Rethinking How We Provide Guidance When Evidence is Limited Mayar A Mohajer, Michael Klompas, Majdi Al-Hasan, Robert Colgrove, Shira Doron, Thomas File, Natasha N Pettit, Michael Pulia, Sharon Weissman; Rethinking H

Ah sorry I posted the wrong link
This is the correct link
#idsky
academic.oup.com/cid/advance-...

I don't have access 😔
Any quotes will be appreciated #idsky

The 1 outcome was clinical recovery assessed by the Days to Recovery Scale through Day 60 (DRS-60), analyzed using a Van Elteren test #idsky

Ensitrelvir for the treatment of hospitalized adults with COVID-19: an international phase 3 randomized placebo-controlled trial AbstractBackground. Antivirals remain an important treatment strategy for persons who experience severe and life-threatening COVID-19. Ensitrelvir is an or

If you still care about COVID-19
🆕💥🔴Ensitrelvir for the treatment of hospitalized adults with COVID-19: an international phase 3 randomized placebo-controlled trial #idsky
academic.oup.com/cid/advance-...

🆕💥🟢LIPS RCT Protocol: LInezolid Plus Standard of care
12 Swiss hospitals
Linezolid in addition to standard antibiotic treatment for Staphylococcus aureus bacteraemia
More combo /SA Bactremia
Clinda failed in SNAP,will LZD make it?
More combo from SNAP #idsky
bmjopen.bmj.com/content/16/4...

Super proud to be part of the BALANCE+ family 😇

#IDSky

▶️BALANCE PLUS: a platform trial answering challenging questions on Gram-negative infections
Beta lactam oral transition domain
DOOR
#ESCMIDGlobal2026 #idsky

Evidence Over Eminence: Rethinking Specialty Guidelines Amid the ATS-IDSA Debate Brad Spellberg, MD, Bassam Ghanem, PharmD MS BCIDP, Miguel Morante-Ruiz, MD, Émilie Bortolussi-Courval, RN PhD, Anil N Makam, MD MAS, Zeynep Ergenc, MD, Ni

💥Update: Our LTE has prompted a response from IDSA.
"Rethinking How We Provide Guidance When Evidence is Limited"
Looking forward to where this discussion goes next #IDsky
academic.oup.com/cid/advance-...

A sobering but very important observation about war and antibiotic resistance
#IDSky #ClinMicro #AMR

So far SNAP RCTs have confirmed my practices:

1) ✅ cefazolin
2) ❌ clindamycin

#IDSky

IDVYNSO is the first and only non-INSTI, tenofovir-free, once-daily, complete two-drug regimen to demonstrate non-inferior efficacy in a head-to-head Phase 3 trial versus three-drug regimen BIKTARVY®i (BIC/FTC/TAF) #idsky

💥New FDA Approval 💥
FDA Approves Merck’s Once-Daily IDVYNSO™ (doravirine/islatravir) for adults with virologically suppressed HIV-1 with no history of virologic treatment failure and no known substitutions associated with resistance to doravirine #idsky
www.merck.com/news/fda-app...

Evidence Over Eminence: Rethinking Specialty Guidelines Amid the ATS-IDSA Debate Brad Spellberg, MD, Bassam Ghanem, PharmD MS BCIDP, Miguel Morante-Ruiz, MD, Émilie Bortolussi-Courval, RN PhD, Anil N Makam, MD MAS, Zeynep Ergenc, MD, Ni

Proud to be part of this great team led by @bradspellberg.bsky.social
🔥Our LTE is now published
“Evidence Over Eminence: Rethinking Specialty Guidelines Amid the ATS–IDSA Debate.”
A timely discussion on evidence vs eminence in the guidelines development. #IDsky
academic.oup.com/cid/article/...

See you at the next ESCMID Global 2027 Stockholm, Sweden, April 9–13
#ESCMIDGlobal2027
#ESCMIDGlobal2026

Thanks 😊

we should be more infectious 😊

😂

It's really important to amplify , the ID community is very shy, mostly lurking why ? #idsky

No difference in CDAD
Unexpectedly low

A pleasure to serve as a Social Media Ambassador for #ESCMIDGlobal2026
Thank you @ESCMID & the fantastic team behind the meeting
So much knowledge,so many RCTs.
Missed it? Check the hashtag ( ++X & Bsky) for highlights 👀
See you at the next ESCMID Global 2027 Stockholm, Sweden, April 9–13 #idsky

In SNAP Clindamycin
Persistent bactremia was more in Clindamycin group
It's intriguing!
Any thoughts, insights please
#ESCMIDGlobal2026 #idsky

▶️UTI in patients with stones and stents: rocks and hard
LEITNERLorenz, Switzerland
Excellent talk by urology surgeon
🚫JJ stents mimic UTI
JJ stent # Infection
Enterococci👀 #ESCMIDGlobal2026 #idsky #utisky

It increasingly feels like leaving X hasn’t played out as hoped.
Alternative platforms are trying—but the same level of engagement just isn’t there (yet).
Worth acknowledging—and perhaps rethinking! #idsky #ESCMIDGlobal2026

Most of the audience changed their mind to con OH approach
Mine is also towards con
Also prof Walsh con OH

No more distraction
▶️ #ESCMIDGlobal2026 #idsky

▶️Wars have become a breeding ground for lethal drug-resistant bacteria
A shocking example, look at CPE rate increase in NL hospital near Ukraine
#ESCMIDGlobal2026 #idsky

▶️Pro/con debate: is One Health essential or a distraction in AMR related policies
#ESCMIDGlobal2026 #idsky

▶️Pro/con debate: is One Health essential or a distraction in AMR related policies
Humans Ego not Eco
The problem is purely human ?
#ESCMIDGlobal2026 #idsky

▶️Pro/con debate: is One Health essential or a distraction in AMR related policies
#ESCMIDGlobal2026 #idsky

🚨 Late Breaker – PROCALBAN OL RCT
🧪 PCT-guided de-escalation in sepsis (Bangladesh,n=532)
🎯Daily PCT→ stop Abx after 72h if <0.5 or ↓>80%
⏱️ Antibiotic duration nearly halved
• 4.7 vs 9d(p<0.0001)
🛡️ Safety preserved
• ⚰️ No difference in 28d mortality
#ESCMIDGlobal2026 #idsky