧

#science #bio

Monty Python understood p-hacking

Massively parallel interrogation of the fitness of natural variants in ancient signaling pathways reveals pervasive local adaptation The nature of standing genetic variation remains a central debate in population genetics, with differing perspectives on whether common variants are almost always neutral as suggested by neutral and n...

One of the most exciting works of my career, years in the making. We used high-throughput precision genome editing to test the fitness effects of thousands of natural variants. Our findings challenge the long-held assumption that common variants are inconsequential.

www.biorxiv.org/content/10.1...

They might not be giants: The genetics behind why some fish remain tiny Imagine you are a kind of fish called a goby, part of a huge family of more than 2,000 species. Maybe you're of average size for a goby, about three to four inches long.

Certain goby fish species remain miniature by overexpressing genes that inhibit growth, a genetic mechanism conserved for over 50 million years and shared across diverse vertebrates. doi.org/g97pqp

I'll be reviewing applications for this in a few days, so there's still time to get touch if you're interested.

💥 Another fruitful collaboration!

Along with @obog.bsky.social & Juan Tena’s teams we provide a multiomics study of zebrafish spermatogenesis
🐟#meiosis

👇
www.embopress.org/doi/full/10....

PhD OPPORTUNITY! 🔬🔖

Still one more day to apply for our fully-funded PhD position in Norway!

Please share widely 🙏

Inversions 😊

www.biorxiv.org/content/10.1...

Thank you so much Rob!

One week to apply for our fully funded PhD position in Norway! This is a really exciting project in collab. with University of Helsinki and Benchmark Genetics.

Samples are ready - you do (read: learn) everything - functional genomics, bioinformatics, genotype-phenotype associations 🤩

Please RT!