Maria's paper on characterizing trans-properties of transcription factors and how they affect gene expression is out now!

www.biorxiv.org/content/10.6...

PURE makes PURE: reconstitution of the PURE cell-free system from self-synthesized non-ribosomal proteins Building a universal biochemical constructor, an autonomously self-replicating biochemical system, is a major challenge in synthetic biology. The PURE cell-free system is an ideal starting point for e...

Saeed's latest paper is now out on bioRxiv:

"PURE makes PURE: reconstitution of the PURE cell-free system from self-synthesized non-ribosomal proteins"

www.biorxiv.org/content/10.6...

Microfluidics meets cell-free systems: from molecular engineering to synthetic cells Cell-free systems have emerged as a powerful platform for protein production, characterization, and bottom-up construction of artificial cells, offeri…

Check out Amogh's latest review:

"Microfluidics meets cell-free systems: from molecular engineering to synthetic cells"

now published in Current Opinion in Biotechnology.

www.sciencedirect.com/science/arti...

High-throughput cell-free profiling of SARS-CoV-2 RBD variants enables rapid and quantitative in vitro affinity landscape mapping www.biorxiv.org/content/10.1101/2025.09....

High-throughput cell-free profiling of SARS-CoV-2 RBD variants enables rapid and quantitative in vitro affinity landscape mapping www.biorxiv.org/content/10.1101/2025.09....

High-throughput cell-free profiling of SARS-CoV-2 RBD variants enables rapid and quantitative in vitro affinity landscape mapping SARS-CoV-2 variants continue to threaten public health, necessitating the study of cumulative and epistatic effects of receptor-binding domain (RBD) mutations on antibody evasion. We present a high-th...

Laura and Jiami's paper is out now on BioRxiv! Nice collaboration with the Reddy lab at ETHZ:

"High-throughput cell-free profiling of SARS-CoV-2 RBD variants enables rapid and quantitative in vitro affinity landscape mapping."

www.biorxiv.org/content/10.1...

Hello World !!
The Maerkl Lab is now on Bluesky...

#syntheticbiology #cellfree #microfluidics #transcriptinalregulation