I can’t recommend this enough.

UNBREAKING, a new project from @lizneeley.bsky.social & co, documents & explains our many concurrent institutional collapses.

It’s beautifully executed work, full of intellectual & moral clarity. 3 pages are live, more will come. It’s SO GOOD, & I learned so much.

Two new chapters from my free online book in human genetics out this weekend!
These complete Part 3 of the book, on human population structure and history:
3.3: Inferring human prehistory from genetic data [this thread]
3.4: Ancient DNA [next thread]
web.stanford.edu/group/pritch...

A cost-effective sequencing method for genetic studies combining high-depth whole exome and low-dept... npj Genomic Medicine - A cost-effective sequencing method for genetic studies combining high-depth whole exome and low-depth whole genome

Happy to share that our WEGS paper is out today in NPJ Genomic Medicine!! Many thanks to everyone who contributed to this work! Special kudos to Daniel Taliun who led this work with me!
www.nature.com/articles/s41...

I'm delighted to release the first half of my new textbook in human genetics:
web.stanford.edu/group/pritch...

"An Owner's Guide to the Human Genome: an introduction to human population genetics, variation and disease"

First author Josh Schraiber posted this new preprint of ours on the other place, but he's not on here yet, so I guess it's up to me

www.biorxiv.org/content/10.1...

And here's Josh's thread: twitter.com/jgschraiber/...

Causal interpretations of family GWAS in the presence of heterogeneous effects bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Family-based GWAS have become the gold standard for assessing causal genetic effects. They’re often said to offer an unbiased estimate of the average causal effect (ATE) of an allele or PGS. Here, we (Carl Veller & @mollyprz.bsky.social ) evaluate such statements.
www.biorxiv.org/content/10.1... 1/n