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Posts by Mitchell Ostrow

Rajan Lab at Cosyne
Thurs., March 12 20:30-23:30 Pavilion 1 Poster Session 1
#1-059: Active electrosensing and communication in MARL-trained weakly electric fish foraging agents
Sonja Johnson-Yu*, Satpreet Singh*, Zhouyang Lu, Aaron Walsman, Federico Pedraja, Denis Turcu, Pratyusha Sharma, Naomi Saphra, Nathaniel Sawtell, Kanaka Rajan
*co-first authors
Sat., March 14 11:45-12:00 Auditorium I Session 7: Dynamical Inference
InputDSA: Demixing then comparing recurrent and externally driven dynamics
Ann Huang*, Mitchell Ostrow*, Satpreet Singh, Leo Kozachkov, Ila Fiete, Kanaka Rajan
*co-first authors

Rajan Lab at Cosyne Thurs., March 12 20:30-23:30 Pavilion 1 Poster Session 1 #1-059: Active electrosensing and communication in MARL-trained weakly electric fish foraging agents Sonja Johnson-Yu*, Satpreet Singh*, Zhouyang Lu, Aaron Walsman, Federico Pedraja, Denis Turcu, Pratyusha Sharma, Naomi Saphra, Nathaniel Sawtell, Kanaka Rajan *co-first authors Sat., March 14 11:45-12:00 Auditorium I Session 7: Dynamical Inference InputDSA: Demixing then comparing recurrent and externally driven dynamics Ann Huang*, Mitchell Ostrow*, Satpreet Singh, Leo Kozachkov, Ila Fiete, Kanaka Rajan *co-first authors

📍 #Cosyne26 bound?

Thrilled to have PhD students @annhuang42.bsky.social and Sonja Johnson-Yu representing the Rajan Lab this year. Shout out to co-first authors @satpreetsingh.bsky.social and @neurostrow.bsky.social.

Catch their sessions to learn about our newest work 🧠🤖

#NeuroAI #CompSci

1 month ago 25 5 0 0

Accepted to ICLR! see you in 🇧🇷

2 months ago 13 1 0 0

The original dynamic similarity analysis (DSA) developed by @neurostrow.bsky.social and Ila Fiete is a powerful method to compare trajectories of (nonlinear) neural dynamics between different datasets and models: arxiv.org/abs/2306.10168

3 months ago 6 2 1 0
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Wanna compare dynamics across neural data, RNNs, or dynamical systems? We got a fast and furious method🏎️
The 1st preprint of my PhD 🥳 fast dynamical similarity analysis (fastDSA):
📜: arxiv.org/abs/2511.22828
💻: github.com/CMC-lab/fast...
I’ll be @cosynemeeting.bsky.social - happy to chat 😉

3 months ago 114 35 1 4

Causal to what? we know from biophysics how spikes causally trigger neurotransmitter release, and how neurotransmitters cause PSPs, which trigger spiking in post synaptic neurons etc…

4 months ago 4 0 0 0

Woah huge!! Congrats

4 months ago 1 0 0 0

At #NeurIPS2025!

🎉 Excited to present Conditionally Linear Dynamical Systems (CLDS). We leverage the dependence of neural dynamics on task covariates to yield an interpretable, flexible model of dynamics.

Come meet and check it out!
📍: Poster #2209, Hall C,D,E on Thu Dec 4, 11 am–2 pm, PST.

🧵/6

4 months ago 19 5 1 1
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Chain-of-Thought Hijacking Large reasoning models (LRMs) achieve higher task performance with more inference-time computation, and prior works suggest this scaled reasoning may also strengthen safety by improving refusal. Yet w...

similarly: arxiv.org/abs/2510.26418

4 months ago 2 0 0 0
Characterizing control between interacting subsystems with deep... Biological function arises through the dynamical interactions of multiple subsystems, including those between brain areas, within gene regulatory networks, and more. A common approach to...

13/ 😀Feel free to reach out to discuss this work, or the application of it to your field of study. Or come swing by our poster at #NeurIPS2025. We’d love to chat!

📄 Paper: openreview.net/forum?id=I82...
💾 Code: github.com/adamjeisen/J...
📍 Poster: Thu 4 Dec 11am - 2pm PST (#2111)

4 months ago 11 3 2 0

Really proud of this project with @adamjeisen.bsky.social
- Jacobian estimation is a challenging and generic problem in dynamics, and I’m excited for all the future use cases of our method! See you at NeurIPS 🧠💻

4 months ago 8 1 0 0
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How do brain areas control each other? 🧠🎛️

✨In our NeurIPS 2025 Spotlight paper, we introduce a data-driven framework to answer this question using deep learning, nonlinear control, and differential geometry.🧵⬇️

4 months ago 89 30 1 3

Also, from a dynamics perspective, directions with very little variance (in a statistical perspective) can still have an outsized effect on the activity on directions with larger variance!

