🆕💫 Narrative Review @cmicomms.bsky.social
@jeffpears0n.bsky.social
Tetracyclines, the Old and the New
🔹Tetracycline 1953
✨Doxycycline 1967
🔹Minocycline 1971
🔹Tigecycline 2005
🔹Eravacycline 2018
🔹Omadacycline 2018
#IDsky #EMIMCC
www.sciencedirect.com/science/arti...

What is your meaning to the suffering

I’m a fan so far! It has helped a lot with me paying for attention to form and core strength.

I’m becoming a Pilates believer as much as I hate to admit it.

Thundering snowstorm got me feeling like I’m in The Day After Tomorrow.

2/
Firstly: it sounds obvious, but make sure what you're seeing is actually the IVC! ❗

We've all been fooled by an aorta at least once 🙈

The two vessels can be quite close together; but the aorta will be more medial; it will appear to be straighter, more vertical, and will have thicker walls

Long-Term Oxygen Therapy for 24 or 15 Hours per Day | NEJM To the Editor: In a multicenter, randomized, controlled trial comparing duration of long-term oxygen therapy (24 hours vs. 15 hours) in patients who had severe hypoxemia at rest, Ekström et al. (Se...

Our letter to the editor is out in NEJM in response to this year's REDOX trial! www.nejm.org/doi/full/10....
Can we definitively state there is no disadvantage to 15h versus 24h at 1 year in terms of mortality when NOTT required 2 years and MRC required 5 years to demonstrate a mortality benefit?

Spelling the word Syphillis is always so hard to me.

A

All about nafithromycin, first antibiotic developed in India against deadly, drug-resistant bacteria Developed by Mumbai-based Wockhardt, it will be available under brand name Miqnaf. Administering it once-a-day for 3 days could be significant in addressing drug-resistant pneumonia.

All about nafithromycin, first antibiotic developed in India against deadly, drug-resistant bacteria theprint.in/health/all-a...

Long-Term Aspirin vs Clopidogrel After Coronary Stenting by Bleeding Risk & Procedural Complexity

🦋 Clopidogrel monotherapy was associated with lower thrombotic & bleeding risks

#CardioSky #MedSky
@jama.com
jamanetwork.com/journals/jam...

Eyeballing severity of MR. Best done in PLAX view. Measure the vena contracta (narrowest portion of jet at the mitral valve).
- Mild MR: < 0.3 cm
- Moderate MR: 0.3–0.69 cm
- Severe MR: ≥ 0.7 cm

#POCUS

Cervical cancer mortality in US women younger than 25 years significantly declined between 2016 and 2021, likely due to the widespread adoption of HPV vaccination.

ja.ma/4i9ghPC

three men in military uniforms salute each other ALT: three men in military uniforms salute each other

Adding it promptly to the lexicon, sir

Not a normal part of my diction as I’m pretty yeehaw🤠

Association of Lipoprotein(a) With MACE Independent of hs-CRP: Systematic Review & Meta-Analysis

#JACCAdvances #CardioSky #MedSky
@pnatarajanmd.bsky.social @michaeldshapiro.bsky.social @erinmichos.bsky.social @jaccjournals.bsky.social @accintouch.bsky.social
www.jacc.org/doi/10.1016/...

It’s my birthday so I’m eating cake at 9am

Prophylaxis with Bactrim DS in HIV+ with a CD4+ count 100-200

Effects of Sacubitril/Valsartan on Prevention of Cardiotoxicity in High-Risk Patients Undergoing Anthracycline Chemotherapy - American College of Cardiology Amit Saha, MD

www.acc.org/latest-in-ca...

Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections | NEJM Bloodstream infections are associated with substantial morbidity and mortality. Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. In a multicenter, non...

Feels right that my 1st post here should be to share this incredible RCT, led by my PhD supervisor Nick Daneman:

www.nejm.org/doi/full/10....

Main takeaway: 7-days of abx should be the standard of care for patients with uncomplicated non-S. aureus BSI.

A deep dive 🧵:

#IDsky

Deep thought provoking things going on right now.

Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections | NEJM Bloodstream infections are associated with substantial morbidity and mortality. Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. In a multicenter, non...

🚨 Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections

BALANCE trial publication is here !

#IDsky #Medsky

@idjclub.bsky.social

www.nejm.org/doi/full/10....

Things We Do for No Reason™: Prescribe cefdinir for treatment of common infections Click on the article title to read more.

!
shmpublications.onlinelibrary.wiley.com/doi/abs/10.1...

No false negative paradox in STEMI-NSTEMI diagnosis ST-segment elevation myocardial infarction (STEMI) diagnosis is based on a clinical presentation and ST-segment elevation (STE) in at least two consecutive leads. Despite being deeply rooted in both t...

shortcomings of the STEMI NSTEMI paradigm, resulting patient harm, and why we need to add on the 'OMI paradigm' which i will post next
#CardioSky #EmImCc #12lead #ekg #STEMI #pci #OMI
heart.bmj.com/content/110/...

Thus is so lovely!

This feels like a mixture of LinkedIn and 2016 Twitter