The shirt is very topical!

Fun day building a ´basic’ fiber photometry setup for green fluorescent biosensors with rotating student Lauryn! (🥹 Please excuse the lack of mounted equipment happening, this was a rough-in). As you can see by the number of LED drivers, the end result of this build will be less ‘basic’.

🚨 PI position in dept. of Neuroscience with lab located the @crchum.bsky.social

Hiring at assistant/associate prof level in the fields of neural regeneration, stem cells and spinal-associated pathologies

can-acn.org/professor-re...

Very much enjoyed my visit to Bonn & Michael Wenzel’s group for a chance to share some new data and discuss together future directions in hippocampal SD research. Excited to work together! (Also great to catch up over lunch with Martin Fuhrmann!)

Dream come true last night - Rachelle surprised me on our flight over to ICSD with tickets for Radiohead in Berlin!

Is this the perfect grant writing album?

Extremely New Mexico view from my front porch this morning:

😅

(Clearly I need to get a little more creative because when I posted my Nat Comms paper earlier this year, I also wrote “Excited to share..”!) 🥹

Congrats to my tech Briana on her first pub! 🍻

Contralesional hippocampal spreading depolarization promotes functional recovery after stroke - Nature Communications Neural mechanisms underlying deep brain strokes are not fully understood. Here authors demonstrate that spreading depolarizations occur in the intact contralesional hippocampus during unilateral strok...

Originally used here: www.nature.com/articles/s41...

Step-by-step protocol and common troubleshooting steps are all there! Stay tuned for the accompanying video!

Excited to share the first publication out of my lab!

www.jove.com/t/69418/simu...

We describe the approach that I developed during my postdoc in the Thompson Lab for inducing stroke in behaving mice while recording neuronal activity in the emerging core.

Matt, you know I’ll always be a 🇨🇦⛄️ at heart.

Still highs of 20 down here 🥹🌵

So great to have you for a visit! Looking forward to staying in touch.

FPbase Fluorescence Spectra Viewer An interactive fluorescence spectra viewer to evaluate the spectral properties of fluorescent proteins, organic dyes, filters, and detectors.

The FPbase spectra viewer just had it's biggest software refactor in 6 years. It *should* be largely invisible to the end user (hopefully just faster and less buggy). Please let me know if you find any issues as you use it!

www.fpbase.org/spectra/

Congrats to you and your team! Go Jays is right! 🇨🇦!

What makes PhD students happy? Good supervision Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research.

www.nature.com/articles/d41...

Rapid adaptive optics enabling near noninvasive high-resolution brain imaging in awake behaving mice - Nature Communications The authors present the adaptive optics system MD-FSS, which allows high-resolution brain imaging in awake mice with rapid aberrations correction against motion. It reveals differences in brain functi...

Rapid adaptive optics enabling near noninvasive high-resolution brain imaging in awake behaving mice

Under 2P excitation, adaptive optics measures the aberrated point spread function in ≈0.1 s/measurement, compensating for aberrations and scattering.

www.nature.com/articles/s41...

Fluorescently labeled astrocytes at varying distances from cortical or white matter stroke infarct border

Huge congrats @amygleichman.bsky.social on this phenomenal study, demonstrating regional differences in astrocyte responses to stroke and a key role for astrocytes in post-stroke angiogenesis and repair!

(see also - gorgeous astrocytes for fluorescence Friday)

www.sciencedirect.com/science/arti...

Experienced Albuquerque’s balloon fiesta for the first time today! Very cool.

Wow - congratulations! Cool project.

Really fun weekend exploring Southern NM - stopped in at a roastery in Hatch (home of the chile) & camped near White Sands National Park - this state is so cool!

Hippocampal SD on the cover of STM! 😍

I’m in the market for a fanless solid state (DPSS) 561 nm laser & both companies I’ve purchased from in the past seem to have either vanished or aren’t replying to my inquiries & quote requests 👻 anyone have a good source?

Cool! What a creative, yet simple, approach. Love this kind of science!

Congrats to you & Katarzyna!

Sounds very interesting! Looking forward to giving it a read today. Congrats to you and your team!

Retrograde and anterograde trans-synaptic viral tracing of neuronal connections reveals local and distant effects of ischemic stroke on dendritic spines - Myrthe Van Sprengel, Jenna Butterworth, Patri... Focal stroke leads to complex neurological disturbances with variable recovery. One explanation for this variability is that stroke disrupts local and remote ne...

Happy to share new paper from MSc grads Myrthe and Jenna. We asked the question, when part of the brain dies during stroke, what happens to local and distant cortical neurons that innervate the stroke site (in S1 cortex) or those that receive outputs? journals.sagepub.com/doi/10.1177/...