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Posts by George Sflomos

Video

How can researchers and patient advocates actually work together — and what does meaningful collaboration look like in practice?

Episode 31 of The Cancer Researcher Podcast tackles this topic head-on.

Listen now: magazine.eacr.org/an-open-foru... 🎧

1 week ago 3 1 0 0
PI3K Inhibition in Combination with Tamoxifen in Patients with Metastatic HR+/HER2− Breast Cancer: Clinical and Circulating Tumor DNA Results AbstractPurpose:. To determine the safety and efficacy of taselisib, a selective PI3K inhibitor, in combination with tamoxifen.Patients and Methods:. POSEIDON is a phase II, randomized, placebo-contro...

PI3K Inhibition in Combination with Tamoxifen in Patients with Metastatic HR+/HER2− Breast Cancer!
This started with the RATHER project, which was part of the EU's FP VII funded (cordis.europa.eu/project/id/2...)
@caldaslab.bsky.social always walked the walk!

aacrjournals.org/clincancerre...

1 week ago 4 3 1 0
We’re the UK’s leading breast cancer charity

We’re the UK’s leading breast cancer charity

We’re combining the power of science and support to change breast cancer. Now.

We’re combining the power of science and support to change breast cancer. Now.

We’re funding world-class science now, so no one died of breast cancer in the future.

We’re funding world-class science now, so no one died of breast cancer in the future.

We’re here with life-changing support now, so no one has to face breast cancer alone.

We’re here with life-changing support now, so no one has to face breast cancer alone.

We're researching relentlessly now. For a future where no one dies of breast cancer. 🔬

We're here with support now. Until the day you no longer need us.​ ❤️

We're demanding change now. So everyone can get the best treatment. 📢

4 weeks ago 9 4 1 2
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Patrick Aouad: Major Preclinical Models Used to Study Breast Cancer Metastasis - OncoDaily Patrick Aouad: Major Preclinical Models Used to Study Breast Cancer Metastasis / Berthe Hayar, cancer, Cathrin Brisken, Ciara Metcalfe, George Sflomos, Karim

Terrific study! This review will be a super useful tool to people working with preclinical models!

oncodaily.com/voices/patri...

4 weeks ago 2 1 0 0
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Introduction | Cancer Genomics, Multiomics and Computational Biology | The European Association for Cancer Research Key dates

You have until 16 March to apply for travel grants and submit abstracts for Cancer Genomics, Multiomics and Computational Biology!

This extremely popular EACR conference showcases the latest breakthroughs in this exciting field with a cutting-edge programme.

1 month ago 2 4 0 2
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Who should attend our FREE public webinar with the @CGIclinics project?

👉️ Clinical molecular biologists & pathologists
👉️ Oncologists in precision medicine & phase I clinical trials
👉️ Researchers in precision oncology & cancer genomics
👉️ Bioinformaticians in clinical oncology labs

buff.ly/KQL1KDS

1 month ago 1 4 0 0

Super useful tool to people working with preclinical models!

Terrific work @patrickaouad.bsky.social summarising decades of research to provide a review on the major preclinical models used to study breast cancer metastasis.

1 month ago 0 0 0 0
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Sign up by 6 March for the EMBO Lab Leadership #training "How to write a scientific paper" delivered by EMBO Press editors at EMBO | EMBL Symposium "#AI and #biology." 🧪 www.embl.org/about/info/course-and-co... #EESAIBio #EMBOevents

1 month ago 6 4 0 1
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EACR 2026 Congress: Innovative Cancer Science | EACR2026

Have you submitted your abstract yet for #EACR2026 Congress (Budapest, 8-11 June)?

Don't miss the exciting opportunity to showcase your research and build new connections and collaborations with the global cancer research community.

You have until 04 March to get your submissions in: 2026.eacr.org

2 months ago 2 6 0 0
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Cancer Researchers to Watch - An Early Career Showcase | EACR2026 The Early Career Showcase in Budapest at EACR 2026, taking place on 07-08 June, will bring together the next generation of cancer researchers for two days of scientific exchange and community building....

Are you an early career researcher attending #EACR2026 in Budapest this June?

You may be eligible to attend our FREE early career showcase, Cancer Researchers to Watch, taking place 7-8 June!

Learn more:

1 month ago 2 2 0 0
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All- don't miss the chance to register for the European Association for Cancer Research meeting in Budapest in June.

I'll be there if you want to chat about all things microproteins!

#EACR
#CancerResearch

2 months ago 5 2 0 0
Introduction | Career Masterclass for Early Career Cancer Researchers | The European Association for Cancer Research

EACR Career Masterclass 2026 website is now live!
An exceptional virtual programme for early-career cancer researchers with practical career insights.
🗓 17–18 November 2026 | 🌍 Online eacr.org/conference/c...
#EACR #CancerResearch #EarlyCareerResearchers

3 months ago 1 1 0 0
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Got some down time before the New Year? Catch up with The Cancer Researcher Podcast, where we dive into the inspiring and challenging world of being a cancer researcher.

Explore topics from navigating imposter syndrome to mastering scientific communication: magazine.eacr.org/podcast/

3 months ago 6 4 0 1
Video

Registration is now OPEN for the cancer research community to join us for the #EACR2026 Congress! 🥳

Don't miss the opportunity to take advantage of our discounted early registration rate to attend, available until 21 April.

