How does the brain build a memory?
A common assumption is that the neurons activated during an experience collectively form the memory engram.
In our new Nature Neuroscience paper (finally out!), we show that this is not the case.
www.nature.com/articles/s41...
fMRI connectivity is dominated by recurring high-amplitude BOLD events (CAPs, QPPs)
But what originates these events? Many think neuromodulation is the culprit. Our new work offers a simpler take: cortico-cortical dynamics alone can generate CAP-like events! doi.org/10.1371/journal.pcbi.1013995
🧵1/n
Our paper is out in @natneuro.nature.com!
www.nature.com/articles/s41...
We develop a geometric theory of how neural populations support generalization across many tasks.
@zuckermanbrain.bsky.social
@flatironinstitute.org
@kempnerinstitute.bsky.social
1/14
Terrific work led by @emmaroscow.bsky.social showing that hippocampal replay reflects events with large prediction errors, all the better to bootstrap learning as we slumber
Congratulations to Matt Jones & Nathan Lepora for seeing this through to the end!
www.nature.com/articles/s41...
Thanks @hunglo.bsky.social and Friedrich for involving us in such an interesting project!!
Into population dynamics? Coming to #CNS2025 but not quite ready to head home?
Come join us! at the Symposium on "Neural Population Dynamics and Latent Representations"! 🧠
📆 July 10th
📍 Scuola Superiore Sant’Anna, Pisa (and online)
👉 Free registration: neurobridge-tne.github.io
#compneuro
and with co-organizers @albmazz.bsky.social , Silvestro Micera, Calogero Oddo, @solaiman-shokur.bsky.social, Nicolo Meneghetti, Jacopo Carpaneto.
What a line up!! With Lorenzo Gaetano Amato, Demian Battaglia, @durstewitzlab.bsky.social, @engeltatiana.bsky.social, @seanfw.bsky.social, Matthieu Gilson, Maurizio Mattia, @leonardopollina.bsky.social, Sara Solla.
Into population dynamics? Coming to #CNS2025 but not quite ready to head home?
Come join us! at the Symposium on "Neural Population Dynamics and Latent Representations"! 🧠
📆 July 10th
📍 Scuola Superiore Sant’Anna, Pisa (and online)
👉 Free registration: neurobridge-tne.github.io
#compneuro
⏳ One week left to submit your abstract!
Join us in Padova for the 2025 Italian Network of Computational Neuroscience Conference 🧠🇮🇹
📅 Deadline: 14 June
Share your research and engage with the computational neuroscience community!
#INNC2025 #Neuroscience #CallForAbstracts
Excited to share my PhD paper! In it, we use targeted 2-photon optogenetic stimulation to determine how V1 activity is read-out in a detection task. We found that network influence, not visual coding properties, predicted the impact of ensembles on behavior - contradicting our expectations (1/5).
Because we must build good things while we scream about the bad, I have started a "Data for Good" team @data-for-good-team.bsky.social that partners with organizations needing short-term data science help. We have three projects ongoing & will add more as our capacity grows.
data-for-good-team.org
Please RT🙏
Reach out if you want to help understand cognition by modelling, analyzing and/or collect large scale intracortical data from 👩🐒🐁
We're a friendly, diverse group (n>25) w/ this terrace 😎 in the center of Paris! See👇 for + info about the lab
We have funding to support your application!
Dynamics days europe 2025, Thessaloniki
23-27, June 2025
MS4: Neural Dynamics Across Spatiotemporal Scales: ...
Organisers: T. Manos, A. Torcini, A. Provata, Astero
The program of our MS (25-26/6/2025) is online
#compneurosky #neuroskyence
websites.auth.gr/ddeu2025/
Re-posting is appreciated: We have a fully funded PhD position in CMC lab @cmc-lab.bsky.social (at @tudresden_de). You can use forms.gle/qiAv5NZ871kv... to send your application and find more information. Deadline is April 30. Find more about CMC lab: cmclab.org and email me if you have questions.
Out now 'in print'--- a true labor of love, in more ways than one. See the paper and press-release below!
Also, go and see @matthijspals.bsky.social's talk at #Cosyne, where he will talk about related/follow up work!
uni-tuebingen.de/en/research/...
A crowded stadium. Thrilled fans watch from the terraces, fixated by the figures on the brightly-lit court. Over the noise, the commentator shouts excitedly: "Hughes conceives a lovely hypothesis. Wilson tests it through repeated observation. Evans adds experimental data then passes back to Hughes, who states the theory in unambiguous terms and the crowd goes wild!!!"
My latest cartoon for @newscientist.com
Join us in beautiful Tokyo for a great summer school!
IRCN and Chen Institute Joint Course on Neuro-inspired Computation
ircn.jp/en/events/07...
It's finally out!
Visual experience orthogonalizes visual cortical responses
Training in a visual task changes V1 tuning curves in odd ways. This effect is explained by a simple convex transformation. It orthogonalizes the population, making it easier to decode.
10.1016/j.celrep.2025.115235
Picture of neural manifolds for the two choices in a decision-making task, depicted in 3D and in 2D
New preprint: "The geometry of the neural state space of decisions", work by Mauro Monsalve-Mercado, buff.ly/42wVHD5. Surprising results & predictions! (Thread) We analyze neuropixel population recordings in macaque area LIP during a reaction time, random-dot motion 1/
What's the right way to think about modularity in the brain? This devilish 😈 question is a big part of my research now, and it started with this paper with @solarpunkgabs.bsky.social, finally published after the first preprint in 2021! 🤖🧠🧪
www.nature.com/articles/s41...
Very cool paper by Emily Oby and colleagues:
www.nature.com/articles/s41...
Interesting insights into the flexibility (or lack thereof) of neural dynamics for motor control
📢PhD position @ Bristol Uni (Ross Purple, Sean Froudist-Walsh) and joint supervision @ Sant’Anna School of Advanced Studies (Eleonora Russo) on the reinforcement of traumatic memories during sleep using advanced machine learning techniques.
Deadline: 6 Jan. 2025
Detailed project information here 👇
📢PhD position @ Bristol Uni (Ross Purple, Sean Froudist-Walsh) and joint supervision @ Sant’Anna School of Advanced Studies (Eleonora Russo) on the reinforcement of traumatic memories during sleep using advanced machine learning techniques.
Deadline: 6 Jan. 2025
Detailed project information here 👇
🤯
Comp neuro PIs -- what was the first grant you got as a PI (collaborative, solo, big, small), and how soon after you started? My ears are open 😅
#neuroai #compneurosky #compneuro
👋🙋♀️
Hi, I would love to be added as well! thx :)
Hi, I would love to be added as well! :)
