Rachel A. Gottschalk @gottschalklab.bsky.social, Satarupa Ganguly @satarupa2025.bsky.social & team show lung macrophages lacking GATA2 during inflammation promote metabolic dysfunction & profibrotic gene expression in mice: doi.org/10.1172/jci....
The four astronauts aboard NASA's Artemis II mission are about to plunge through the atmosphere toward Earth, after a successful visit to the moon. n.pr/4spkBOo
So cool
www.nasa.gov/missions/art...
Pleased to share our recent work out today in @natmetabolism.nature.com. This study addresses a longstanding mystery - NRF2-driven cancers increase cysteine acquisition (via xCT) by ~5x - so where does all that cysteine go?
Zero information in this title
The next iteration of O-MAP targeting genomic loci is now at eLife!!
DNA O-MAP enables proximity labeling at specific DNA loci took a ton of work from many lab members and collaborators, so it's really exciting to wrap up this paper with @oligopain.bsky.social!
elifesciences.org/articles/102...
If dendritic cells are part of your science,
#DC2026 should be part of your year!
🌍Global DC community in San Diego
✳️New biology & discoveries
Abstracts & registration are OPEN
www.dc2026sandiego.com
⭐️ Come for the science. Stay for the community. @maxkrummel.bsky.social @zunigalab.bsky.social 🔁
@ucsdimmunology.bsky.social We have plenty of free parking
Another great speaker @gottschalklab.bsky.social coming to @lji.org. Come join!
HCF1 orchestrates O-GlcNAcylation and affinity-dependent transcription through extended molecular determinants and register-shifted binding www.biorxiv.org/content/10.64898/2026.03...
These figures are gnarly
There's many journals to choose from. There's only one NIH.
Why can’t people (especially scientists) see that AI generated figures and diagrams shout out that they were AI generated and look awful? You’ve spend many months designing and performing experiments only to cover the resulting masterpiece in clear plastic like a cheap sofa.
Thank you both anyway
If you or someone you know has reviewed or been awarded a Human Frontier Science Program (HFSP) Program grant, can you contact me? Thanks in advance.
A good core won't need or use bsa in sheath fluid. Most don't. I was disabused of the need for bsa early on.
PMID: 30792265
Damn @lucasbsullivan.bsky.social you made the first version of a starter pack? Im jellyyyy
This is what studying O-GlcNAc feels like, w/ @lucasbsullivan.bsky.social #glycotime
SP3/PAC beads or
3kDa MWCO filters or
Protein precipitation or
Desalting columns or
Use less biotin and wash the cells more
A druggable redox switch on SHP1 controls macrophage inflammation www.biorxiv.org/content/10.64898/2026.02...
New preprint!
TL;DR: Network analysis reveals that CEBP/β and PU.1 stabilize regulatory architecture in tissue-resident alveolar macrophages to constrain inflammatory responses
www.biorxiv.org/content/10.6...
To turn spatial data into a 3D object, check our protocol (open source, napari plug-in). @guignardlab.bsky.social @adrianobolondi.bsky.social @ibdm.bsky.social
For example, if you have spatial RNA-seq as sections, you can align them automatically to analyse directly in 3D.
bio-protocol.org/e5607
I’m recruiting new members to the Farrell Lab this summer. We will have space for 1 postdoc (since Abhinav is leaving to start his own lab at U Arizona!!) and 2 postbacs, since my current two will leave for PhD programs at the end of the summer. More details in thread:
Wait til you see Southern California driving.
Please 🔁
My group at UBC received an allocation from the school to apply for the Canada Impact+ Training Awards (postdoc). Everything is moving fast but please email me in 48 hours with a CV if you are outside Canada and interested😎
Yachie lab: yachie-lab.org
sshrc-crsh.canada.ca/en/funding/o...
Has anyone tried hiding text in grants and manuscripts that tell AI readers this is great work? Asking for a friend....
Yusssss
"Except it doesn't bend on it's own. It's because we pull it in the direction of justice." Obama.
You can't think out of the box if you don't think. For how i see it this is not an inherent problem of AI, which at the end it's just at tool (for now). It's rather a problem inherent to us, human beings (aka lazy bastards).
Come join next week @lji.org!
