Luis Larrondo @lflarrondo.bsky.social is illuminating 💡the role of light 🕯️ in the circadian clock ⏰

They are doing this by building 🏫 semi-synthetic clocks ⏰

#fungal26

Transcriptional rewiring of an evolutionarily conserved circadian clock | The EMBO Journal imageimageEukaryotic circadian oscillators share a one-step transcription-translation negative-feedback loop (TTFL) circuit design, where a main transcriptional complex drives expression of a negative element that can inhibit its own expression. ...

Luis on creating semi-synthetic oscillators (see their @embojournal.org paper: www.embopress.org/doi/full/10....) towards Minimal Synthetic Oscillators (MiSOs)

A new flavor of synthetic yeast communities sees the light | mBio The Earth is populated by a huge diversity of organisms, which rarely exist in isolation. Instead, they constantly interact with other biological agents shaping ecosystems and occupying distinct habit...

Luis describes their super synthetic biology tools for light controled mutualistic interactions (cross feeding) in fungi
=Optoecology

See their mBio:
journals.asm.org/doi/10.1128/...

Incredible Friday Seminar today from Luis Larrondo- fungal circadian clocks, and can fungi see? @johninnescentre.bsky.social @thesainsburylab.bsky.social #chronobiology

www.instagram.com/p/DOqZKWGgY7...

What a treat !! Last week we had the wonderful opportunity to enjoy an e-talk by @wcratcliff.bsky.social at our Faculty of Biological Sciences at the Universidad Catolica de Chile! Thanks a lot Will !

A symbiotic filamentous gut fungus ameliorates MASH via a secondary metabolite–CerS6–ceramide axis The gut microbiota is known to be associated with a variety of human metabolic diseases, including metabolic dysfunction–associated steatohepatitis (MASH). Fungi are increasingly recognized as importa...

#NatureMicroPicks

Friendly fungus!

A fungal isolation chip helped identify a human gut symbiotic fungus Fusarium foetens, which produces metabolites that alleviate fatty liver disease in mice. 🍄🐀

Published in @science.org

#MicroSky #MicrobiomeSky

www.science.org/doi/abs/10.1...

🚨 We're hiring! 🚨

Our lab is looking for a lab technician & a postdoc to study enzyme evolution across geologic time.

Learn more about one of our projects here: ⬇️
🔗 research.wisc.edu/uncategorize...

Folks who recently lost jobs are especially encouraged to apply! #Hiring #ScienceJobs

You rock!!! Keep that awesome science coming

also to Alfredo Herrera-Estrella (not in bsky yet :( )

Congratulations to all new fellows! In particular to @hittingerlab.bsky.social 🙌asm.org/Press-Releases/2025/Febr...