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Posts by Paul Hill

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New paper in Imaging Neuroscience by Jonas Kransberg, Kristine B. Walhovd, et al:

Failure to detect entorhinal grid-like signals in a passive navigation human fMRI study

doi.org/10.1162/IMAG...

1 week ago 5 2 0 0
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Replicability of representational similarity and its role in successful memory retrieval Abstract. Studies of hippocampal pattern similarity during event encoding and its relationship to subsequent memory retrieval have revealed inconsistent results. Our lab recently found evidence that d...

Replicability of representational similarity and its role in
successful memory retrieval

direct.mit.edu/imag/article...

2 weeks ago 13 7 0 0
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Challenges in Navigation Research This open access book explores navigation across species using a multidisciplinary approach to address challenges in research and clinical applications.

This book has just been published, open access, edited by Ken Cheng and me. It contains multiple chapters originating in a wonderful Strungmann Forum held in Frankfurt around a year ago.
link.springer.com/book/10.1007...

2 weeks ago 21 10 0 0
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Aging reorganizes human large-scale brain networks, with consequences for cognition & dementia risk. We’ve now mapped brain network changes over a wide range of the mouse lifespan. The changes mirror key features of human aging, but not entirely

New @pnas.org paper🧵

www.pnas.org/doi/10.1073/...

3 weeks ago 24 7 1 4
Headshot of Dr. Denise C. Park

Headshot of Dr. Denise C. Park

Honoring Dr. Denise C. Park, the Aging, Neuropsychology, & Cognition journal invites manuscripts building on her work. Send your 200-word abstract and cover letter to Dr. Ian McDonough: imcdonough@binghamton.edu by Aug 31. Decisions on invitations for full submissions will be made by Sep 30.

3 weeks ago 1 3 0 0

Some relevant papers:

Real-world transfer
dx.doi.org/10.1163/2213...
doi.org/10.1080/1387... (you’ll know this one)

Gait
doi.org/10.1186/s129...
doi.org/10.3389/fbio...

4 weeks ago 0 0 0 0

Thanks, Hugo, this was a fun review to put together. Whether ambulatory VR maps onto real-world behavior is still an open question. Spatial learning often transfers better than stationary VR, but not as well as real-world learning itself. Some motor measures also differ from real-world behavior.

4 weeks ago 2 0 2 0
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Toward embodied, ecological cognition with ambulatory virtual reality Virtual reality (VR) is a powerful tool for bridging ecological validity and experimental control in cognitive science. VR techniques enable more naturalistic behavior and offer value for assessment and rehabilitation in aging and clinical populations. In this review, we describe how emerging ambulatory VR approaches that support more naturalistic movements, actions, and interactions within immersive environments offer important advances for studying cognition and neural systems in ecologically valid contexts. We highlight the ways in which ambulatory VR paradigms enrich memory, navigation, and cognitive control through embodied sensorimotor engagement, and explore the mechanistic basis for these enhancements, including potential compensatory components in aging and disease. We also discuss methodological challenges and opportunities for combining ambulatory VR with mobile neuroimaging.

Online Now: Toward embodied, ecological cognition with ambulatory virtual reality

1 month ago 12 5 1 1
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Excited to announce our new paper in Trends in Cognitive Science (TICS) on the importance of naturalistic body movements and mobile immersive virtual reality to the study of cognition! Check it out!

www.sciencedirect.com/science/arti...

1 month ago 26 8 0 0
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In Memory of Dr. Denise C. Park In Memory of Dr. Denise C. Park Dr. Denise C. Park passed away on Sunday, February 1, 2026, at age 74. She was a beloved cognitive neuroscientist and colleague whose remarkable career spanned over 50…

We are deeply saddened to share that Dr. Denise C. Park, founder of CVL, passed away on Sunday, Feb 1. A pioneering cognitive neuroscientist, mentor, & leader, Dr. Park shaped the study of memory, aging, & the brain. Read the full remembrance here: cvl.utdallas.edu/in-memory-of-dr-denise-c-park/

2 months ago 12 9 0 1
Vulnerability to memory decline in aging revealed by a mega-analysis of structural brain change - Nature Communications Across 13 longitudinal studies (3,737 adults), the authors show that brain atrophy parallels memory loss, with a stronger coupling in later life. APOE ε4 increases decline, yet genetic risk does not m...

Impressive MEGA-analysis:

Vulnerability to memory decline in aging revealed by a mega-analysis of structural brain change
www.nature.com/articles/s41...

4 months ago 14 4 0 1
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Headed to SfN? My group will be presenting new work on aging, memory, and immersive VR, including early Alzheimer’s markers, aphantasia, and a new VR tool for spatial behavior. Come check us out.

5 months ago 3 2 0 0
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fMRI BOLD signals in the left angular gyrus and hippocampus are associated with memory precision Abstract. It has been proposed that the neural correlates of successful memory retrieval can be dissociated from the correlates of retrieval precision (fidelity). The specific findings supporting this...

Update: our latest paper is now available with open access: doi.org/10.1162/IMAG...
Hou and colleagues reveal the unique role of both the hippocampus and angular gyrus in supporting high fidelity episodic memories!

