Example forelimb reaching movements of a mouse, and simultaneous recording of the membrane potential in the primary motor cortex.

▶️ In our new @plosbiology.org study with James Poulet, we show somatosensory contributions to M1 Vm in a forelimb reaching task.

▶️ Surgical removal of somatosensation impacted movement encoding, Vm regulation and its transition to active state, and more!

▶️ Learn more: doi.org/10.1371/jour...

🚨New book out on the "Challenges in #Navigation Research -Mapping New Directions" edited by @noranewcombe.bsky.social and Ken Cheng 🧭🗺🧠
It presents a multidisciplinary synthesis of research on animal navigation.
Check ot out, it is open access ↘️ doi.org/10.1007/978-... ↙️

Dorsoventral hippocampus neural assemblies reactivate during sleep following an aversive experience - Nature Neuroscience Synchronization of sharp-wave ripples across the dorsoventral hippocampus during sleep supports coordinated reactivation that represents negative experiences more faithfully than positive ones.

Our paper is out today!!! (not an April fool's day joke) Congrats to authors @azulsilva.bsky.social, @belalima-paiva.bsky.social, Ele Pronier, and mostly to the amazing scientist and human being who led this project @facuumm.bsky.social
#neuroskyence #hippocampus
www.nature.com/articles/s41...

Well done 👏 Nice to see it out !

My main postdoc work is now published: www.nature.com/articles/s41...! We (myself, Isabel Low, Frances Cho, and @lgiocomo.bsky.social) discovered task-relevant remote representations in entorhinal cortex independent of CA1. #paperthread below! 1/13

Ne nous inquiétons pas : le Crédit Impôt Recherche, subvention déguisée qui coûte à peu près deux fois le budget total du CNRS, continuera à faire briller la recherche française

This 1990 speech by Carl Sagan is timely times two:

#war #climate

I wish you all the best for this new adventure !

This rarely-seen Glass Octopus was caught on camera. The clear sea creature was filmed by an underwater robot during an expedition off of the Phoenix Islands more than 3,200 miles northeast of Sydney, Australia.

Original post

I don’t know but Darwin was complaining that his mind was less sensitive to music and art in his late days suspecting an atrophy of specific parts of the brain caused by this « machine »

Excited to co-organize a #COSYNE2026 workshop with Marieke Scholvinck (@zeronoiselab.bsky.social) on March 17 in Cascais 🧠🌊

*Inferring neural latent states from behavior*

Featuring fantastic speakers across experimental & computational #neuroscience (list below 👇)

Hope to see many of you there! 👋

It was nice to have you around and thanks for a great talk !

1/7 🧠 My journey into development begins with this work and question: how does the brain's spatial navigation system develop? We found that the neural networks for spatial navigation (tori and rings) are preconfigured and only later anchor gradually to the world with experience! 🧵

New paper hot off the (pre-)press! We dig into the evolutionary origins of neural computations for behavioral control across mice, monkeys, and humans: www.biorxiv.org/content/10.6....

As our lab's first foray into comparative analysis of neural dynamics, I’m super excited about this work! 1/18

A paid summer internship is available in Microsoft Research NYC for a *PhD student later in their degree*, with experience designing human questionnaires/experiments, collecting data on prolific, running statistical analysis, and writing papers. If you know exceptional candidates please ping me. 🙏

Now out in Hippocampus. Fei Wang‘s model of Trace Vector Cells and intra-subiculum processing, consistent with know effects in CA1.

onlinelibrary.wiley.com/share/CPZPYM...

Comparison of place field detection methods and their effect on place field stability and drift in mouse dCA1 for freely moving 1-photon imaging data

After 5 years of developing, a new preprint from the lab - introducing our workflow for comparative insect connectomics, aimed at democratizing connectomics. @erc.europa.eu @lundvision.bsky.social @biologylu.bsky.social Read it here: www.biorxiv.org/content/10.6...

Human hippocampal theta–gamma coupling coordinates sequential planning during navigation

Impressive study from Dan Bush's Lab at UCL:

www.pnas.org/doi/10.1073/...

Sleep spindles promote hippocampal network downregulation during sleep Sleep is thought to globally downregulate neuronal network activity and synaptic connections enhanced during prior wakefulness and, in parallel, to up…

Sleep spindles promote hippocampal network downregulation during sleep

www.sciencedirect.com/science/arti...

Vectorized instructive signals in cortical dendrites - Nature Mice learning a neurofeedback brain–computer interface task show neuron-specific teaching signals in cortical dendrites, consistent with a vectorized solution for credit assignment in the brain.

This paper on how the brain may do gradient descent is very cool: www.nature.com/articles/s41...

Always a pleasure to have you around ! Looking forward to the next time !

How do we balance external attention to the outside world and internal attention to our thoughts & memories?

We review evidence that external and internal attention can compete, unfold concurrently, or cooperate!

Loved working on this with @samversc.bsky.social & @tobiasegner.bsky.social!

New preprint out 🎉

What happens to the hippocampal “place code” when an animal is actively engaged in a task?

The answer surprised us (and might surprise you too!).

Let's dive in ⬇️

Link:
"Hippocampal trace coding dominates and disrupts place coding" www.biorxiv.org/content/10.6...

Place cells in CA1 lack topographical organization of firing locations | PNAS Topography is a well-described and well-known concept for cortical organization in primary sensory and motor cortices of mammalian brains. Similar ...

A half-century old question may have its final answer. Using high-resolution #Mini2P microscopes, we find no evidence of local topography in #PlaceCells. Place fields of neighbouring cells are no more similar than those of randomly selected cells. 🧠🗺️ Out now in @pnas.org www.pnas.org/doi/10.1073/...

Un événement à destination des patients, familles et associations de patients.

New preprint from the lab! Stefan Sun and @q-perrenoud.bsky.social collaborated to look at how sensory experience affects the adult cortex. Using ephys and 2-photon imaging, they found that varied visual experience reorganizes dendrite-targeting inhibitory circuits in V1.

👀👇