Data Management and Statistics Core Graduate Student Selected for Keystone Symposia - Cleveland Alzheimers Disease Research Center Graduate student Carly Rose to present CADRC Data Management and Statistics Core research on COVID-19, Shingrix, and Alzheimer’s disease risk at the 2026 Keystone Symposia in Germany.

Does the shingles vaccine impact Alzheimer’s risk?

CWRU’s Carly Rose presents new data at @KeystoneSymp showing COVID-19 may increase LOAD risk, while Shingrix offers protection.

clevelandadrc.org/carly-rose-k...

Case Western Reserve University awarded $6.2M to identify new targets to treat Alzheimer’s disease | CWRU Newsroom | Case Western Reserve University With a new $6.2 million, five-year grant from the National Institute on Aging, researchers at Case Western Reserve University will use artificial i...

Congratulations to Dr. Haines on his new grant award from the National Institute on Aging!

case.edu/news/case-we...

A New Era of Mentorship: Genesis Anderson and the HU-ERA-PREP Program Join the CADRC - Cleveland Alzheimers Disease Research Center University Hospitals becomes the first host site for Howard University’s HU‑ERA‑PREP program. Meet Genesis Anderson, B.A., our newest coordinator helping to advance Alzheimer’s research and cultivate ...

Exciting news! UH is the first host site for Howard University’s HU‑ERA‑PREP program. 🎓 Welcome to the CADRC team, Genesis Anderson! Together, we’re strengthening Alzheimer’s research and mentoring future investigators.

clevelandadrc.org/genesis-ande...

Reflecting on Progress: The 2026 CADRC External Advisory Committee Meeting - Cleveland Alzheimers Disease Research Center The CADRC hosted its 2026 External Advisory Committee meeting to review research progress and strategic goals for Alzheimer’s and related dementia research.

How does the CADRC stay at the cutting edge of dementia research? 🧠 Through rigorous review and national collaboration! We recently hosted our 2026 External Advisory Committee to refine our strategy for the year ahead.
#Alzheimers #Research #NIH

clevelandadrc.org/2026-cadrc-e...

CADRC Director Publishes New Insights into Early Behavioral and Cognitive Changes in Dementia - Cleveland Alzheimers Disease Research Center New CADRC research led by Dr. Jagan Pillai identifies three distinct clinical subtypes in early-stage dementia by analyzing combined cognitive and behavioral symptoms.

New CADRC study from Dr. Jagan Pillai and colleagues identifies 3 clinical subtypes in early dementia. Mapping these patterns helps improve diagnosis and personalized care.
#Dementia #Neuroscience #CADRC
#ClinicalResearch

clevelandadrc.org/pillai-early...

Is Alzheimer’s Transmissible? CADRC Experts Provide Clarity in New JAMA Neurology Editorial - Cleveland Alzheimers Disease Research Center A JAMA Neurology editorial by Dr. Brian Appleby and Dr. Mark Cohen evaluates claims of iatrogenic Alzheimer disease from historical growth hormone treatments, emphasizing that current medical practice...

Can Alzheimer’s pathology be transmitted? 🧠

A new @JAMANeuro editorial by Dr. Brian Appleby & Dr. Mark Cohen examines historical cases of iatrogenic amyloid-β.

Key takeaway: Modern medical care remains safe.

clevelandadrc.org/is-alzheimer...

New Insights on α-Synuclein Pathology and Clinical Phenotypes in Dementia With Lewy Bodies What drives faster decline in dementia with Lewy bodies? New studies uncover key pathological and clinical factors, offering insights for better prognosis and clinical trial design.

New research from CADRC Director, Dr. Jagan Pillai, shows the lines between DLB and Alzheimer’s are blurring. 🧠

By tracking early behavioral symptoms and biomarkers, researchers can now better predict disease progression and refine clinical trials.

consultqd.clevelandclinic.org/insights-on-...

Tech Update: CADRC Enhances Research with Digital Slide Scanner - Cleveland Alzheimers Disease Research Center The Cleveland Alzheimer’s Disease Research Center (CADRC) enhances its diagnostic capabilities with a new digital slide scanner. Learn how high-resolution digital imaging at the National Prion Disease...

