Exploring depression treatment response by using polygenic risk scoring across diverse populations Ancestrally diverse biobanks where medication, disease, and genetics are linked provide an opportunity to understand treatment response to major depressive disorder (MDD). We developed polygenic risk ...

📣New from @bpasaniuc.bsky.social & co
📄Exploring #depression treatment response by using #polygenic risk scoring across diverse populations

Interesting to see two new papers reporting variable accuracy of polygenic scores across non-genetic (or at least non-PRS) backgrounds.

Cudic et al considers intersections of age, sex, smoking, alcohol, income, and deprivation.

www.medrxiv.org/content/10.1...

Exciting work by the great @ruthiejohnson.bsky.social !! 👏

Postdoctoral Fellow in Statistical Genetics (f/m/x)

Dear statgen friends at #ASHG2023 #ASHG23, my lab is #hiring #phds #postdocs to work on heterogeneity and trajectories of psychiatric disorders using EHR/cohorts across US/Europe/Asia (incl. data from PGC), lots of cool stuff to be done!

Please reach out by email!
Ad link: tinyurl.com/7tae8k

NOT-MH-24-370: Notice of Information: NIMH List of Human Genes Having Rare Variants with Strong Statistical Support for Association to Mental Health Traits NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Information: NIMH List of Human Genes Having Rare Variants with Strong Statistical Support for Association t...

NIMH has a list of genes with strong statistical support for association with mental health phenotypes, and they are interested in supporting researchers want to investigate a particular gene

grants.nih.gov/grants/guide...