🆕💥🟢LIPS RCT Protocol: LInezolid Plus Standard of care
12 Swiss hospitals
Linezolid in addition to standard antibiotic treatment for Staphylococcus aureus bacteraemia
More combo /SA Bactremia
Clinda failed in SNAP,will LZD make it?
More combo from SNAP #idsky
bmjopen.bmj.com/content/16/4...

The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study Independent acquisition of plasmids and homoplastic mutations conferring antimicrobial resistance have occurred repeatedly in multiple lineages of S Typhi, predominantly arising in south Asia before s...

The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study - The Lancet Microbe www.thelancet.com/journals/lan...

Ionizing Radiation Changes the Electronic Properties of Melanin and Enhances the Growth of Melanized Fungi BackgroundMelanin pigments are ubiquitous in nature. Melanized microorganisms are often the dominating species in certain extreme environments, such as soils contaminated with radionuclides, suggestin...

Checkout this article I found at PLOS: dx.plos.org/10.1371/jour...

Genomic and physiological signatures of adaptation in pathogenic fungi - Nature Communications Emerging fungal pathogens have detrimental impacts on crops, animals, and humans, however little is known about their transition to a pathogenic lifestyle. This study demonstrates that the transition ...

Genomic and physiological signatures of adaptation in pathogenic fungi doi.org/10.1038/s414...

Synergistic interactions between Candida albicans and Enterococcus faecalis promote toxin-dependent host cell damage | PNAS The fungus Candida albicans and the Gram-positive bacterium Enterococcus faecalis share mucosal niches in the human body. As opportunistic pathogen...

Enterococcal cytolysin, add to pathogenicity: Synergistic interactions between Candida albicans and Enterococcus faecalis promote toxin-dependent host cell damage | PNAS share.google/fiK7cIw373xC...

Fecal microbiota transplantation plus pembrolizumab and axitinib in metastatic renal cell carcinoma: the randomized phase 2 TACITO trial Nature Medicine - In a double-blind, placebo-controlled phase 2 trial in patients with metastatic renal cell carcinoma treated with anti-PD-1 plus a VEGFR tyrosine kinase inhibitor, donor fecal...

An interesting role for faecal transplants rdcu.be/e1JKV

Bradyzoite subtypes rule the crossroads of Toxoplasma development rdcu.be/e1zCI

This online course presents the current knowledge on PK/PD of common antibiotics & antivirals, setting clinical breakpoints, individualised dosing & TDM. Innovative approaches for drug development also highlighted.

More: https://ow.ly/mszr50XXS9H

⏰Register by 09 March 2026!

#IDSky #clinmicro

Antibiotic Therapy for Uncomplicated Acute Appendicitis This observational follow-up of patients in the Appendicitis Acuta multicenter randomized clinical trial conducted in Finland assesses the 10-year appendicitis recurrence and appendectomy rate in adul...

Antibiotic Therapy for Uncomplicated Acute Appendicitis: jamanetwork.com/journals/jam...

ESPAUR Abstracts Published: Perspectives on a valuable resource for tackling antimicrobial resistance | UK Health Security Agency UKHSA's English Surveillance Programme for Antimicrobial Utilisation and Resistance (ESPAUR) abstracts are now available in a dedicated journal supplement, making this vital data more accessible to re...

www.linkedin.com/posts/uk-hea...

Albumin orchestrates a natural host defence mechanism against mucormycosis - Nature Albumin selectively inhibits Mucorales growth through the release of bound free fatty acids.

Albumin orchestrates a natural host defence mechanism against mucormycosis | Nature share.google/gKuxL49O8Fsj...

The hidden link between cefiderocol resistance and increased virulence in Klebsiella pneumoniae: Insights from a TraDIS-based investigation The emergence of extensively drug-resistant Enterobacterales, particularly carbapenemase-producing Klebsiella pneumoniae, poses a serious global health threat. Cefiderocol (FDC), a sideromycin antibio...

The hidden link between cefiderocol resistance and increased virulence in Klebsiella pneumoniae: Insights from a TraDIS-based investigation - Clinical Microbiology and Infection www.clinicalmicrobiologyandinfection.org/article/S119...

My Top Songs of 2025 Spotify

The songs I listened to most this year. #SpotifyWrapped
www.spotify.com/wrapped-shar...

My Top Song of 2025 Spotify

Disenchanted took my top spot this year. More in my #SpotifyWrapped
www.spotify.com/wrapped-shar...