Tech Update: The CADRC has purchased a new digital slide scanner. 🔬

Housed at the NPDPSC at CWRU, it converts glass slides into high-res digital images for better analysis and collaboration. This moves us closer to AI-driven pathology workflows.

#CADRC #CWRU #DigitalPathology

Celebrating Neuropathology’s Contributions to Alzheimer’s Disease Research Centers - Cleveland Alzheimers Disease Research Center Explore how neuropathology has served as the foundational "ground truth" for 40+ years of Alzheimer’s Disease Research Center (ADRC) discovery and how digital pathology is shaping the future of precis...

Celebrating 40+ years of ADRC excellence! 🧠 Our own Dr. Mark Cohen and Dr. Karin Mente have co-authored a new feature in Alzheimer’s & Dementia on the evolution of neuropathology clevelandadrc.org/neuropatholo...

#Neuropathology #ADRC #AlzheimersResearch #Neuroscience #PrecisionMedicine

Targeting Astrocyte Dysfunction: Dr. Benjamin L.L. Clayton Awarded Grant to Study Alexander Disease Mechanisms - Cleveland Alzheimers Disease Research Center Understanding the mystery of the astrocyte: CADRC REC scholar Dr. Benjamin L.L. Clayton investigates new therapeutic targets for the rare genetic Alexander Disease.

🔬 How do astrocyte mutations cause brain damage? CADRC REC scholar Dr. Benjamin Clayton is on the case.

With @CWRU & the End Alexander Disease Foundation, his lab is finding ways to restore gene activity and protect white matter in children. #RareDisease #Neuroscience #CADRC #AlexanderDisease

New NIA Grant Awarded to Dr. Tian Liu to Investigate Mitochondrial Links to Alzheimer’s Pathology - Cleveland Alzheimers Disease Research Center Could CHCHD10 be the key to stopping Alzheimer’s? CADRC REC alumni Dr. Tian Liu launches NIA-funded research into tau aggregates and mitochondrial health.

Congratulations to CADRC REC alumnus, who was awarded a two-year NIA Grant to investigate mitochondrial links to Alzheimer’s pathology.
#ENDALZ #alzheimers #brainhealth #CADRC

On the front lines of Alzheimer's outreach | CWRU Newsroom | Case Western Reserve University For students at Case Western Reserve University, some of the best lessons stem from some of their hardest moments. That much is true for Anuj Pullakan...

Fighting Alzheimer’s with Empathy and Science 🧠✨

CWRU students are turning personal loss into community gain. As Academic Ambassadors, they’re on the front lines of Alzheimer’s outreach—supporting families and driving life-changing research. #AlzheimersAwareness #CWRU #EndALZ #CaregiverSupport

Mapping the Brain: New Insights into Language-Based Alzheimer’s Your Content Goes Here Your Content Goes Here Mapping the Brain: New Insights into Language-Based Alzheimer’s When we think of Alzheimer’s disease, memory loss is often the first symptom that comes to mind. However, for a subset of patients, the journey begins differently—with subtle, yet persistent, challenges in language. This specific presentation, known as logopenic primary progressive aphasia (LPA), is the focus of a new study recently published in the Journal of Alzheimer’s Disease by researchers at the Cleveland Clinic and the Cleveland Alzheimer’s Disease Research Center (CADRC).

🧠 New research from the Cleveland Clinic and the Cleveland Alzheimer’s Disease Research Center shows that patients with logopenic primary progressive aphasia (LPA) exhibit distinct brain atrophy patterns on MRIs.

💡 Learn more about how researchers are mapping these unique brain changes on our…

Save Your Spot: Our Black History Month Brain Health Series Starts Next Week Your Content Goes Here Your Content Goes Here Save Your Spot: Our Black History Month Brain Health Series Starts Next Week Join the Cleveland Alzheimer’s Disease Research Center next Thursday, February 5th as we kickoff our 5th Annual Black History Month Webinar Series! On the agenda: Pollution, Toxins, and the Brain: The Hidden Threats in Our Communities Learn how toxins, including lead, air pollution, and emissions from industrial plants or waste sites can affect cognitive function.

