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Posts by Isabella Childers

Comparative Genomics Reveals the Ancestral Recombination Landscape of Placental Mammals www.biorxiv.org/content/10.64898/2026.04...

2 weeks ago 5 1 0 0
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An ancient recombination desert is a speciation supergene in placental mammals - Nature Deep learning methods identified a large and evolutionarily conserved X-linked low recombination region in placental mammals that serves as both a barrier to gene flow in hybridizing lineages and an a...

Please check out the newly published Murphy lab’s new paper in @nature.com! www.nature.com/articles/s41...

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Recombination-aware phylogenomics Phylogenetic variation, recombination rate evolution, and comparative genome structure and organization have typically been explored in isolation. The chromosomal and genomic context of selected genetic markers in phylogenetic studies is usually unknown, given the fragmented nature of most genome assemblies. It is now established that the position of markers in the genome can strongly influence the inferred phylogeny, often not reflecting speciation patterns and subsequent bifurcating tree structure but rather post-speciation introgression. The recent availability of chromosome-level genome assemblies and advances in estimating genome-wide recombination rates have created opportunities to jointly understand the interplay of chromosome evolution, the landscape of recombination, and phylogenetic signal.

Online now: Recombination-aware phylogenomics

9 months ago 8 5 0 0