Can hydralazine trigger ANCA vasculitis? — NephJC A large registry cohort was essential to move beyond scattered case reports and finally quantify the true risk of hydralazine‑associated vasculitis. When rare events blur into background noise, only s...

Check out the VA on hydralazine and population vasculitis risk by Dr. Divya Bajpai #NephSky
www.nephjc.com/news/2026/4/hydralazine-anca-va

Why-dralazine?! Population risk of drug induced vasculitis — NephJC This week, we will discuss why a large registry cohort was needed to move past decades of scattered case reports and clarify the true risk of hydralazine‑associated vasculitis. When rare events hide i...

Do you prescribe hydralazine?
Or, do you 🛑 it as soon as you see it?
Hydralazine persists despite TID dosing & risks like... vasculitis 🔥
Are you asking Why-dralazine?
✅The blog by @dramiliflores.bsky.social @nephroseeker.medsky.social
#NephSky
www.nephjc.com/news/hydralazine-anca-vasculitis

#NephJC and @theisn.org Advancing Clinical Trials collab for #Nephtrials

STEPS trial tests coordinated system-level intervention to improve preemptive kidney transplant

🗓️XSpce: April 10, 12pm EST

✍️Blog by @dramiliflores.bsky.social and @nephroseeker.medsky.social
www.nephjc.com/news/steps-n...

Announcing the NephJC Editorial Internship — NephJC Are you a curious, motivated nephrology fellow or early‑career faculty member with a passion for science communication? NephJC is inviting a small group of talented individuals to join our Editorial I...

11/10
Like what you see 👀
Want to join a fun team of FOAMed enthusiasts?
Want to learn more about VAs, Blogs and Podcasts (oh my)!
Applications now open: www.nephjc.com/news/nephjc-editorial-internship
This has been @brianrifkin.bsky.social with a NEW 10 POSTS ✍️

System Interventions to Achieve Early and Equitable Kidney Transplants (STEPS): Protocol for STEPS, a randomized comparative effectiveness clinical trial - PubMed The System Interventions to Achieve Early and Equitable Kidney Transplants Study (STEPS) is an ongoing pragmatic clinical trial investigating the effectiveness of an equitable and patient-centered approach to kidney care on equitable access to early kidney transplants for individuals with chronic ki …

10/10
Final thoughts
🧂Don't be salty, sometimes doing nothing isn't wrong.

➡️Up next- 4/10/26: NephTrials System Interventions to Achieve Early and Equitable Kidney Transplants (STEPS): protocol (www.pubmed.ncbi.nlm.nih.gov/40199386/)
More at www.nephjc.com/

Searchin’ For My Lost Shaker of Salt- Targeted Treatment of Hyponatremia — NephJC This week, we will discuss the HIT trial- a large randomized study challenging one of the most reflexive responses in hospital medicine: see hyponatremia, fix the sodium. But what if correcting the nu...

9/10
I want more info:
He’s here, he’s there he’s every f-ing where Roy Ken..I mean @brianrifkin.bsky.social with the VA and blog:
www.nephjc.com/news/hyponatremia/hit-trial
www.nephjc.com/news/2026/4/4/hyponatremia-correction-the-visual-abstract

8/10
Consensus
“To treat or not to treat?” is a profound question in asymptomatic pts.
The authors conclude that the trial does not suggest “do nothing” for mild/mod ⬇️Na, but rather that intensive treatment does not confer clear benefits in this short study.

7/10
Question 2/3
#NephJC #NephSky
2. Do you think if strategies were followed longer (60 days post hospitalization) that the outcomes may have been different?

3. Would you want to see an exclusively outpatient, protocol driven intervention with outcomes?

6/10
Question 1
#NephJC #NephSky
1. What is your treatment of choice for a hospitalized, asymptomatic mildly hyponatremia (128-134 mmol/L) euvolemic pt?
a. nothing
b. fluid restriction
c. urea
d. vaptan
e. other

5/10
A figure paints🖼️ a 1000 words!
☠️Death occurred in 8% of both groups
🚑13% of intervention & 14% of control pts were rehospitalized
📆The median length of stay (7 days) was similar in both
There were no differences in cognitive assessment, QoL or rates of falls at 30-days

4/10
1 post results
🏥At D/C 56% of intervention & 37% of control pts had normal Na levels
🧮Estimated absolute difference -1.3% (95 CI, -4.9 to 2.2; p = 0.45) b/t groups
⬇️Na recurrence or persistence at 30-days was approximately 41% in both groups

3/10
1 post methods
This is a pragmatic, RCT, parallel-group, multi-center superiority trial with blinded outcome assessment.
Conducted at 9 centers in Europe from 8/2018-4/2024.
University & community based hospitals were included.
(Sorry, can’t resist a good Na joke)

2/10
What'd I miss?
⬇️Na is associated with osteoporosis, falls, fractures, gait disturbance & subtle cognitive impairment. Among patients with mild/moderate hyponatremia it remains unclear if normalization of sodium levels is beneficial.
Want to hear a sodium joke?