2026.eacr.org

3 months ago 3 6 0 0

I was pleased to contribute as a speaker to the first European Association for Cancer Research (EACR) – Organisation of European Cancer Institutes (OECI) virtual event on Patient Involvement in Cancer Research.

3 months ago 1 0 0 0

Check this out👇
Our neighbors @pietraslab.bsky.social has just published a new preprint detailing high-resolution profiling of the irradiated GBM microenvironment. ❄️Cool reading for the holidays❄️ Thanks for including us!

3 months ago 7 2 0 0
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Whole-genome landscapes of 1,364 breast cancers - Nature Whole-genome and transcriptome analysis of 1,364 cases of breast cancer from South Korea broadens our understanding of breast cancer biology and reveals genomic features that connect tumour biology with treatment responses and clinical outcomes.

Nature research paper: Whole-genome landscapes of 1,364 breast cancers
go.nature.com/48PM7Or

4 months ago 18 5 1 0
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Registration for our next edition of Liquid Biopsies is now open 🎉

Join world-leading experts and emerging investigators to explore the latest advances in circulating nucleic acids, circulating tumour cells & extracellular vesicles across the cancer continuum.

eacr.org/conference/l...

5 months ago 3 2 0 0
Video

You have until 15 December to register for our upcoming virtual conference! We will explore a seemingly paradoxical approach to cancer therapy, based on the deliberate hyper-activation of cancer-relevant signalling pathways.

Register from €60: eacr.org/conference/o...

5 months ago 5 3 0 1
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There's no better day than #WorldCancerResearchDay to register for our next virtual conference, Patient Involvement in Cancer Research! Learn how to make your research better and more impactful. Registration closes on Monday.

Learn more: eacr.org/conference/p...

6 months ago 4 2 0 0
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EACR members! Join us for an interactive workshop on scientific publishing, where expert scientific editors will guide you through the essential steps of getting your research into the academic spotlight.

📅 29 September, 14:00-15:30 CEST
🌍 Zoom

us02web.zoom.us/meeting/regi...

7 months ago 3 4 0 0
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Stand out in your career & boost your research impact 💥

Funders & journals now expect real patient involvement. Join this event to get practical insights to collaborate better & future-proof your research.

Registration closes 29 Sept - don’t miss it! 👉 eacr.org/conference/p...

7 months ago 2 3 0 0
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Constructive Critics: Development's approach to peer review We're all familiar with complaints about peer review. Some think it's biased – editors (especially from ‘those’ journals) seem to have too much power to decide what gets published. It can be opaque – ...

New @dev-journal.bsky.social editorial

We know we have high standards - but we're committed to making publishing with us constructive

From clear revision guidance to limitations sections & transparent peer review, we're here to help you share your science

journals.biologists.com/dev/article/...

1 year ago 115 46 3 7
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Why scientists are flocking to Substack A new generation of researchers is using the platform to build audiences and monetize their knowledge.

Nature Careers reports on how a new generation of researchers are using Substack as a way to build audiences and monetize their knowledge. #Academicsky 🧪

7 months ago 8 6 0 0
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Join us this November in Bergamo to help shape the future of early-onset cancer research!

We're excited to bring you this brand new conference topic, exploring the biology, causes and detection of cancer in younger patients.

In partnership with @themarkfdn.bsky.social 💙

eacr.org/conference/m...

1 year ago 13 9 0 2
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Structural mechanism of H3K27 demethylation and crosstalk with heterochromatin markers Chien-Chu Lin et al. reveal the structure of the histone demethylase KDM6B bound to the nucleosome. The study shows how KDM6B is positioned for H3K27 demethylation and how heterochromatin features suc...

Structural mechanism of H3K27 demethylation and crosstalk with heterochromatin markers

www.cell.com/molecular-ce...

8 months ago 1 1 0 0

We used ~normal human mammary epithelial cells (HMECs) to test CDH1 loss (modeling ILC) vs inhibiting E-cadherin, i.e. genetic suppression vs signaling block, to define how CDH1 loss is fundamentally different that 'simply' losing E-cadh mediated cell contacts. I.e. is this ~EMT, or not? 2/n

9 months ago 2 1 1 0

As we learn more re CDH1 loss-induced lineage reprogramming, we can develop new risk assessment strategies for benign ILC precursors, build prevention strategies, and target "truncal" effects of CDH1 loss in overt ILC to target the changes that likely are important in every single cancer cell. 5/5

9 months ago 4 1 0 0

So CDH1 loss causes a lineage remodeling in normal HMEC, locking cells in a new luminal progenitor-like state. This may explain why nearly all ILC are luminal-type (i.e. ER+) and point to CDH1 loss as a critical "bottleneck" in breast oncogenesis specific to ILC. 4/n

9 months ago 5 1 1 0

We did a thing w @jostrander.bsky.social!
Over the last few years, we took a new direction into #lobular breast cancer oncogenesis. We know loss of the gene CDH1 (E-cadherin) is central to ILC, and is among its earliest oncogenic events. But why? How does this push normal breast toward cancer? 1/n

9 months ago 10 4 1 1