Impact of an antimicrobial stewardship bundle on the outcome of high-risk neutropenic patients with fever: a pre-post study AbstractBackground. Rapid antibiotic initiation is essential for managing potential infections following chemotherapy-induced neutropenia. However, excessi

In high-risk febrile neutropenic patients, an AMS bundle safely reduced broad-spectrum antibiotic use, shifting from MEM to CAZ and shortening treatment duration
A meaningful step forward in #AntimicrobialStewardship in high-risk populations
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

Aztreonam-Avibactam: A Review in the Treatment of Serious Bacterial Infections Caused by Aerobic Gram-Negative Organisms - Drugs Aztreonam-avibactam (Emblaveo™), a fixed-dose combination of the monobactam antibacterial agent aztreonam and the broad-spectrum β-lactamase inhibitor avibactam, has been developed as a treatment, adm...

The key question is, where does Emblaveo fit when chosing empirical therapy?link.springer.com/article/10.1007/s40265-0...

Stewardship 2.0: Harnessing Data, Tech, and Teamwork to Save Antibiotics When we think about the rise of antibiotic-resistant superbugs, our minds typically go to one place: the unwell patient. The prevailing wisdom is that antimicrobial resistance (AMR) is a direct conseq...

My thoughts on AMS and where we are heading: www.linkedin.com/pulse/stewar...

Resolving a neonatal intensive care unit outbreak of meticillin-resistant Staphylococcus aureus to the single-nucleotide variant level using Oxford Nanopore simplex reads and HERRO error correction Our laboratory began prospective genomic surveillance for healthcare-associated organisms in 2022 using Oxford Nanopore Technologies (ONT) as a standalone platform. While effective for early outbreak ...

Resolving a NICU outbreak of meticillin-resistant Staphylococcus aureus to the single-nucleotide variant level using Oxford Nanopore simplex reads and HERRO error correction www.journalofhospitalinfection.com/article/S019... @alanmcn1.bsky.social @wvschaik.bsky.social @jessicamablair.bsky.social

Advancements in urinary tract infections: understanding, prevention, diagnosis, and treatment - Bhaskar K. Somani, 2025

Advancements in urinary tract infections: understanding, prevention, diagnosis, and treatment doi.org/10.1177/2049...

Empiric antibiotics for moderate-severe community-Acquired Pneumonia: We ought to serve patients better! - More studies needed www.clinicalmicrobiologyandinfection.org/article/S119...

Read this properly now and it really is a staggeringly beautiful study. And super important. Opens a new avenue of research I reckon. One of my papers of the year.

Cardiac Manifestations of Mycoplasma pneumoniae Infections: A Cohort Study 2007–2024 A 17-year cohort shows higher incidence of cardiac involvement than previously reported in patients admitted with Mycoplasma pneumoniae infections that may

Cardiac Manifestations of Mycoplasma pneumoniae Infections: A Cohort Study 2007–2024 url: academic.oup.com/cid/article/...

Teicoplanin total trough concentration and adverse effects in patients with hypoalbuminemia The association between Teicoplanin (TEIC) total trough concentration (Cmin) and adverse effects (hepatotoxicity, nephrotoxicity, and thrombocytopenia) in patients with hypoalbuminemia remains poorly ...

Teicoplanin total trough concentration and adverse effects in patients with hypoalbuminemia - Journal of Infection and Chemotherapy www.jiac-j.com/article/S134...

The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study Independent acquisition of plasmids and homoplastic mutations conferring antimicrobial resistance have occurred repeatedly in multiple lineages of S Typhi, predominantly arising in south Asia before s...

The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study - The Lancet Microbe www.thelancet.com/journals/lan...

Brief antibiotic use drives human gut bacteria towards low-cost resistance - Nature Brief ciprofloxacin exposure in humans drives antibiotic resistance evolution in gut bacteria through selective sweeps, particularly involving DNA gyrase mutations, which persist long after exposure a...

www.nature.com/articles/s41...

To tackle antibiotic resistance (#AMR) in newborns, especially premature babies in #NICUs, researchers explored the best trial design for studying #IPC.

See what this simulation study, based on #NeoIPC data and presented at #ESCMIDGlobal, suggests 👇

View poster: neoipc.org/wp-content/u...

#ESCMID2025 look up the code!!!

Using R coding #ESCMID2025

Using R! #ESCMID2025