Save Your Spot: Our Black History Month Brain Health Series Starts Next Week. Register here: bit.ly/BHMCADRC-2026

CADRC REC Scholar Awarded Grant to Study Mixed Dementia Biomarkers Your Content Goes Here Your Content Goes Here CADRC REC Scholar Awarded Grant to Study Mixed Dementia Biomarkers We are pleased to announce that CADRC REC Scholar, Carol Chan, MD, has been awarded a 3-year Clinician Scientist Research Development Grant from the Cleveland Clinic Neurological Institute. Dr. Chan serves as a geriatric psychiatrist at the Cleveland Clinic Center for Brain Health and is an Assistant Professor at the Cleveland Clinic Lerner College of Medicine.

CADRC REC Scholar Awarded Grant to Study Mixed Dementia Biomarkers

CADRC Newsletter | Mind Matters Issue 17 Your Content Goes Here Your Content Goes Here In Case You Missed It: CADRC Researchers Find that Alzheimer’s Disease Can Be Reversed in Animal Models A CADRC-led study challenges the belief that Alzheimer’s brain damage is permanent. Researchers restored cellular energy in animal models using a compound called P7C3-A20, which not only stopped disease progression but reversed existing brain damage and fully restored memory and cognitive function.

CADRC Newsletter | Mind Matters Issue 17

Your Content Goes Here Your Content Goes Here In Case You Missed It: CADRC Researchers Find that Alzheimer’s Disease Can Be Reversed in Animal Models A CADRC-led study challenges the belief that Alzheimer’s brain damage is permanent. Researchers restored…

Driving Toward a Cure: A Heartfelt Thanks to Our Partners - Cleveland Alzheimers Disease Research Center Your Content Goes Here

Revving with gratitude! 🏎️

CADRC’s fundraiser with Porsche Beachwood, NORPCA, and WD Detailing was a huge success! Donations support Alzheimer’s diagnostics and education.

Read more: clevelandadrc.org/driving-towa...

Round 2 is coming this Spring! 🌸

#Alzheimers #Cleveland #Porsche

Driving Toward a Cure: A Heartfelt Thanks to Our Partners Your Content Goes Here Your Content Goes Here Driving Toward a Cure: A Heartfelt Thanks to Our Partners The Cleveland Alzheimer’s Disease Research Center (CADRC) is revving with gratitude! On Saturday, January 16, we celebrated a highly successful fundraising event brought to life by a fantastic partnership: Porsche Beachwood, the Northern Ohio Region Porsche Club of America (NORPCA), and WD Detailing.

Driving Toward a Cure: A Heartfelt Thanks to Our Partners

Your Content Goes Here Your Content Goes Here Driving Toward a Cure: A Heartfelt Thanks to Our Partners The Cleveland Alzheimer’s Disease Research Center (CADRC) is revving with gratitude! On Saturday, January 16, we celebrated a highly…

We are excited to announce our 5th annual Black History Month Brain Health Webinar Series scheduled each Thursday in February. Don’t wait—secure your spot now to learn, connect, and access valuable resources for our community!
clevelandadrc.org/2025/12/19/c...
Register here: bit.ly/BHMCADRC-2026

Johns Hopkins Scientists Identify Key Brain Protein That May Slow Alzheimer’s Researchers have identified a brain protein whose absence leads to memory loss and Alzheimer’s-like damage in mice. Researchers at Johns Hopkins Medicine report that findings from a new study funded b...

Memory loss might be linked to the decline of a specific protein called CSE. Johns Hopkins researchers found that keeping this protein active could be the key to slowing Alzheimer's. Science moving us one step closer. 🧪✨ scitechdaily.com/johns-hopkin...

Dementia Patient and Caregiver Resources - Home - Brain Health Activities BHA is a series of programs designed to promote healthy brain aging in older adults. It is made by the University of Kentucky SBCoA.

Found a great resource! 🧠

The UK Sanders-Brown Center offers research-backed Brain Health Activity Guides for those with cognitive impairment and their caregivers.

