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A TRPV4-dependent calcium signaling axis regulates lamellipodial actin architecture to promote cell migration Cell migration is crucial for development and tissue homeostasis, while its dysregulation leads to severe pathologies. Cell migration is driven by the…

Our paper on how calcium controls lamellipodial actin assembly is out in Current Biology! Huge congrats to Ernest Iu, Alex Bogatch, and all the authors - fantastic collaboration!

www.sciencedirect.com/science/arti...

2 months ago 6 3 0 0
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A real pleasure to host Martin Schwartz in Toronto as the external examiner for Fernando Valencia’s PhD defense. Congratulations, Dr. Valencia!

10 months ago 4 0 0 0
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A TRPV4–dependent calcium signaling axis governs lamellipodial actin architecture to promote cell migration Cell migration is crucial for development and tissue homeostasis, while its dysregulation leads to severe pathologies. Cell migration is driven by the extension of actin–based lamellipodia protrusions...

Excited to share our latest work on how Ca²⁺ regulates actin in cell protrusions—now available as a preprint on bioRxiv! 🎉 Huge congrats to Ernest Iu for leading the project, and a special thanks to our amazing collaborators!

www.biorxiv.org/content/10.1...

1 year ago 16 8 0 1