1/10
#TenPostNephJC
#NephSky
What do you do with a consult for a hospitalized pt with Na = 131?
“Just chill” 🥶or “Guns a blazin’” 🤠(fluid restrict, urea, vaptan)? Do these strategies improve mortality or re-hospitalization?
Read the article 👇
pubmed.ncbi.nlm.nih.gov/41733398/

0/10
Hey NephJC faithful, we are shaking it up.
Given the 📉 attendance at live chats we’re changing to a summary 🧵& ❓ to answer, at your convenience.
Still tag us #NephJC to get the discussion going!
PS If we hear enough comments, we might bring chats back!😉

a man with a beard and a white shirt says time for the grand reveal ALT: a man with a beard and a white shirt says time for the grand reveal

In jut 1 hour #NephJC is unveiling something new...
#NephSky #MedSky

Regarding the Situation with…Social Media in General — NephJC Regarding the Situation with… Twitter, Bluesky, Social Media We at #NephJC pride ourselves on bringing you the best in nephrology publications and innovations without commercial bias. As we’ve ...

Hey #NephSky #MedSky
📣If you were planning on coming to the #NephJC chat on hyponatremia 4/7/26 at 9 pm...relax, we're trying something new (and it will be on Twitter and BlueSky)!
www.nephjc.com/news/2026/4/7/regarding-the-situation-withsocial-media-in-general

Stopping ADPKD Progression: What We Know & What We Can Do Now Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disorder caused by PKD1/PKD2 mutations, leading to progressive cyst growth and kidney decline. This blog reviews key disease me...

📖Check out the latest @kireports.bsky.social community blog on slowing ADPKD from @thekidneywhisperer.bsky.social

#NephSky #MedSky

www.kireportscommunity.org/post/stoppin...

Searchin’ For My Lost Shaker of Salt- Targeted Treatment of Hyponatremia — NephJC This week, we will discuss the HIT trial- a large randomized study challenging one of the most reflexive responses in hospital medicine: see hyponatremia, fix the sodium. But what if correcting the nu...

🧂Hyponatremia. We see it. We fix it. #NephJC

But what if fixing the sodium… doesn’t fix the patient?
The HIT trial challenges one of medicine’s most reflexive moves

✍️ By @brianrifkin.bsky.social

www.nephjc.com/news/hyponat...

Live Blogging Trials from Conferences — NephJC An interview about our experiment with conference coverage of simultaneously published studies

Do you have #FOMO from missing all the fun at #ISNWCN ?
We've got you covered!!
Check out the interview with
@nephroseeker.medsky.social and @hswapnil.medsky.social
discussing simultaneous publications at WCN in Yokohama, Japan #NephSky
www.nephjc.com/news/conf-coverage

Hiponatremia: El Resumen Visual — NephJC La hiponatremia es uno de los trastornos electrolíticos más frecuentes en pacientes hospitalizados y se asocia de manera consistente con peores desenlaces. Su corrección mejora los valores, pero ¿real...

Hiponatremia el resumen visual, gracias @dramiliflores.bsky.social #NephSky #NephJC

www.nephjc.com/news/2026/4/4/hiponatremia-el-resumen-visual

Hyponatremia Correction: The Visual Abstract — NephJC Hyponatremia is one of the most common electrolyte disorders in hospitalized patients and is consistently linked to worse outcomes. Correcting sodium improves the numbers—but does it improve short-ter...

📉Low asymptomatic sodium in a hospitalized patient:
Are you chill 🧊 or do you treat 🛠️ ?
Next #NephJC 4/7/26, we're changing it up (let's see if anyone notices 👀) #NephSky
VA by @brianrifkin.bsky.social
www.nephjc.com/news/2026/4/4/hyponatremia-correction-the-visual-abstract

NephJC Short: The Push Trial — NephJC Water, water everywhere. Can a wink, a nudge and a push increase water intake to decrease kidney stone formation?

🚨 #NephJC short 🩳from @kidneyboy.bsky.social
The PUSH trial!
😉Can a wink, a nudge & a push encourage kidney stone formers to drink more fluid to prevent recurrence 🪨?
(Hint: have 💦 behavioral trials worked in CHF or PCKD?)
#NephSky #MedSky
www.nephjc.com/news/2026/4/2/nephjc-short-the-push-trial

NephJC Covers LBCTs at the World Congress — NephJC The NephJC editors cover the simultaneous publication from the world congress

Covering the world 🌐 @hswapnil.medsky.social @nephroseeker.medsky.social
🧑‍💻Reporting in from Yokohama, Japan #ISNWCN 🌸
📰Read all about the late breaking news #NephJC #NephSky
www.nephjc.com/news/isnwcn-yokohama

The #ISNWCN has high trial impact clinical trials to celebrate latest and more successful results in our nephro world

To celebrate the joy of getting together, and to #NephItForward, we officially opened up the #NephJC Editorial Internship application

www.nephjc.com/news/nephjc-...

Newsletter — NephJC

👀 We'll soon start looking for a new generation of interns

📍Don't miss out on the #NephJC call

💌 Subscribe to our newsletter

www.nephjc.com/newsletter

4/ Congrats to all finishing the #NephJC internship. I hope each of you leaves richer, personally or professionally.

We’ll close with @nephro_sparks’s words👇

3/ @nephrosparks.bsky.social delivered a powerful reminder of what #NephJC teaches us and what we aspire to.

🫰One line stays with us: persistence beats perfection.

2/ @brianrifkin.bsky.social recap highlighted our progress and future plans, but what stays with me is this: #nephjc never stops adapting. We keep learning, improving, and reaching for a better version of ourselves 🌟

1/ Today’s #nephjc graduation was pure joy. Seeing mentors and interns from around the world come together reminded me why this community matters.

✨Thank you for making it extraordinary