Our NIAAA funded Post-DoctT32 has received its NoA (non competing renewal). Are you looking for a post-doc and interested in joining our amazing center? If so, reach out! Here is a convenient form that you can use to upload CV and a cover letter!
unc.az1.qualtrics.com/jfe/form/SV_...
We also find that local ancestry informed eQTLs better colocalize with GWAS signals from studies of common complex traits in these populations. Using expression data from mismatched populations (like GTEx) as well as methods that ignore local ancestry leads to poorer functional characterization.
We even find thousands of eQTLs with opposing effects on gene regulation depending on the ancestry of the haplotype they reside on. These variants are likely to be missed by GWAS in admixed pops because their effects would cancel out.
Ancestry underlying genes alters their genetic regulation in admixed populations. In Hispanic/Latinos and African Americans, ~50% of genes have >=1 eQTLs (~25% w/a causal eQTL) that differentially regulate expression given their underlying ancestry in our data. www.medrxiv.org/content/10.6...
Many living people carry fragments of Neanderthal DNA, remnants of ancient interbreeding events, with uneven distribution across chromosomes. New work by @sarahtishkoff.bsky.social lab suggests patterns are most consistent with Neanderthal contribution to human populations being highly male biased.🧪
Incredible! Congrats!
Don’t have plans for the evening of March 10? Then tune into Jeopardy! to watch yours truly compete :)
my local park is full of hundreds of snow sculptures and someone has been adding museum labels
🤯
Flyer with information about the Genetics & Neurobiology of Language summer course at Cold Spring Harbor, held on July 27th to August 3rd 2026, applications due by April 10th 2026. Instructors are Simon Fisher from the Max Planck Institute for Psycholinguistics, Netherlands, David Poeppel from New York University and Kate Watkins from the University of Oxford, UK. The course description is as follows: Why are children able to acquire highly sophisticated language abilities without needing to be taught? What are the neurobiological and neurophysiological processes that underpin human speech and language, and how do they go awry in developmental and acquired disorders? Which genetic factors contribute to this remarkable suite of human skills, and are there evolutionary precursors that we can study in other species? This unique CSHL course, in its sixth iteration, addresses these core questions about the bases and origins of speech and language, through talks, interactive sessions, keynotes and debates, involving leading experts from a range of disciplines. It integrates the state-of-the-art from complementary perspectives, including development, cognitive models, neural basis, gene identification, functional genomics, model systems and comparative/evolutionary studies. The invited speakers are: Jennifer Below, Vanderbilt University Elika Bergelson, Harvard University Esti Blanco-Elorrieta, New York University Jonathan Brennan, University of Michigan Karen Emmorey, San Diego State University Evelina Fedorenko, MIT Julia Fischer, Cognitive Ethology Laboratory, Germany Tecumseh Fitch, University of Vienna, Austria Adeen Flinker, NYU Langone Timothy Gentner, University of California, San Diego Liberty Hamilton, UC Berkeley Catherine Hobaiter, Wild Minds Lab, University of St. Andrews, UK Sonja Vernes, The University of St. Andrews, UK Sandra Waxman, Northwestern University For funding opportunities and additional course information, please go to: meetings.cshl.edu/courses
The course, now in its 6th iteration, covers key questions in speech & language research, with interdisciplinary perspectives spanning development, cognitive modeling, neural bases, gene identification, functional genomics, model systems & comparative/evolutionary studies. Applications due April 10.
Group photograph of faculty and participants of the very first Cold Spring Harbor summer course on Genetics and Neurobiology of Language in 2014, taken as the sun was going down at the Banbury Campus, Lloyd Harbor.
Please tell friends & colleagues about our unique course “Genetics & Neurobiology of Language” July 27-Aug 3 2026. Expert tutors, interactive talks, panel discussions, all in a beautiful setting. Scholarships available: meetings.cshl.edu/courses.aspx...
@cshlnews.bsky.social @cshlbanbury.bsky.social
6 members of my lab already expressed interest (and counting) ❤️🙋♀️
Fun news! @gcbias.bsky.social and I are teaching a 2-week online population genetics workshop this summer to raise money for the Center for Population Biology at UC Davis. We're trying to gauge interest -- please fill this out if you might be interested! And please share broadly!
This is incredibly powerful testimony.
Ms. Rahman is very tough and clear and was treated horribly.
Warning: I can't watch it without tears of rage.
www.youtube.com/watch?v=zrcW...
Pregnancy loss is common in humans, and chromosomal abnormalities are the leading cause. Using genetic data from ~140,000 IVF embryos, we show that maternal variation in meiosis genes influences recombination and aneuploidy risk.
First authors: @saracarioscia.bsky.social & @aabiddanda.github.io
Come work with us! Phenomenal opportunity to work with VUMCs recently whole genome sequenced biobank (300k patients) that is associated with extensive health record data.
apply.interfolio.com/177945
I was honored to speak up with my colleagues from across the government to demand Congress fight for the American people.
Happy to highlight an essay I wrote together with @marcdemanuel.bsky.social,
@natanaels.bsky.social and Anastasia Stolyarova, trying to think through what sets the mutation rate of a cell type in an animal species: www.biorxiv.org/content/10.6... 1/n
The name "Popular Science" doesn't mean we shift our coverage depending on public opinion. It means we cover relevant subjects that are rigorously researched, reliable, and grounded in reality.
And trans lives are grounded in reality.
We see y'all. No matter what.
www.popsci.com/science/tran...
Celebrating the retirement of my wonderful mentor and PhD advisor Doug Bishop @biz3000.bsky.social after more than 30 years at the University of Chicago studying homologous recombination! An incredible mentor to more than 50 grad students, postdocs, and other trainees
I rounded up some of the missing heritability discussions from the past few weeks and got the last word in (for now).
Excited to share our new FinnGen single-nucleus multiome preprint! 🧬
We profiled ~10M PBMCs (snRNA-seq + snATAC-seq) from 1,108 Finnish donors to map how genetic variants drive complex disease through chromatin and gene regulation 🧵👇
🔗 Link: www.medrxiv.org/content/10.1...
Great culture can save lives. Literally.
Amazing letter in today’s @thetimes.com about Tom Stoppard
TODAY IS THE DAY!
GET OUT AND VOTE. Polls are open 7 AM - 7 PM
WE GOT THIS!!!!!!
Are you looking for a collaborative international community of leaders in genetics, epidemiology, statistics, biology, and related biomedical disciplines? Then it's a great time to join IGES!
Sign up by January 31 using the code 2026EarlyRate to unlock full membership benefits at our lowest price.
How and for whom can genetics education reduce beliefs in genetic essentialism? pubmed.ncbi.nlm.nih.gov/41267401/
"We also find that the 3 intervention curricula are highly effective across sociodemographic group characteristics [...] we offer evidence-based strategies for curriculum development"
🧬 🦠 🏙️
Urban vs rural lifestyles create dramatically different gut microbiomes. But how do these different gut microbiomes affect the host?
Excited to share our new paper: www.biorxiv.org/content/10.1...
We are reading it right now too! My children have been demonstrating what it would be like if their pillows were actually made of marshmallow.
