Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey.
Posts by April Hayes
My main postdoc paper is now out in @natureportfolio.nature.com npj Antimicrobials and Resistance! www.nature.com/articles/s44.... Using flow cytometry, we show that the nucleoside analogues azidothymidine, didanosine, stavudine, and trifluridine reduced transfer of AMR plasmids pCT and pKpQIL (1/3)
LLMs are like your stoner friend who is a voracious reader. They have a lot of information in their brains, but it's not necessarily in the right order, and sometimes they talk utter nonsense.
📢 Excited to be offering a Plant Health vacation studentship this summer on plant disease biocontrol and predatory bacteria! Supervised by me at Manchester Uni! @manchester.ac.uk
If interested—or know someone who might be—please share and apply! my.rsb.org.uk/services.php... 28th April deadline 🌿🍅🦠
would 100% recommend this as a PhD position to anyone interested in bacteria/temperature/amr. Dan is a great scientist to work with, and more importantly is a kind person who cares about people and (also) how science works
New paper showing that bacteria with more genes for cooperation can live in a broader range of habitats and that genes for cooperation are more more likely to be in the accessory genome www.pnas.org/doi/10.1073/... @lauriebelch.bsky.social
Cover of Microbiology Outlooks featuring an article by Dr Damien Meyer on integrating game dynamics with within-host evolution genomics.
Is virulence a fixed trait? This first commentary in Microbiology Outlooks considers why it may be better understood as a context-dependent evolutionary strategy. Discover the Open Access article: https://doi.org/10.1099/mout.0.00001
🚨 New preprint 🚨
How promiscuous really are conjugative plasmids, and what does that mean for plasmid co-occurrence?
A pleasure to collaborate with @craigmaclean.bsky.social on the first paper of my fellowship!
www.biorxiv.org/content/10.6...
📣 2026 PhD studentship 📣
Via @manchester.ac.uk 's President's Doctoral Scholar Awards, we are encouraging applications for a PhD on the effect of pollutant exposure on microbe-immune cross talk. This project will incorporate microbiology, immunology, & bioinformatics. Deadline: 16 March 2026!
He may have only barely known about bacteria, and not at all about viruses, but Darwin was right about hating an ill-defined species concept
The coolest finding of my PhD is finally out! E. coli has a 7th RND pump that is present in phylogroups B2/D/E/F but absent in A/B1/C. As a result EefABC has been absent in all K-12 RND studies! Co-authored by the very talented Dr. Lizzy Darby. @jessicamablair.bsky.social
doi.org/10.1099/mgen...
Delighted to have contributed to this impressive work led by @tovefall.bsky.social & many others👏 (w/ @gazollavolpiano.bsky.social from our side). This novel microbiome GWAS (n=~16k+12k valid) expands knowledge on genetic factors associated w/ gut microbiota variation.
www.nature.com/articles/s41...
Now out & nicely formatted in @isme-microbes.bsky.social
A big analysis of ocean genomes & metagenomes co-led by former postdocs, now PIs, @gmdouglas.bsky.social & @cyanophage.bsky.social along with co-PIs @lbobay.bsky.social & Samuel Chaffron.
A few highlights... 🧵 (1/n)
doi.org/10.1093/isme...
I am pleased to share that our paper is now published in Cell!
www.cell.com/cell/fulltex...
I am deeply grateful to all co-authors for making this possible.
This work was made possible through the guidance of Dr. Peer Bork. I share this in grateful memory and with deep respect for his mentorship.
🚨 PhD Studentship available! 🚨
We're hiring a UK student to start in Oct '26 via the BBSRC CODEM scheme. Full studentship plus £10k top-up PA. Study the mysterious ZOMBIE PHAGES 🧟 🦠 with our fabulous @mermanchester.bsky.social and @uommib.bsky.social communities!
www.findaphd.com/phds/project...
At long last, my final PhD chapter is out: we developed a novel evolutionary simulator of bacterial pangenomes, Pansim, fitting it to data from >600K genomes using a likelihood-free framework, PopPUNK-mod, to explore neutral and adaptive pangenome dynamics www.biorxiv.org/content/10.6...
Historical contingency limits adaptive diversification in a spatially structured environment
@evolletters.bsky.social from @megbehri.bsky.social
academic.oup.com/evlett/artic...
New round of PhD studentships in microbial engineering, including one with me on engineering non-canonical DNA mismatch repair into E. coli 🦠🧬
www.findaphd.com/phds/project...
PhD projects in microbial engineering now up, including one with @whelanfj.bsky.social @willpjsmith.bsky.social and me! 🦠
www.findaphd.com/phds/project...
Thrilled to see this paper finally out! journals.plos.org/ploscompbiol... It was a difficult story to communicate and took us a while to get right. Big congratulations to @wbjorn.bsky.social, Pablo Guridi and Flora Arias-Sanchez!! And thank you the reviewers who helped improve it. Keep reading...
🚨 Fully‑funded PhD for Home Students🚨
We'll explore non-antibiotic alternatives in relatistic environments, uncovering how they work, if they affect antibiotic activity and whether they influcence AMR acquistion. Come join a wonderful supervisory team!
#MicroSky #UTISky #AMar
tinyurl.com/38u552bu
It's easier to tear down than build up, and in science we have a bad case of that. So: how to lead a journal club that actually finds value in what you read. scientistseessquirre... 🧪
"84.9% of colleagues on FTCs reported that their contracts had negative impacts upon their wellbeing"
^ As long as fixed-term contracts (FTC's) are the norm for early-career scholars + many others, then our workplaces are structurally screwing us.
There's still a few days left to apply for our AI-Intervene PhD project mapping the drivers of avian influenza using viral genomics, bird migration data and AI-powered phylodynamics.
Come join us! Details below.
#FindaPhD #LondonPhD #genomics
Our preprint on predicting drug resistance in bacteria is now out in @plosbiology.org. We show ignoring phylogenetic structure in genome collections leads to overly optimistic evaluations of machine learning methods for AMR prediction. Work from @yanyingyu.bsky.social with @nwheeler443.bsky.social.
🦠🧫 a collaboration with the Institute for Tropical Medicine in Tübingen and CERMEL in Gabon @cmfi.bsky.social
Asexuality is a global identity.
That’s a major finding in a study I recently published with @francescorampazzo.com in Demographic Research.
Analyzing dating app data spanning 162 countries from over 900,000 users, we found that asexuality showed up in every age group and in every region.
MetaPointFinder:
A new approach for detecting mutation-driven antimicrobial resistance directly from metagenomic reads.
Fills a major gap in current resistome profiling by capturing chromosomal AMR mutations that metagenome tools miss.
github.com/aldertzomer/...
We're excited to release metaTraits.embl.de! 🦠 Interactively explore 140+ 𝗺𝗶𝗰𝗿𝗼𝗯𝗶𝗮𝗹 𝗽𝗵𝗲𝗻𝗼𝘁𝘆𝗽𝗶𝗰 𝘁𝗿𝗮𝗶𝘁𝘀, harmonized & integrated from culture-derived collections 🔬 & genome-based predictions 🧬 for >2M MAGs & genomes.
Publication at NAR: doi.org/10.1093/nar/... @narjournal.bsky.social #microsky 🧵 1/8
It’s not only medications—environmental chemicals can also inadvertently harm our gut microbes. Excited to have contributed a bit to this important study!