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Posts by John Doench

Pete Hegseth Replaces Top General With Horse That Drinks Beer

Pete Hegseth Replaces Top General With Horse That Drinks Beer

Pete Hegseth Replaces Top General With Horse That Drinks Beer theonion.com/pete-hegseth-replaces-to...

2 weeks ago 5136 844 111 81
actual nytimes headline 

FEMA Official Says He Teleported to Waffle House. Experts Are Dubious.

actual nytimes headline FEMA Official Says He Teleported to Waffle House. Experts Are Dubious.

you, a naive fool: i do believe there are some things the nytimes won’t both sides

the nytimes:

2 weeks ago 13616 3140 138 530
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looking good Mr President

3 weeks ago 1226 254 14 8
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Susie Wiles, Trump’s White House Chief of Staff, Has Breast Cancer

Breast cancer mortality dropped 58% from 1975 to 2019.

Localized, early detected breast cancer has a 99% 5 year survival rate.

Modern mammogram tech was developed by NASA for telescopes.

Last year, RFK Jr. cancelled 87 research grants on breast cancer.

www.nytimes.com/2026/03/16/u...

1 month ago 5677 2572 239 118
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Nitrogen, Ammonia, and the Strait of Hormuz

I mean, these are always good. But this is So Good.

Nitrogen, Ammonia, and the Strait of Hormuz | Science | AAAS www.science.org/content/blog...

1 month ago 3 2 1 0

They made them take down the videos because they would cause "reputational damage" to people like this young man, Nathan Cavanuagh, so definitely don't post this all over the internet with the name Nathan Cavanaugh attached, or this guy might suffer reputational damage. This guy, Nathan Cavanaugh.

1 month ago 8833 4761 341 253
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Holy shit. These people shouldn’t be near sharp cutlery, let alone seats of power.

Mullin: “This is war.”

Raju: “You concede this is war?”

Mullin: “We haven’t declared war.”

Reporter: “You just said it’s a war.”

Mullin: *stammer

1 month ago 2920 816 167 218
Lowly Worm applecar

Lowly Worm applecar

I’ve been to Busytown. I’ve seen these things in action.

2 months ago 24 3 0 0
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Incredible. We got to "Is a pedophile island really all that bad?" five times faster than I thought.

2 months ago 7906 1694 283 40
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On the unintentional comedy scale, this was 10 of 10 for me.

2 months ago 16 4 4 0
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This style of post is literally every second thing I see on here and it’s utterly absurd. Van Hollen in particular could not be a worse target.

2 months ago 625 81 29 19

Gonna be a while until I can bike to work again... grr...

2 months ago 2 0 1 0
He has made Judges dependent on his Will alone, for the tenure of their offices, and the amount and payment of their salaries.

He has erected a multitude of New Offices, and sent hither swarms of Officers to harrass our people, and eat out their substance.

He has kept among us, in times of peace, Standing Armies without the Consent of our legislatures.

He has affected to render the Military independent of and superior to the Civil power.

He has combined with others to subject us to a jurisdiction foreign to our constitution, and unacknowledged by our laws; giving his Assent to their Acts of pretended Legislation:

For Quartering large bodies of armed troops among us:

For protecting them, by a mock Trial, from punishment for any Murders which they should commit on the Inhabitants of these States:

For cutting off our Trade with all parts of the world:

For imposing Taxes on us without our Consent:

For depriving us in many cases, of the benefits of Trial by Jury:

For transporting us beyond Seas to be tried for pretended offences:

For abolishing the free System of English Laws in a neighbouring Province, establishing therein an Arbitrary government, and enlarging its Boundaries so as to render it at once an example and fit instrument for introducing the same absolute rule into these Colonies:

For taking away our Charters, abolishing our most valuable Laws, and altering fundamentally the Forms of our Governments:

For suspending our own Legislatures, and declaring themselves invested with power to legislate for us in all cases whatsoever.

He has abdicated Government here, by declaring us out of his Protection and waging War against us.

He has plundered our seas, ravaged our Coasts, burnt our towns, and destroyed the lives of our people.

He has made Judges dependent on his Will alone, for the tenure of their offices, and the amount and payment of their salaries. He has erected a multitude of New Offices, and sent hither swarms of Officers to harrass our people, and eat out their substance. He has kept among us, in times of peace, Standing Armies without the Consent of our legislatures. He has affected to render the Military independent of and superior to the Civil power. He has combined with others to subject us to a jurisdiction foreign to our constitution, and unacknowledged by our laws; giving his Assent to their Acts of pretended Legislation: For Quartering large bodies of armed troops among us: For protecting them, by a mock Trial, from punishment for any Murders which they should commit on the Inhabitants of these States: For cutting off our Trade with all parts of the world: For imposing Taxes on us without our Consent: For depriving us in many cases, of the benefits of Trial by Jury: For transporting us beyond Seas to be tried for pretended offences: For abolishing the free System of English Laws in a neighbouring Province, establishing therein an Arbitrary government, and enlarging its Boundaries so as to render it at once an example and fit instrument for introducing the same absolute rule into these Colonies: For taking away our Charters, abolishing our most valuable Laws, and altering fundamentally the Forms of our Governments: For suspending our own Legislatures, and declaring themselves invested with power to legislate for us in all cases whatsoever. He has abdicated Government here, by declaring us out of his Protection and waging War against us. He has plundered our seas, ravaged our Coasts, burnt our towns, and destroyed the lives of our people.

He really is doing all of it.