Includes: 🎬 Videos 📝 Tip sheets 💡 Expert links

Check it out: dementiacaregiver.createuky.net/brain_health/

#BrainHealth #Caregiving

CADRC Researchers find that Alzheimer’s Disease Can Be Reversed in Animal Models For generations, the medical world has operated under a sobering assumption: once Alzheimer’s disease takes hold, the damage to the brain is permanent. Research has traditionally focused on building "roadblocks" to slow the disease down, rather than finding a way to turn the car around. However, a transformative new study led by Kalyani Chaubey, PhD, in the laboratory of CADRC co-Investigator…

Big news in Alzheimer’s research! A new study led by Kalyani Chaubey, PhD, in the lab of CADRC co-Investigator Dr. Andrew Pieper, is challenging 100 years of medical dogma. #AlzheimersResearch #BrainHealth #MedicalBreakthrough #Hope #CADRC #Neuroscience

Lewy Body Dementia - CADRC In LBD, clumps of a protein called alpha-synuclein collect in several areas of the brain, such as:

Did you know that there are two types of Lewy Body Dementia - Dementia with Lewy Bodies (DLB) and Parkinson’s Disease Dementia (PDD)? Both conditions are caused by the same problem: the buildup of Lewy bodies in the brain. Learn more on our website: clevelandadrc.org/education-re...

Can Cognitive Fluctuations Offer Insight Into Alzheimer’s Disease Neurobiology? Can moments of lucidity in Alzheimer’s reveal deeper insights into neurobiology? Our researchers are investigating cognitive fluctuations to improve diagnosis, monitoring and treatments. Learn about t...

Can cognitive fluctuations offer new insights into the neurobiology of Alzheimer’s disease?

A $4.9 million grant has been awarded to CADRC Director and collaborators at VA Puget Sound and UC San Diego to explore this vital question.

consultqd.clevelandclinic.org/cognitive-fl...

Lewy Body Dementia - CADRC In LBD, clumps of a protein called alpha-synuclein collect in several areas of the brain, such as:

Did you know that Lewy body dementia (LBD) is the 2nd most common progressive dementia after Alzheimer’s disease, with over 1.4 million Americans currently living with the disorder? Learn more about LBD on our website: clevelandadrc.org/education......

🧠 New Research Grant Awarded: “Decoding Alzheimer’s Disease Mechanisms via Integrated Multi-Omics and O-GlcNAc Profiling.” CADRC Clinical Core Leader, Dr. Brian Appleby, and collaborating researchers from NEOMED have been awareded $40k by the UH-NEOMED Brain Health Intramural Funding program for a new pilot research project titled "Decoding Alzheimer’s Disease Mechanisms via Integrated Multi-Omics and O-GlcNAc Profiling." The Team and The Project The project is led by Principal Investigators Dr. Priya Raman, PhD (NEOMED)

New research aims to uncover how metabolic dysfunction and vascular biology contribute to Alzheimer's Disease pathology and cognitive decline.

The CADRC Data Management and Statistics Core and Clinical Core teams met up for their annual In-Person meeting to help grow the ties of our team and prep for another year of great work! #alzheimersresearch #2026 #teamwork

Dr. Acosta Ingram awarded a new 3-year research grant from the Alzheimer’s Association! Please join us in congratulating Dr. Diana Acosta Ingram, a Post-Doctoral Fellow in the Kraus Lab at Case Western Reserve University! She was just awarded a new 3-year research grant from the Alzheimer’s Association. The project will study the importance of neuronal cholesterol transport in Alzheimer’s Disease. Dr. Acosta Ingram will use advanced human brain cell organoid models to test outcomes of the APOE4/E4 risk allele.

Please join us in congratulating Dr. Diana Acosta Ingram, a Post-Doctoral Fellow in the Kraus Lab at Case Western Reserve University! She was just awarded a new 3-year research grant from the Alzheimer’s Association.

Alzheimer's Disease Facts and Figures Read the 2025 report to understand the burden of Alzheimer's and dementia on individuals, caregivers, government and the nation's health care system.

www.alz.org/alzheimers-d...

Gift Guide for Caregivers and People Living with Dementia | alz.org The Alzheimer's Association holiday gift guide offers gift ideas for dementia caregivers and individuals living in the early, middle and late stages of Alzheimer’s.

Need gift ideas for loved ones in your life who are living with dementia or caring for someone with dementia? The Alzheimer's Association has your back. Visit www.alz.org/help-support...