4 months ago 3 1 0 0

Controversial take: our ICLR reviews actually helped make our paper better

5 months ago 7 1 2 0

Thanks again to all my amazing collaborators, especially my co-first author @annhuang42.bsky.social !

5 months ago 3 0 0 0
GitHub - mitchellostrow/DSA at inputdsa Dynamical Similarity Analysis code accompanying the paper "Beyond Geometry: comparing the temporal structure of computation in neural circuits via dynamical similarity analysis" - GitHub ...

Public code is here github.com/mitchellostr... , and it is soon to be merged into the DSA package (pip install dsa-metric)

5 months ago 3 0 1 0

Second, we develop a new similarity metric based in control theory and shape metrics, which is extremely fast and robust (no figure here)! The metric is based on controllability, which measures how easily inputs can arbitrarily move the state of a dynamical system.

5 months ago 3 0 1 0
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First, we apply subspace id methods from classical control theory to learn input-controlled linear dynamical systems (key in partially observed settings). This is new for the Dynamic Mode Decomposition (DMD) literature, and the method robust to extreme partial observation (12/)

5 months ago 4 0 1 0

Now for the 🤓 : InputDSA leverages 2 new technical developments (11/)

5 months ago 2 0 1 0

We think that inputDSA could be especially useful when experimentalists can perturb a system (e.g with optogenetics) for system identification. (10/)

5 months ago 3 0 1 0

As with DSA, inputDSA complements other comparison metrics (@itsneuronal.bsky.social , @mschrimpf.bsky.social ). One important result we found is that even for input-driven dynamics, the original DSA still gives good comparisons, but inputDSA can sharpen them! (9/)

5 months ago 3 0 1 0
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On two datasets, we apply random perturbations (noise, functions) to the true input, or utilize other task variables when performing inputDSA. We measure the correlation between the surrogate and true scores, finding that in general, inputDSA is quite robust! (8) (shoutout @oliviercodol.bsky.social)

5 months ago 5 0 1 0

One more analysis with greater implications: In most neuroscience settings, we don’t know the true inputs to a brain region. When we build models, we apply proxy inputs that we think are related to the true input. With InputDSA, we can evaluate this! (7/) (as in e.g line attractors in hypothalamus))

5 months ago 4 0 1 0
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Second: on @thomas-zhihao-luo.bsky.social recently showed that rat cortical dynamics transition from primarily input-driven to autonomous during a 2-alternative forced choice task. InputDSA corroborates this, showing that cortex becomes less input-controllable across time! (6/)

5 months ago 5 0 1 0
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On @satpreetsingh.bsky.social ’s Deep RL fly navigation task (from @bingbrunton.bsky.social ’s lab) we show that successful models become more similar to each other across training, while unsuccessful ones diverge in inputDSA score —an Anna Karenina/universality result! (5/)

5 months ago 3 0 1 0

Let’s look at some cool applications first! We made a lot of technical developments, but I'll save those till the end 🤓 :

5 months ago 2 0 1 0
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The basic idea of DSA: approximate your dynamics so that comparison is tractable. This is backed by Koopman Operator Theory and relates to work done by @wtredman.bsky.social and Igor Mezic. InputDSA naturally extends DSA—we can compare intrinsic dynamics, the effect of input, or both jointly! (3/)

5 months ago 4 0 1 0

We introduce InputDSA, a method that builds on our prior work, Dynamical Similarity Analysis (DSA) to quantitatively compare input-drive dynamical systems! Especially relevant for neuroscience, but it can be applied to any type of time series data ! 🧠 💻 🌴 💨 💵 🔥 (2/)

5 months ago 4 0 1 0
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Our next paper on comparing dynamical systems (with special interest to artificial and biological neural networks) is out!! Joint work with @annhuang42.bsky.social , as well as @satpreetsingh.bsky.social , @leokoz8.bsky.social , Ila Fiete, and @kanakarajanphd.bsky.social : arxiv.org/pdf/2510.25943

5 months ago 70 24 4 5
OSF

Very excited to share a new preprint that’s been brewing for a long time! This work was led by the exceptional @traceym.bsky.social, and made possible by a developmental + comparative + computational dream team.

osf.io/preprints/ps...

6 months ago 14 5 1 1

This doesn't say anything about how the attractors is instantiated, ie the equation itself (let alone its mapping to the biology, which is another criterion needed for a mechanism according to Craver). I'm fine with this claim if it's what the post means!

9 months ago 3 0 1 0