3 months ago 6470 1981 150 119
Screenshot of a tweet from @MichaelCarusi
The three stages of career development: 
1. I can't wait until I'm important enough to be included in meetings. 
2. I feel so important being in these meetings! 
3. I will do anything legal and several illegal things to avoid these meetings.

Screenshot of a tweet from @MichaelCarusi The three stages of career development: 1. I can't wait until I'm important enough to be included in meetings. 2. I feel so important being in these meetings! 3. I will do anything legal and several illegal things to avoid these meetings.

Nothing prepares you for how rapidly you accelerate between these three states #chemchat

3 months ago 153 27 4 5
It's one of those white cutouts that people put up in their yards that is supposed to show Joseph and Mary praying over a baby Jesus with a round halo above his head, and a star just behind the structure.

It's one of those white cutouts that people put up in their yards that is supposed to show Joseph and Mary praying over a baby Jesus with a round halo above his head, and a star just behind the structure.

Mary and Joseph praying over Jesus in the manger, or
TWO T. REXES FIGHTING OVER A TABLE SAW?

Once seen, cannot be unseen.

3 months ago 415 123 15 9
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Drs. Matthew Meyerson and Heidi Greulich from the @broadinstitute.org sit down and discuss how they and Bayer scientists developed the first FDA-approved #CancerDrug to come from a Broad scientific discovery.

🤝 Learn more about their academic-industry alliance: https://bit.ly/4ruQNRl

4 months ago 4 2 0 0

Magnolia's Cafe on Rochester's deep blue Park Ave might seem like a strange place to meet Trump supporters. But over the clank of metal spoons against bowls of tomato soup, you can hear whispers that the president's friendly meeting with Mamdani may be the beginning of a pivot to the center.

4 months ago 298 17 10 4
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blog.addgene.org A Tour of Addgene's Most Popular Pooled Libraries

Thank the @johndoench.bsky.social and Root labs for depositing these deliciously named libraries, and check out our blog post for more:

5 months ago 9 2 0 0
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FPbase Fluorescence Spectra Viewer An interactive fluorescence spectra viewer to evaluate the spectral properties of fluorescent proteins, organic dyes, filters, and detectors.

The FPbase spectra viewer just had it's biggest software refactor in 6 years. It *should* be largely invisible to the end user (hopefully just faster and less buggy). Please let me know if you find any issues as you use it!

www.fpbase.org/spectra/

5 months ago 113 36 5 2

First 🟦 post - my main postdoc work is out in the world! We designed a Cas12a-based genetic screen to identify host factors that contribute to infection by the tickborne pathogen Rickettsia parkeri, and stumbled across a really exciting direct interaction between host and bacterium🦠. Check it out!

5 months ago 14 5 1 0
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Nature suggests you use their "Manuscript Adviser" bot to get advice before submitting

I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:

5 months ago 871 252 35 28
ICE Agent, 7-Year-Old Both Wearing Same ‘Military Commando’ Halloween Costume

ICE Agent, 7-Year-Old Both Wearing Same ‘Military Commando’ Halloween Costume

ICE Agent, 7-Year-Old Both Wearing Same ‘Military Commando’ Halloween Costume

5 months ago 12480 2724 312 150

When I explain that boycotting an election over an issue has never once forced a politician to embrace that issue, I'm not "scolding people to vote." I'm explaining reality.

Feel free to sit on your ass! Just don't pretend that your lazy apathy is somehow going to advance your agenda.

5 months ago 6896 1290 292 104
An illustrated map of Jamaica Plain Open Streets on Centre Street from Lamartine St. to South St from 10:30 a.m. - 3 p.m.

An illustrated map of Jamaica Plain Open Streets on Centre Street from Lamartine St. to South St from 10:30 a.m. - 3 p.m.

Enjoy car-free small business shopping, music, games, bicycling, community tabling, and more in Jamaica Plain this weekend!

📍 : Centre Street from Lamartine St. to South St. in JP
⏰: This Sunday, November 2 from 10:30 a.m. to 3 p.m.

More info: boston.gov/open-streets

5 months ago 24 15 1 5
Vance Flexes the Marines’ Might as Thousand Protest Trump’s Agenda
VP JD Vance’s trips o a military base in California illustrated rising tensions between the federal government and Democratic leaders

Vance Flexes the Marines’ Might as Thousand Protest Trump’s Agenda VP JD Vance’s trips o a military base in California illustrated rising tensions between the federal government and Democratic leaders

This is quite a hed/subhed.
1) Start with Vance. Use strong action verb. Accept the autocratic premise that the “Marines’ Might” are Vance’s to flex.
2) Mention the protest second and absurdly describe them as in the thousands
3) Treat Trump’s strong man use of the military as a partisan scuffle.

6 months ago 3027 796 90 110

Remember, brown 13-year-olds are hardened menaces to society, but 30-something Republican Hitler afficionados in positions of power are just li’l guys.

6 months ago 3798 1100 14 15
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new at addgene

new at addgene

New CRISPR libraries from the @johndoench.bsky.social and Root labs — Jacquere (human) and Julianna (mouse).
A perfect pairing for your next screen. 🍷🧀
https://twp.ai/9PX2kT
https://twp.ai/4irnYP

6 months ago 4 5 0 0

I have lived and worked in and around Chicago for 27 years and I have been assaulted less often than Sen Paul has been in his own back yard.

6 months ago 12156 2672 342 90
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79. American citizen.

6 months ago 23827 11657 1963 1352