Our latest work on shape-programmable tissues is out in @science.org. By positioning topological defects in cellular nematics, we encode frustrated 2D force fields that relax into predictable 3D shapes. Collaboration with Marino Arroyo’s lab, led by @pauguillamat.bsky.social at @ibecbarcelona.eu.
Posts by Artur
We had covered the history of traction force microscopy (TFM) earlier:
bsky.app/profile/epim...
But what about applying TFM into more physiologically relevant systems, such as those in 3D?
I am @barrasa-fano.bsky.social and I'll be your guide through this thread on #3DTractionForceMicroscopy.
I'm happy to present our new tool, EpiCure, a napari plugin to ease correction of segmentation and tracking of epithelia movies, developed in @devstempasteur.bsky.social
napari 0.7.0 is available now! 🚀🎉
It's a BIG release so read the full release notes, with highlights: napari.org/stable/relea...
We want to thank everyone who has worked incredibly hard on this release including our 11 new brilliant contributors 🤩 and the community for their support and feedback!
Faure, L. M., Gómez‐González, M., Baguer, O., Comelles, J., ... & Roca‐Cusachs, P. (2024). 3D Micropatterned Traction Force Microscopy: A Technique to Control 3D Cell Shape While Measuring Cell‐Substrate Force Transmission. Advanced Science, 11(46), 2406932. #EpithelialMechanics
buff.ly/Mpt1o3g
Now published in @natcomms.nature.com! 🥳
👉 rdcu.be/eATn3
We developed image analysis tools to capture the nematic orientation field of 3D tissue surfaces. Tested on epithelial aggregates, zebrafish hearts, myoblasts on spheres & micro-vessels, we combined soft matter physics with exp. biology.
Powered by @napari.org. Shout-outs to the steering council for letting me use the napari screenshot in the paper, and to @jni.codes for the quick back-and-forth on it!
First paper as first & corresponding author, out in PLOS Computational Biology! 🎉
napariTFM brings traction force & monolayer stress microscopy into napari, accessible via GUI; open-source, validated and no coding required. 😉
Check it out 👇
Background of DNA strand with logos of King's College London and the Leverhulme Trust and text 4 March 2026 Mechanosensing of epithelial cells: curvature, confinement and memory Professor Sylvain Gabriele University of Mons Force Talks Mechanics of Life Leverhulme DSP seminar series
Our next #ForceTalk is with Prof Sylvain Gabriele @sgabriele.bsky.social exploring "Mechanosensing of epithelial cells: curvature, confinement and memory"
📅 4 March 2026
🕒 15:00 - 16:00 GMT
Online & open to all 👉 www.kcl.ac.uk/events/force...
#mechanobiology @kingsnmes.bsky.social
Just a few days left for this application deadline!