5 months ago 9 4 0 0
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EPFL-Smart-Kitchen-30: Densely annotated cooking dataset with 3D kinematics to challenge video and language models Understanding behavior requires datasets that capture humans while carrying out complex tasks. The kitchen is an excellent environment for assessing human motor and cognitive function, as many complex...

Understanding behavior requires datasets that capture humans while carrying out complex tasks. The kitchen is an excellent environment for assessing human motor and cognitive function, as many complex actions are naturally exhibited in kitchens from chopping to 🧽!

arxiv.org/abs/2506.01608

6 months ago 73 15 5 4
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New paper alert! 🚨 We show that age-related neural dedifferentiation in scene-selective cortex is tied to changes in eye movements. Using simultaneous fMRI + eye-tracking, we found that younger adults’ fixations covary with scene specificity, but this link weakens with age.

Link in post below 👇

7 months ago 35 6 1 0
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🚨 New preprint! 🚨

Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇

📄 www.biorxiv.org/content/10.1...
💻 code + data 🔗 below 🤩

#neuroskyence

7 months ago 135 58 10 6
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Evidence gap in blood biomarkers for Alzheimer’s disease Willem van Gool and colleagues argue that moves to use blood biomarkers in clinical practice or population screening are inappropriate without evidence on outcomes important to patients and carers T...

Out of 800+ studies on blood-based biomarkers for Alzheimer's, not a single one measured actual changes in patient outcomes.

doi.org/10.1136/bmj-...

7 months ago 2 1 0 0
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The vascular contribution to cognitive decline in ageing and dementia - Nature Reviews Neuroscience Growing evidence suggests that reduced cerebral blood flow contributes to cognitive decline in ageing and dementia. Attwell and colleagues discuss the underlying mechanisms and functional consequences...

Delighted to share our latest review in Nature Reviews Neuroscience!
We examine the growing evidence that vascular dysfunction plays a key role in cognitive decline in ageing and dementia, and argue that preserving/restoring CBF should be central to future therapies.
www.nature.com/articles/s41...

8 months ago 72 27 3 1
Function over form: The temporal evolution of affordance-based scene categorization | JOV | ARVO Journals

🚨 New paper in Journal of Vision!
We show that scene affordances—what you can do in a space—shape how we perceive and categorize scenes. This shapes your similarity preferences, predicts your categorization false alarms, and even alters neural representations. 🧵👇
🔗 doi.org/10.1167/jov....
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9 months ago 26 9 3 0

JNeurosci’s Early career researcher (ECR) Advisory Board just opened a call for applications (due July 18 at 5pm ET). Join our team for a unique opportunity to serve the ECR community and advocate for ECR needs in scientific publishing: www.jneurosci.org/content/ecr-...
@sfnjournals.bsky.social

9 months ago 1 1 0 0
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New Paper Alert! de Chastelaine et al found that young adults are able to employ 'retrieval gating' to allow mnemonic content to be aligned with a retrieval goal, but older adults failed to do this even when their memory was boosted to match young adults! www.sciencedirect.com/science/arti...

9 months ago 5 2 0 1

Representation of locomotive action affordances in human behavior, brains, and deep neural networks

www.pnas.org/doi/epub/10....

10 months ago 11 3 0 0

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Cortex Special Issue honoring Dr. Francesca Frassinetti: From Bodies to Spaces: a neurocognitive/neuropsychological perspective on body-space interactions

11 months ago 0 0 0 0

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By integrating physical mobility and sensorimotor function into models of spatial navigation, we hope to broaden the scope of how navigation is studied, assessed, and ultimately used to detect preclinical changes in Alzheimer’s disease.

11 months ago 1 0 1 0

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We propose that spatial navigation offers a useful lens into early cognitive-motor changes in aging, shaped by neuromodulatory and multisensory processes that may decline before overt brain pathology.

11 months ago 0 0 1 0
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Rather than focusing solely on hippocampal or entorhinal dysfunction, we highlight how degraded sensorimotor inputs - like balance, gait, and vestibular function - play a crucial but often overlooked role.

11 months ago 0 0 1 0

In a recent review, @adekstreme.bsky.social and I revisit how spatial navigation breaks down in aging and early Alzheimer’s disease - and why it’s not just about the brain.

doi.org/10.1016/j.co...

#SpatialNavigation #AgingBrain #EmbodiedCognition #AlzheimerResearch

11 months ago 4 2 1 1
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Senior Research Associate (RA2312) in University of East Anglia | UEA View details and apply for this Senior Research Associate (RA2312) vacancy in University of East Anglia. School of Psychology Faculty of Social Sciences Senior Research Associate Ref: RA...

Please share; My lab at @psychologyuea.bsky.social @uniofeastanglia.bsky.social is recruiting a post-doc for a cognitive neuroscience memory project. It is a 3-year post, with a proposed start date of 8th September. Application deadline is 15th of June.

vacancies.uea.ac.uk/vacancies/15...

11 months ago 17 28 1 2

It is important now more than ever for scientists to share their work with the general public. I am pleased to have contributed to investNScience’s campaign which they are currently running across numerous social media platforms. It is a great initiative that makes science more relevant to everyone.

1 year ago 8 2 2 0
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Are you attending #CNS2025 ? If so, then you should stop by my poster on Tuesday morning for a fun chat about fmri and spatial memory!!

1 year ago 15 5 0 0